Search Results - "Qun, Sen"
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Microglia govern the extinction of acute stress-induced anxiety-like behaviors in male mice
Published in Nature communications (10-01-2024)“…Anxiety-associated symptoms following acute stress usually become extinct gradually within a period of time. However, the mechanisms underlying how individuals…”
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Ginsenoside Rg1 attenuates cerebral ischemia-reperfusion injury due to inhibition of NOX2-mediated calcium homeostasis dysregulation in mice
Published in Journal of ginseng research (01-07-2022)“…The incidence of ischemic cerebrovascular disease is increasing in recent years and has been one of the leading causes of neurological dysfunction and death…”
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Neutrophil-To-Lymphocyte Ratio Predicts 3-Month Outcome of Acute Ischemic Stroke
Published in Neurotoxicity research (01-04-2017)“…Increasing evidences have demonstrated that inflammation is involved in the mechanisms of acute ischemic stroke (AIS). As an important and easy-to-measure…”
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A microglial activation cascade across cortical regions underlies secondary mechanical hypersensitivity to amputation
Published in Cell reports (Cambridge) (27-02-2024)“…Neural mechanisms underlying amputation-related secondary pain are unclear. Using in vivo two-photon imaging, three-dimensional reconstruction, and fiber…”
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Serum beta2-microglobulin levels are highly associated with the risk of acute ischemic stroke
Published in Scientific reports (03-05-2019)“…Inflammation is considered an important mechanism of cell death or survival after ischemic stroke. As an important marker of inflammation, the role of…”
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Neutrophil-to-Lymphocyte Ratios Are Closely Associated With the Severity and Course of Non-mild COVID-19
Published in Frontiers in immunology (02-09-2020)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is spreading worldwide. Measuring the prevention and control of the disease has become a…”
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Protective effects of ginsenoside Rg1 on neuronal senescence due to inhibition of NOX2 and NLRP1 inflammasome activation in SAMP8 mice
Published in Journal of functional foods (01-02-2020)“…With aging of population, aging-related neurodegenerative diseases have become a major public health concern. Oxidative stress and neuroinflammation have been…”
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β2-Microglobulin is a Novel and Reliable Biomarker for Predicting Ischemic Stroke Recurrence: A Prospective Cohort Study
Published in Frontiers in pharmacology (17-06-2022)“…Immune and inflammatory mechanisms play key roles in the development and outcome of acute ischemic stroke (AIS). β2-Microglobulin (β2M) is the light chain of…”
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Serum β2-Microglobulin Is Closely Associated With the Recurrence Risk and 3-Month Outcome of Acute Ischemic Stroke
Published in Frontiers in neurology (09-01-2020)“…Inflammation plays a significant role in the pathogenesis of acute ischemic stroke (AIS). The role of β2-microglobulin (β2M) as a potential initiator of the…”
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Ginsenoside Rg1 attenuates cerebral ischemia-reperfusion injury due to inhibition of NOX2-mediated calcium homeostasis dysregulation in mice
Published in Journal of ginseng research (2022)“…Background: The incidence of ischemic cerebrovascular disease is increasing in recent years and has been one of the leading causes of neurological dysfunction…”
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Trpc6 knockout improves behavioral dysfunction and reduces Aβ production by inhibiting CN-NFAT1 signaling in T2DM mice
Published in Experimental neurology (01-05-2023)“…As the prevalence of diabetes and health awareness increase, type 2 diabetes mellitus -associated cognitive dysfunction is receiving increasing attention…”
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A noradrenergic pathway for the induction of pain by sleep loss
Published in Current biology (17-06-2024)“…An epidemic of sleep loss currently affects modern societies worldwide and is implicated in numerous physiological disorders, including pain sensitization,…”
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Endovascular treatment for acute basilar artery occlusion: A multicenter randomized controlled trial (ATTENTION)
Published in International journal of stroke (01-08-2022)“…Background and hypothesis: Recently, two multicenter randomized controlled trials (RCT) failed to show a significantly beneficial effect of endovascular…”
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Up-regulation of HCN2 channels in a thalamocortical circuit mediates allodynia in mice
Published in National science review (01-02-2023)“…Chronic pain is a significant problem that afflicts individuals and society, and for which the current clinical treatment is inadequate. In addition, the…”
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Gene polymorphisms and circulating levels of the TNF-alpha are associated with ischemic stroke: A meta-analysis based on 19,873 individuals
Published in International immunopharmacology (01-10-2019)“…Numerous studies have investigated associations of gene polymorphisms and circulating levels of TNF-α with ischemic stroke (IS), but the results were…”
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Ginkgo biloba extract improves cognitive function and increases neurogenesis by reducing Aβ pathology in 5×FAD mice
Published in American journal of translational research (2021)“…Previous studies have indicated that the generation of newborn hippocampal neurons is impaired in the early phase of Alzheimer's disease (AD). A potential…”
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A novel dominant-negative mutation of the CSF1R gene causes adult-onset leukoencephalopathy with axonal spheroids and pigmented glia
Published in American journal of translational research (01-01-2019)“…Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a rare autosomal dominant disorder that is caused by mutations in the…”
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The Role of Hyperdense Basilar Artery Sign in Predicting Outcome of Acute Basilar Artery Occlusion within Twelve Hours of Onset
Published in World neurosurgery (01-03-2024)“…The correlation between hyperdense basilar artery sign (HDBAS) and outcome after acute basilar artery occlusion (ABAO) is debated. Our objective was to…”
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Prognosis of hepatocellular carcinoma with bile duct tumor thrombus after R0 resection:a matched study
Published in Hepatobiliary & pancreatic diseases international (01-12-2016)“…BACKGROUND: Hepatocellular carcinoma (HCC) with bile duct tumor thrombus (BDTT) is rare. The present study aimed to determine post-surgical prognoses in HCC…”
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