Search Results - "R, S.K."

Enhancing preclinical drug discovery with artificial intelligence by Vijayan, R.S.K., Kihlberg, Jan, Cross, Jason B., Poongavanam, Vasanthanathan

“…•The use of AI-driven solutions to enable pre-clinical drug discovery is growing steadily within the pharmaceutical industry.•AI technologies can be leveraged…”
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A Study to Evaluate Influence of Bladder Contrast Agent in Monte Carlo Dose Calculation Algorithm for Advanced Radiotherapy Techniques by Bhalla, N.K., Palanisamy, M., A, S., R, S.K., Abraham, M., Puri, A.

“…Purpose of this study is to evaluate the Monte Carlo (MC) dose calculation accuracy between contrast and non-contrast-base Computed tomography (CT) images used…”
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Abundance/occupancy/patchiness relations in estuarine seagrass macrobenthos by Barnes, R.S.K.

“…Using >1800 macrobenthic samples from 25 representative intertidal seagrass sites in the Knysna estuarine bay (warm-temperate South Africa),…”
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Structure-based classification predicts drug response in EGFR-mutant NSCLC by Robichaux, Jacqulyne P., Le, Xiuning, Vijayan, R. S. K., Hicks, J. Kevin, Heeke, Simon, Elamin, Yasir Y., Lin, Heather Y., Udagawa, Hibiki, Skoulidis, Ferdinandos, Tran, Hai, Varghese, Susan, He, Junqin, Zhang, Fahao, Nilsson, Monique B., Hu, Lemei, Poteete, Alissa, Rinsurongkawong, Waree, Zhang, Xiaoshan, Ren, Chenghui, Liu, Xiaoke, Hong, Lingzhi, Zhang, Jianjun, Diao, Lixia, Madison, Russell, Schrock, Alexa B., Saam, Jennifer, Raymond, Victoria, Fang, Bingliang, Wang, Jing, Ha, Min Jin, Cross, Jason B., Gray, Jhanelle E., Heymach, John V.

“…Epidermal growth factor receptor ( EGFR ) mutations typically occur in exons 18–21 and are established driver mutations in non-small cell lung cancer (NSCLC) 1…”
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The occurrence of a rich subtidal macrobenthic fauna in through-flow residential marina canals, and the potential of such systems to be managed as biodiversity assets by Barnes, R.S.K., Seath, J.L.

“…The subtidal soft-sediment macrobenthos of a residential coastal marina's 25 ha through-flow canal system was investigated in relation to that in the adjacent…”
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Seagrass macrobenthic biodiversity does not vary in conformity with a leaky-lagoonal confinement gradient by Barnes, R.S.K.

“…Coastal lagoon ecology often changes on progression from the open, well-flushed mouth region to the depositional zone furthest from the open sea. This is…”
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Morisita's index of patchiness and edge effects: A response to Butturi-Gomes and Petrere (2020) by Barnes, R.S.K.

“…•Conclusions of Barnes and Laurie (2018) not falsified by edge effects.•Patchiness observed by Barnes and Laurie (2018) not edge avoidance.•Patchiness observed…”
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Intraspecific Abundance–Occupancy–Patchiness Relations in the Intertidal Benthic Macrofauna of a Cool-Temperate North Sea Mudflat by Barnes, R. S. K.

“…The macroecological variable of patchiness (Lloyd’s I p index of patchiness, P ) has recently been shown to be related inter- and intraspecifically to those of…”
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Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity by Robichaux, Jacqulyne P., Elamin, Yasir Y., Vijayan, R.S.K., Nilsson, Monique B., Hu, Lemei, He, Junqin, Zhang, Fahao, Pisegna, Marlese, Poteete, Alissa, Sun, Huiying, Li, Shuai, Chen, Ting, Han, Han, Negrao, Marcelo Vailati, Ahnert, Jordi Rodon, Diao, Lixia, Wang, Jing, Le, Xiuning, Meric-Bernstam, Funda, Routbort, Mark, Roeck, Brent, Yang, Zane, Raymond, Victoria M., Lanman, Richard B., Frampton, Garrett M., Miller, Vincent A., Schrock, Alexa B., Albacker, Lee A., Wong, Kwok-kin, Cross, Jason B., Heymach, John V.

“…We characterized the landscape and drug sensitivity of ERBB2 (HER2) mutations in cancers. In 11 datasets (n = 211,726), ERBB2 mutational hotspots varied across…”
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Interspecific abundance-occupancy relations along estuarine gradients by Barnes, R.S.K.

“…Do interspecific abundance-occupancy (A-O) relationships vary systematically along environmental gradients? A-O relationships of macrobenthic assemblages of…”
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Do beds of subtidal estuarine seagrass constitute a refuge for macrobenthic biodiversity threatened intertidally? by Barnes, R. S. K., Claassens, L.

“…Biodiversity differentials between macrobenthic assemblages associated with adjacent intertidal and subtidal areas of a single seagrass system were…”
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Interspecific relationship of patchiness to occupancy and abundance, as exemplified by seagrass macrobenthos by Barnes, R.S.K.

“…[Display omitted] •Relations of Lloyd's Ip macrobenthic patchiness studied in 6 types of seagrass.•Interspecific patchiness closely correlated with…”
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Spatial structure of a multi-species guild: the dominant biofilm-grazing microgastropods of seagrass by Barnes, R. S. K.

“…Although all-too-often ignored ecologically, gastropods < 5 mm in largest dimension may be dominant aquatic assemblage components. In Moreton Bay, Australia,…”
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Differential sampling in the assessment of conservation and biodiversity merit: a comparison of the seagrass macrofauna in three nearby South African estuaries by Barnes, R. S. K., Seath, J. L., Arendse, C. J.

“…To what extent is the relative biodiversity of some flagship conservation sites a result of differential attention? Knysna estuarine bay is the topmost ranked…”
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What does measuring species diversity in estuarine seagrass systems actually assess? by Barnes, R.S.K.

“…Relationships between species diversity and other species-density and species-richness metrics were investigated in the seagrass macrobenthos of Knysna…”
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Patterns of seagrass macrobenthic biodiversity in the warm-temperate Knysna estuarine bay, Western Cape: a review by Barnes, R. S. K.

“…Knysna estuarine bay in South Africa's Garden Route National Park is that country's most significant estuarine system for biodiversity and conservation value…”
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Do species display characteristic intraspecific levels of patchiness in a given habitat type? The case of intertidal seagrass macrobenthos by Barnes, R. S. K.

“…Intertidal macrobenthic assemblages associated with monospecific stands of Zostera muelleri , Cymodocea serratula , Halodule uninervis and Halophila ovalis…”
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Conformational Analysis of the DFG-Out Kinase Motif and Biochemical Profiling of Structurally Validated Type II Inhibitors by Vijayan, R. S. K., He, Peng, Modi, Vivek, Duong-Ly, Krisna C., Ma, Haiching, Peterson, Jeffrey R., Dunbrack, Roland L., Levy, Ronald M.

“…Structural coverage of the human kinome has been steadily increasing over time. The structures provide valuable insights into the molecular basis of kinase…”
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Within-species relationship of patchiness to both abundance and occupancy, as exemplified by seagrass macrobenthos by Barnes, R. S. K.

“…For the first time, intraspecific relationships between the macroecological metrics patchiness (P) and both abundance (A) and occupancy (O) were investigated…”
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Economic and environmental indicators of sustainable rice cultivation: A comparison across intensive irrigated rice cropping systems in six Asian countries by Devkota, Krishna Prasad, Pasuquin, Estela, Elmido-Mabilangan, Abigail, Dikitanan, Rowell, Singleton, Grant R., Stuart, Alexander M., Vithoonjit, Duangporn, Vidiyangkura, Ladda, Pustika, Arlyna Budi, Afriani, Riefna, Listyowati, Charisma Lia, Keerthisena, R.S.K., Kieu, Nguyen Thi, Malabayabas, Arelene Julia, Hu, Ruifa, Pan, Junfeng, Beebout, Sarah E.J.

“…[Display omitted] •Yield gap of 24–42%, profit gap of 36–82% and gaps in other indicators exists in six Asian countries.•In Vietnam, >80% of pesticide…”
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