Search Results - "Qureshi, Tazeen"
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β-Lactoglobulin-gold nanoparticles interface and its interaction with some anticancer drugs - an approach for targeted drug delivery
Published in Journal of biomolecular structure & dynamics (21-07-2022)“…The protein-nanoparticle interface plays a crucial role in drug binding and stability, in turn enhancing efficacy in targeted drug delivery. In the present…”
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Journal Article -
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Histone deacetylase-6 modulates Tau function in Alzheimer's disease
Published in Biochimica et biophysica acta. Molecular cell research (01-08-2022)“…Alzheimer's disease (AD), one of the major tauopathies, is multifactorial with a massive demand for disease-modifying treatments rather than symptom…”
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Internalization and Endosomal Trafficking of Extracellular Tau in Microglia Improved by α-Linolenic Acid
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…Alzheimer's disease (AD) is distinguished by extracellular accumulation of amyloid-beta plaques and intracellular neurofibrillary tangles of Tau. Pathogenic…”
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Understanding Actin Remodeling in Neuronal Cells Through Podosomes
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…Cytoskeletal dysregulation forms an important aspect of many neurodegenerative diseases such as Alzheimer's disease. Cytoskeletal functions require the dynamic…”
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Journal Article -
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Microglial Uptake of Extracellular Tau by Actin-Mediated Phagocytosis
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…Microglia are scavengers of the brain environment that clear dead cells, debris, and microbes. In Alzheimer's disease, microglia get activated to phagocytose…”
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Macrocyclic peptides derived from AcPHF6 and AcPHF6 to selectively modulate the Tau aggregation
Published in Bioorganic chemistry (01-10-2024)“…[Display omitted] •Designed and synthesized 10 macrocyclic 14-mer peptides based on Tau PHF peptides.•NMR supported antiparallel β-sheet structure in all…”
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Abstract TP361: Recreational Drug Use and Arterial Ischemic Stroke in a Pediatric Cohort
Published in Stroke (1970) (01-02-2020)“…Abstract only Background: Existing literature reports an association between recreational drug use and arterial ischemic stroke (AIS) in adults. Due to recent…”
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Fractioning the Refugee Label–A Case Study of Syrian Refugees in Turkey
Published 01-01-2019“…This research analyzes Turkey‟s national asylum policies to determine if they result in the fractioning of the refugee label – as theorized by Roger Zetter…”
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Dissertation -
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Functionalized Alpha‐lactalbumin Conjugated with Gold Nanoparticle for Targeted Drug Delivery
Published in ChemistrySelect (Weinheim) (14-02-2020)“…The protein‐nanoparticles conjugate has been developed as a targeted drug delivery system which selectively and preferentially delivers the therapeutic agents…”
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Journal Article -
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siRNA targeting Vaccinia virus double-stranded RNA binding protein [E3L] exerts potent antiviral effects
Published in Virology (New York, N.Y.) (10-05-2006)“…The Vaccinia virus gene, E3L, encodes a double-stranded RNA [dsRNA]-binding protein. We hypothesized that, owing to the critical nature of dsRNA in triggering…”
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Journal Article