Search Results - "Qvist, Jesper"

HDL cholesterol concentrations and risk of atherosclerotic cardiovascular disease – Insights from randomized clinical trials and human genetics by Kjeldsen, Emilie Westerlin, Thomassen, Jesper Qvist, Frikke-Schmidt, Ruth

“…Through seven decades the inverse association between HDL cholesterol concentrations and risk of atherosclerotic cardiovascular disease (ASCVD) has been…”
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Type-2 diabetes and risk of dementia: observational and Mendelian randomisation studies in 1 million individuals by Thomassen, Jesper Qvist, Tolstrup, Janne Schurmann, Benn, Marianne, Frikke-Schmidt, Ruth

“…In observational studies, type-2 diabetes is associated with increased risk of dementia; however, the causal nature of this association remains unanswered. In…”
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Plasma Concentrations of Magnesium and Risk of Dementia: A General Population Study of 102 648 Individuals by Thomassen, Jesper Qvist, Tolstrup, Janne S, Nordestgaard, Børge G, Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth

“…Low and high concentrations of plasma magnesium are associated with increased risk of future all-cause dementia; however, the underlying reasons remain…”
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Blood Leukocyte Counts in Alzheimer Disease by Luo, Jiao, Thomassen, Jesper Qvist, Nordestgaard, Børge G, Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth

“…Emerging evidence implicates a role for neuroinflammation in Alzheimer disease (AD) pathogenesis, predominantly involving the innate immune system. Blood…”
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Impact of metabolic dysfunction on cognition in humans by Juul Rasmussen, Ida, Qvist Thomassen, Jesper, Frikke-Schmidt, Ruth

“…The current review evaluates the recent literature on the impact of metabolic dysfunction in human cognition, focusing on epidemiological studies and…”
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Update on management of hypokalaemia and goals for the lower potassium level in patients with cardiovascular disease: a review in collaboration with the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy by Krogager, Maria Lukács, Kragholm, Kristian, Thomassen, Jesper Qvist, Søgaard, Peter, Lewis, Basil S, Wassmann, Sven, Baumgartner, Iris, Ceconi, Claudio, Schmidt, Thomas Andersen, Kaski, Juan Carlos, Drexel, Heinz, Semb, Anne Grete, Agewall, Stefan, Niessner, Alexander, Savarese, Gianluigi, Kjeldsen, Keld Per, Borghi, Claudio, Tamargo, Juan, Torp-Pedersen, Christian

“…Abstract Hypokalaemia is common in patients with cardiovascular disease. In this review, we emphasize the importance of tight potassium regulation in patients…”
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IVIVC for fenofibrate immediate release tablets using solubility and permeability as in vitro predictors for pharmacokinetics by Buch, Philipp, Holm, Per, Thomassen, Jesper Qvist, Scherer, Dieter, Branscheid, Robert, Kolb, Ute, Langguth, Peter

“…The goal of this study was to investigate the in vitro-in vivo correlation (IVIVC) for fenofibrate immediate release (IR) tablet formulations based on…”
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Elderly Humans Show Prolonged In Vivo Inflammatory Activity during Pneumococcal Infections by Bruunsgaard, Helle, Skinhøj, Peter, Qvist, Jesper, Pedersen, Bente Klarlund

“…Levels of circulating cytokines were measured in 22 hospitalized patients with pneumococcal infections during the first week after admission, to test for…”
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Ageing is associated with a prolonged fever response in human endotoxemia by Krabbe, K S, Bruunsgaard, H, Hansen, C M, Møller, K, Fonsmark, L, Qvist, J, Madsen, P L, Kronborg, G, Andersen, H O, Skinhøj, P, Pedersen, B K

“…The purpose of this study was to investigate whether an age-associated impaired acute-phase response exists. Nine healthy elderly volunteers (median, 66 years;…”
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Neutrophil counts and cardiovascular disease by Luo, Jiao, Thomassen, Jesper Qvist, Nordestgaard, Børge G, Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth

“…Abstract Background and Aims Anti-inflammatory trials have shown considerable benefits for cardiovascular disease. High neutrophil counts, an easily accessible…”
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Plasma Concentrations of Calcium and Risk of Alzheimer Disease—Observational and Genetic Studies by Thomassen, Jesper Qvist, Nordestgaard, Børge G, Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth

“…Abstract Background Dysregulation of calcium ion homeostasis in neurons is well documented in Alzheimer disease (AD), and high plasma calcium concentrations…”
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C‐reactive protein levels and risk of dementia—Observational and genetic studies of 111,242 individuals from the general population by Hegazy, Sharif H., Thomassen, Jesper Qvist, Rasmussen, Ida Juul, Nordestgaard, Børge G., Tybjærg‐Hansen, Anne, Frikke‐Schmidt, Ruth

“…Introduction Increased plasma levels of C‐reactive protein (CRP) in midlife are associated with increased risk of Alzheimer's disease (AD), whereas in older…”
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Observational and genetic studies of C‐reactive protein levels and risk of Alzheimer's disease by Frikke‐Schmidt, Ruth, Hegazy, Sharif H., Rasmussen, Ida Juul, Nordestgaard, Børge G., Tybjærg‐Hansen, Anne, Thomassen, Jesper Qvist

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Reply to “Mendelian randomization highlights causal association between genetically increased C‐reactive protein levels and reduced Alzheimer's disease risk” by Luo, Jiao, Thomassen, Jesper Qvist, Hegazy, Sharif H., Rasmussen, Ida Juul, Nordestgaard, Børge G., Tybjærg‐Hansen, Anne, Frikke‐Schmidt, Ruth

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Diagnostic value of oligoclonal bands in children: A nationwide population-based cohort study (P4.2-104) by Boesen, Magnus Spangsberg, Born, Alfred Peter, Jensen, Poul Erik Hyldgaard, Sellebjerg, Finn, Blinkenberg, Morten, Lydolph, Magnus Christian, Jørgensen, Mikala Klok, Rosenberg, Lene, Thomassen, Jesper Qvist, Børresen, Malene Landbo

“…Abstract only…”
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Stroke genetics informs drug discovery and risk prediction across ancestries by Mishra, Aniket, Malik, Rainer, Hachiya, Tsuyoshi, Jurgenson, Tuuli, Namba, Shinichi, Posner, Daniel C., Kamanu, Frederick K., Koido, Masaru, Le Grand, Quentin, Shi, Mingyang, He, Yunye, Georgakis, Marios K., Caro, Ilana, Krebs, Kristi, Liaw, Yi-Ching, Vaura, Felix C., Lin, Kuang, Winsvold, Bendik Slagsvold, Srinivasasainagendra, Vinodh, Parodi, Livia, Bae, Hee-Joon, Chauhan, Ganesh, Chong, Michael R, Tomppo, Liisa, Roshchupkin, Gennady V., Habib, Naomi, Jee, Yon Ho, Thomassen, Jesper Qvist, Abedi, Vida, Carcel-Marquez, Jara, Nygaard, Marianne, Leonard, Hampton L., Yang, Chaojie, Yonova-Doing, Ekaterina, Knol, Maria J., Lewis, Adam J.., Judy, Renae L, Ago, Tetsuro, Amouyel, Philippe, Armstrong, Nicole D., Bakker, Mark K., Bartz, Traci M., Bennett, David A., Bis, Joshua C., Bordes, Constance, Borte, Sigrid, Cain, Anael, Ridker, Paul M., Cho, Kelly, Chen, Zhengming, Cruchaga, Carlos, Cole, John W., de Jager, Phil L., de Cid, Rafael, Endres, Matthias, Ferreira, Leslie E., Geerlings, Mirjam I., Gasca, Natalie C., Gudnason, Vilmundur, Hata, Jun, He, Jing, Heath, Alicia K., Ho, Yuk-Lam, Havulinna, Aki S., Hopewell, Jemma .C, Hyacinth, Hyacinth I., Inouye, Michael, Jacob, Mina A., Jeon, Christina E., Jern, Christina, Kamouchi, Masahiro, Keene, Keith L., Kitazono, Takanari, Kittner, Steven J., Konuma, Takahiro, Kumar, Amit, Lacaze, Paul, Launer, Lenore J., Lee, Keon-Joo, Lepik, Kaido, Li, Jiang, Li, Liming, Manichaikul, Ani, Markus, Hugh S., Marston, Nicholas A., Meitinger, Thomas, Mitchell, Braxton D., Montellano, Felipe A., Morisaki, Takayuki, Mosley, Thomas H., Nalls, Mike A., Nordestgaard, Borge G., O'Donnell, Martin J., Okada, Yukinori, Onland-Moret, N. Charlotte, Ovbiagele, Bruce, Peters, Annette, Psaty, Bruce M, Rich, Stephen S.., Rosand, Jonathan

“…Previous genome-wide association studies (GWASs) of stroke - the second leading cause of death worldwide - were conducted predominantly in populations of…”
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Diagnostic Value of Oligoclonal Bands in Children: A Nationwide Population-Based Cohort Study by Boesen, Magnus Spangsberg, Born, Alfred Peter, Jensen, Poul Erik Hyldgaard, Sellebjerg, Finn, Blinkenberg, Morten, Lydolph, Magnus Christian, Jørgensen, Mikala Klok, Rosenberg, Lene, Thomassen, Jesper Qvist, Børresen, Malene Landbo

“…We evaluated the diagnostic value of cerebrospinal fluid oligoclonal bands in individuals less than 18 years of age. In a nationwide population-based setting,…”
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Depression, anxiety and quality-of-life among relatives of patients with severe brain injury: The acute phase by Norup, Anne, Welling, Karen-Lise, Qvist, Jesper, Siert, Lars, Mortensen, Erik L.

“…Primary objective: To investigate the emotional well-being of relatives of patients with a severe brain injury in the acute setting, as well as risk factors…”
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Rare missense variant (R251G) on APOE counterbalances the Alzheimer’s disease risk associated with APOE‐ε4 by Guen, Yann Le, Belloy, Michael E, Grenier‐Boley, Benjamin, de Rojas, Itziar, Castillo, Atahualpa, Jansen, Iris E, Bellenguez, Céline, Dalmasso, Carolina, Küçükali, Fahri, Eger, Sarah J, Álvarez‐Martínez, Victoria, Arosio, Beatrice, Benussi, Luisa, Boland, Anne, Borroni, Barbara, Caffarra, Paolo, Clarimón, Jordi, Daian, Delphine, Daniele, Antonio, Debette, Stéphanie, Dichgans, Martin, Dufouil, Carole, Duzel, Emrah, Galimberti, Daniela, García‐Alberca, Jose María, García‐González, Pablo, Giedraitis, Vilmantas, Grimmer, Timo, Graff, Caroline, Grunblatt, Edna, Hanon, Olivier, Hausner, Lucrezia, Holstege, Henne, Hort, Jakub, Jurgen, Deckert, Kuulasmaa, Teemu, van der Lugt, Aad, Masullo, Carlo, Mecocci, Patrizia, Mehrabian, Shima, de Mendonça, Alexandre, Boada, Mercè, Mir, Pablo, Moebus, Susanne, Moreno, Fermin, Nacmias, Benedetta, Nicolas, Gaël, Papenberg, Goran, Parnetti, Lucilla, Pasquier, Florence, Pastor, Pau, Peters, Oliver, Pijnenburg, Yolande A.L., Piñol‐Ripoll, Gerard, Popp, Julius, Molina, Laura, Puerta, Raquel, Pérez‐Tur, Jordi, Rainero, Innocenzo, Ramakers, Inez H.G.B., Rasmussen, Katrine Laura, Real, Luis Miguel, Riedel‐Heller, Steffi G., Royo, José Luís, Scarmeas, Nikolaos, Scheltens, Philip, Scherbaum, Norbert, Schneider, Anja, Seripa, Davide, Soininen, Hilkka, Solfrizzi, Vincenzo, Spalletta, Gianfranco, Squassina, Alessio, van Swieten, John C, Sanchez‐Valle, Raquel, Tegos, Thomas, Thomassen, Jesper Qvist, Tremolizzo, Lucio, Verhey, Frans R.J., Vyhnalek, Martin, Wiltfang, Jens, He, Zihuai, Napolioni, Valerio, Amouyel, Philippe, Jessen, Frank, Kehoe, Patrick G, van Duijn, Cornelia M, Tsolaki, Magda, Sanchez‐Juan, Pascual, Sleegers, Kristel, Ingelsson, Martin, Rossi, Giacomina, Hiltunen, Mikko, Sims, Rebecca, Ramirez, Alfredo, Andreassen, Ole, Frikke‐Schmidt, Ruth, Williams, Julie, Ruiz, Agustin, Greicius, Michael D

“…Background Despite decades of research, the mechanisms linking APOE to Alzheimer’s disease (AD) remain poorly understood. Finding additional risk variants at…”
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Abstract 40: Causal Aspects of Preeclampsia and Gestational Hypertension for Risk of Future Cardiovascular Diseases by Taageby Nielsen, Sofie, Luo, Jiao, Qvist Thomassen, Jesper, Frikke-Schmidt, Ruth

“…Abstract only Introduction: Preeclampsia is a multifactorial disease and a cause of maternal and neonatal morbidity and mortality. Observational studies show…”
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