Search Results - "Qurashi, Samir"

COM902, a novel therapeutic antibody targeting TIGIT augments anti-tumor T cell function in combination with PVRIG or PD-1 pathway blockade by Hansen, Kyle, Kumar, Sandeep, Logronio, Kathryn, Whelan, Sarah, Qurashi, Samir, Cheng, Hsin-Yuan, Drake, Andrew, Tang, Margaret, Wall, Patrick, Bernados, David, Leung, Ling, Ophir, Eran, Alteber, Zoya, Cojocaru, Gady, Galperin, Moran, Frenkel, Masha, White, Mark, Hunter, John, Liang, Spencer C., Kotturi, Maya F.

“…Immune checkpoint inhibitors (ICIs) have emerged as promising therapies for the treatment of cancer. However, existing ICIs, namely PD-(L)1 and CTLA-4…”
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ILT2 and ILT4 Drive Myeloid Suppression via Both Overlapping and Distinct Mechanisms by Tian, Jane, Ashique, Amir M, Weeks, Sabrina, Lan, Tian, Yang, Hong, Chen, Hung-I Harry, Song, Christina, Koyano, Kikuye, Mondal, Kalyani, Tsai, Daniel, Cheung, Isla, Moshrefi, Mehrdad, Kekatpure, Avantika, Fan, Bin, Li, Betty, Qurashi, Samir, Rocha, Lauren, Aguayo, Jonathan, Rodgers, Col, Meza, Marchelle, Heeke, Darren, Medfisch, Sara M, Chu, Chun, Starck, Shelley, Basak, Nandini Pal, Sankaran, Satish, Malhotra, Mohit, Crawley, Suzanne, Tran, Thomas-Toan, Duey, Dana Y, Ho, Carmence, Mikaelian, Igor, Liu, Wenhui, Rivera, Lee B, Huang, Jiawei, Paavola, Kevin J, O'Hollaren, Kyle, Blum, Lisa K, Lin, Vicky Y, Chen, Peirong, Iyer, Anjushree, He, Sisi, Roda, Julie M, Wang, Yan, Sissons, James, Kutach, Alan K, Kaplan, Daniel D, Stone, Geoffrey W

“…Solid tumors are dense three-dimensional (3D) multicellular structures that enable efficient receptor-ligand trans interactions via close cell-cell contact…”
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Abstract 664: Immune inhibitory receptors ILT2 and ILT4 exhibit both distinct and overlapping biology in vitro and in vivo by Tian, Jane, Qurashi, Samir, Song, Christina, Rocha, Lauren, Mondal, Kalyani, Crawley, Suzanne, Medfisch, Sara, Chen, Peirong Krisney, Roda, Julie, Sitrin, Jon, Ho, Carmence, Aguayo, Jonathan, Rivera, Lee, Huang, Jiawei, Lin, Vicky, Shen, David, Wang, Yan, Tian, Hui, Kutach, Alan, Sissons, James, Kaplan, Daniel D., Stone, Geoffrey W.

“…Background: Immune suppression in the tumor microenvironment is known to contribute to tumor immune evasion. ILT2 (aka LILRB1) and ILT4 (aka LILRB2) are…”
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