Search Results - "Qvortrup, Katrine"

A General Strategy for Organocatalytic Activation of C–H Bonds via Photoredox Catalysis: Direct Arylation of Benzylic Ethers by Qvortrup, Katrine, Rankic, Danica A, MacMillan, David W. C

“…Direct C–H functionalization and arylation of benzyl ethers has been accomplished via photoredox organocatalysis. The productive merger of a thiol catalyst and…”
Get full text

Convergent Total Synthesis of Exochelin 772SM by Jansen, Charlotte Uldahl, Nørskov, Amalie, Mortensen, Kim T., Qvortrup, Katrine M.

“…A convergent total synthesis of the natural mycobacterial iron chelator desferri-exochelin 772SM (D-EXO) is described. The synthetic procedure proceeds in 11…”
Get full text

In-Bead Screening of Hydroxamic Acids for the Identification of HDAC Inhibitors by Qvortrup, Katrine, Nielsen, Thomas E.

“…A one bead–one compound screening format is presented. Following solid‐phase synthesis on a photolabile linker, library compounds were readily released and…”
Get full text

Chemoenzymatic indican for light-driven denim dyeing by Bidart, Gonzalo Nahuel, Teze, David, Jansen, Charlotte Uldahl, Pasutto, Eleonora, Putkaradze, Natalia, Sesay, Anna-Mamusu, Fredslund, Folmer, Lo Leggio, Leila, Ögmundarson, Olafur, Sukumara, Sumesh, Qvortrup, Katrine, Welner, Ditte Hededam

“…Blue denim, a billion-dollar industry, is currently dyed with indigo in an unsustainable process requiring harsh reducing and alkaline chemicals. Forming…”
Get full text

Targeted delivery of alcohol-containing payloads with antibody-drug conjugates by Grier, Katja E, Hansen, Anders H, Haxvig, Christina S, Li, Xin, Krigslund, Oliver, Behrendt, Niels, Engelholm, Lars H, Rossi, Fabio, Sousa, Bebiana C, Harradence, Grant J, Camper, Nicolas, Qvortrup, Katrine M

“…We herein describe the cell-specific release of alcohol-containing payloads a sulfatase-sensitive linker in antibody-drug conjugates (ADCs). The linker shows…”
Get more information

Identification of small molecules that interfere with c-di-GMP signaling and induce dispersal of Pseudomonas aeruginosa biofilms by Andersen, Jens Bo, Hultqvist, Louise Dahl, Jansen, Charlotte Uldahl, Jakobsen, Tim Holm, Nilsson, Martin, Rybtke, Morten, Uhd, Jesper, Fritz, Blaine Gabriel, Seifert, Roland, Berthelsen, Jens, Nielsen, Thomas Eiland, Qvortrup, Katrine, Givskov, Michael, Tolker-Nielsen, Tim

“…Microbial biofilms are involved in a number of infections that cannot be cured, as microbes in biofilms resist host immune defenses and antibiotic therapies…”
Get full text

Small Molecule Anti-biofilm Agents Developed on the Basis of Mechanistic Understanding of Biofilm Formation by Qvortrup, Katrine, Hultqvist, Louise Dahl, Nilsson, Martin, Jakobsen, Tim Holm, Jansen, Charlotte Uldahl, Uhd, Jesper, Andersen, Jens Bo, Nielsen, Thomas E, Givskov, Michael, Tolker-Nielsen, Tim

“…Microbial biofilms are the cause of persistent infections associated with various medical implants and distinct body sites such as the urinary tract, lungs,…”
Get full text

Surface-confined redox-active monolayers of a multifunctional anthraquinone derivative on nanoporous and single-crystal gold electrodes by Yan, Xiaomei, Jansen, Charlotte Uldahl, Diao, Fangyuan, Qvortrup, Katrine, Tanner, David, Ulstrup, Jens, Xiao, Xinxin

“…[Display omitted] •A new anthraquinone derivative is adsorbed on the gold electrodes via Au-S bonding.•The anthraquinone derivative accommodates several…”
Get full text

Upscaling and Risk Evaluation of the Synthesis of the 3,5-Diamino-1H-Pyrazole, Disperazol by Jansen, Charlotte Uldahl, Grier, Katja Egeskov, Andersen, Jens Bo, Hultqvist, Louise Dahl, Nilsson, Martin, Moser, Claus, Graz, Michael, Tolker-Nielsen, Tim, Givskov, Michael, Qvortrup, Katrine

“…This paper presents the work performed to transition a lab-scale synthesis (1 g) to a large-scale (400 g) synthesis of the 3-5-diamino-1H-Pyrazole Disperazol,…”
Get full text

Itaconimides as Novel Quorum Sensing Inhibitors of Pseudomonas aeruginosa by Fong, July, Mortensen, Kim T, Nørskov, Amalie, Qvortrup, Katrine, Yang, Liang, Tan, Choon Hong, Nielsen, Thomas E, Givskov, Michael

“…is known as an opportunistic pathogen that often causes persistent infections associated with high level of antibiotic-resistance and biofilms formation…”
Get full text

Cyanide and chloroform detection through J-aggregates based aggregation induced emission probe with real sample applications by Pervaiz, Aqsa, Shahzad, Sohail Anjum, Assiri, Mohammed A., Javid, Tayyeba, Irshad, Hasher, Qvortrup, Katrine

“…Isopthalamide based probe DPI has been synthesized by an easy two-step substitution reaction. Unique fluorescence properties of probe DPI were exploited for…”
Get full text

SAR study of 4-arylazo-3,5-diamino-1H-pyrazoles: identification of small molecules that induce dispersal of Pseudomonas aeruginosa biofilms by Jansen, Charlotte U, Uhd, Jesper, Andersen, Jens B, Hultqvist, Louise D, Jakobsen, Tim H, Nilsson, Martin, Nielsen, Thomas E, Givskov, Michael, Tolker-Nielsen, Tim, Qvortrup, Katrine M

“…By screening of a collection of 50 000 small-molecule compounds, we recently identified 4-arylazo-3,5-diamino-1 H -pyrazoles as a novel group of anti-biofilm…”
Get full text

Synthesis and biological evaluation of dihydropyrano-[2,3-c]pyrazoles as a new class of PPARγ partial agonists by Qvortrup, Katrine, Jensen, Jakob F, Sørensen, Mikael S, Kouskoumvekaki, Irene, Petersen, Rasmus K, Taboureau, Olivier, Kristiansen, Karsten, Nielsen, Thomas E

“…Peroxisome proliferator-activated receptor γ (PPARγ) is a well-known target for thiazolidinedione antidiabetic drugs. In this paper, we present the synthesis…”
Get full text

Solvent-Controlled Chemoselectivity in the Photolytic Release of Hydroxamic Acids and Carboxamides from Solid Support by Qvortrup, Katrine, Petersen, Rico G, Dohn, Asmus O, Møller, Klaus B, Nielsen, Thomas E

“…The synthetic utility and theoretical basis of a photolabile hydroxylamine-linker are presented. The developed protocols enable the efficient synthesis and…”
Get full text

Novel AIE and solvatochromism exhibiting TPE based organic fluorophore with excellent emission properties in solid and solution phase for latent fingerprint and metronidazole sensing in real samples by Irshad, Hasher, Khadija, Qvortrup, Katrine

“…•A novel TPE based organic probe TC was synthesized in single step.•The probe TC showed solvatochromism and excellent AIE behavior.•Probe TC successfully…”
Get full text

The effect of number of layers of nanoporous gold films on their electrochemical behaviour by Shan, Zhengyang, Jansen, Charlotte Uldahl, Yesibolati, Murat Nulati, Yan, Xiaomei, Qvortrup, Katrine, Ulstrup, Jens, Xiao, Xinxin

“…Nanostructured material based electrodes are frequently used in electrochemical analysis and catalysis for their multifarious favourable properties. The deep…”
Get full text

A tetrathiafulvalene–perylene diimide conjugate prepared via click chemistry by Qvortrup, Katrine, Petersen, Michael Åxman, Hassenkam, Tue, Nielsen, Mogens Brøndsted

“…‘Click chemistry’ provides a method for preparing tetrathiafulvalene (TTF)–perylene diimide (PDI) conjugates. A new tetrathiafulvalene (TTF)–perylene diimide…”
Get full text

Bead-based screening in chemical biology and drug discovery by Komnatnyy, Vitaly V, Nielsen, Thomas E, Qvortrup, Katrine

“…High-throughput screening is an important component of the drug discovery process. The screening of libraries containing hundreds of thousands of compounds…”
Get more information

Structural design of anthraquinone bridges in direct electron transfer of fructose dehydrogenase by Jansen, Charlotte Uldahl, Yan, Xiaomei, Ulstrup, Jens, Xiao, Xinxin, Qvortrup, Katrine

“…Multi-functional small molecules attached to an electrode surface can bind non-covalently to the redox enzyme fructose dehydrogenase (FDH) to ensure efficient…”
Get full text

A twistable aggregation induced emission enhancement active multisite fluorescent sensor for targeted sensing of zinc ions, 4-nitrophenol and chloroform in diverse conditions by Javid, Tayyeba, Assiri, Mohammed A., Pervaiz, Aqsa, Irshad, Hasher, Qvortrup, Katrine, Shahzad, Sohail Anjum

“…[Display omitted] •Synthesized sensor BMP is AIEE active.•Chalcone based dual sensor has been synthesized for Zn2+, 4-NP and chloroform detection.•Zn2+ and…”
Get full text