Search Results - "Qun Pan"
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Effect of Ca(OH)2 on shrinkage characteristics and microstructures of alkali-activated slag concrete
Published in Construction & building materials (30-06-2018)“…•Use of Ca(OH)2 coarsens AAS concrete pores.•Autogenous and drying shrinkage were significantly reduced by adding Ca(OH)2.•Ca-rich hydration products were…”
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2
Widespread intron retention in mammals functionally tunes transcriptomes
Published in Genome research (01-11-2014)“…© 2014 Braunschweig et al.; Published by Cold Spring Harbor Laboratory Press. This article is distributed exclusively by Cold Spring Harbor Laboratory Press…”
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3
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
Published in Nature genetics (01-12-2008)“…We carried out the first analysis of alternative splicing complexity in human tissues using mRNA-Seq data. New splice junctions were detected in ∼20% of…”
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4
Deciphering the splicing code
Published in Nature (London) (06-05-2010)“…Alternative splicing has a crucial role in the generation of biological complexity, and its misregulation is often involved in human disease. Here we describe…”
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Regulation of Alternative Splicing by Histone Modifications
Published in Science (American Association for the Advancement of Science) (19-02-2010)“…Alternative splicing of pre-mRNA is a prominent mechanism to generate protein diversity, yet its regulation is poorly understood. We demonstrated a direct role…”
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Regulation of alternative splicing by the core spliceosomal machinery
Published in Genes & development (15-02-2011)“…Alternative splicing (AS) plays a major role in the generation of proteomic diversity and in gene regulation. However, the role of the basal splicing machinery…”
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The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation
Published in Molecular cell (24-09-2010)“…Alternative splicing (AS) of pre-mRNA is utilized by higher eukaryotes to achieve increased transcriptome and proteomic complexity. The serine/arginine (SR)…”
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The Evolutionary Landscape of Alternative Splicing in Vertebrate Species
Published in Science (American Association for the Advancement of Science) (21-12-2012)“…How species with similar repertoires of protein-coding genes differ so markedly at the phenotypic level is poorly understood. By comparing organ transcriptomes…”
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Intelligent diagnosis of northern corn leaf blight with deep learning model
Published in Journal of Integrative Agriculture (01-04-2022)“…Maize (Zea mays L.), also known as corn, is the third most cultivated crop in the world. Northern corn leaf blight (NCLB) is a globally devastating maize…”
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10
MicroRNA signature and regulatory functions in the endometrium during normal and disease states
Published in Seminars in reproductive medicine (01-11-2008)“…During the menstrual cycle, human endometrium undergoes extensive cyclic morphologic and biochemical modifications in preparation for embryo implantation…”
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Tissue-Specific Alternative Splicing Remodels Protein-Protein Interaction Networks
Published in Molecular cell (29-06-2012)“…Alternative splicing plays a key role in the expansion of proteomic and regulatory complexity, yet the functions of the vast majority of differentially spliced…”
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12
Pravastatin promotes type 2 diabetes vascular calcification through activating intestinal Bacteroides fragilis to induce macrophage M1 polarization
Published in Journal of diabetes (01-06-2024)“…Background Pravastatin is an oral lipid‐lowering drug, commonly used by patients with diabetes that is positively correlated with the occurrence of vascular…”
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13
Extracellular vesicles of Bacteroides fragilis regulated macrophage polarization through promoted Sema7a expression
Published in Microbial pathogenesis (01-02-2024)“…Abnormal activation of macrophage and gut Bacteroides fragilis (BF) are the important induction factors in the occurrence of type 2 diabetes (T2D) and vascular…”
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14
The expression profile of micro-RNA in endometrium and endometriosis and the influence of ovarian steroids on their expression
Published in Molecular human reproduction (01-11-2007)“…MicroRNAs (miRNAs), through mRNA degradation or repression, act as key regulator of gene expression. Our aim was to identify specific miRNAs that are expressed…”
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15
Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation
Published in Genome research (01-03-2011)“…The rate of RNA polymerase II (Pol II) elongation can influence splice site selection in nascent transcripts, yet the extent and physiological relevance of…”
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An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming
Published in Cell (30-09-2011)“…Alternative splicing (AS) is a key process underlying the expansion of proteomic diversity and the regulation of gene expression. Here, we identify an…”
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A germline mutation in SRRM2, a splicing factor gene, is implicated in papillary thyroid carcinoma predisposition
Published in Scientific reports (02-07-2015)“…Papillary thyroid carcinoma (PTC) displays strong but so far largely uncharacterized heritability. Here we studied genetic predisposition in a family with six…”
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Cervical spondylotic internal jugular venous compression syndrome
Published in CNS neuroscience & therapeutics (01-01-2020)“…Aims This study aimed to identify the clinical profiles of cervical spondylosis‐related internal jugular vein stenosis (IJVS) comprehensively. Methods A total…”
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Correction: An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing
Published in PLoS pathogens (09-04-2024)“…[This corrects the article DOI: 10.1371/journal.ppat.1008307.]…”
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Understanding jugular venous outflow disturbance
Published in CNS neuroscience & therapeutics (01-06-2018)“…Summary Extracranial venous abnormalities, especially jugular venous outflow disturbance, were originally viewed as nonpathological phenomena due to a lack of…”
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