Search Results - "Quiroga, Maite P."

Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance by Kurtova, Antonina V., Balakrishnan, Kumudha, Chen, Rong, Ding, Wei, Schnabl, Susanne, Quiroga, Maite P., Sivina, Mariela, Wierda, William G., Estrov, Zeev, Keating, Michael J., Shehata, Medhat, Jäger, Ulrich, Gandhi, Varsha, Kay, Neil E., Plunkett, William, Burger, Jan A.

“…Marrow stromal cells (MSCs) provide important survival and drug resistance signals to chronic lymphocytic leukemia (CLL) cells, but current models to analyze…”
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Influence of bone marrow stromal microenvironment on forodesine-induced responses in CLL primary cells by Balakrishnan, Kumudha, Burger, Jan A., Quiroga, Maite P., Henneberg, Marina, Ayres, Mary L., Wierda, William G., Gandhi, Varsha

“…Forodesine, a purine nucleoside phosphorylase inhibitor, displays in vitro activity in chronic lymphocytic leukemia (CLL) cells in presence of dGuo, which is…”
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High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation by Burger, Jan A., Quiroga, Maite P., Hartmann, Elena, Bürkle, Andrea, Wierda, William G., Keating, Michael J., Rosenwald, Andreas

“…In lymphatic tissues, chronic lymphocytic leukemia (CLL) cells are interspersed with CD68+ nurselike cells (NLCs), T cells, and other stromal cells that…”
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B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406 by Quiroga, Maite P., Balakrishnan, Kumudha, Kurtova, Antonina V., Sivina, Mariela, Keating, Michael J., Wierda, William G., Gandhi, Varsha, Burger, Jan A.

“…Antigenic stimulation through the B-cell antigen receptor (BCR) is considered to promote the expansion of chronic lymphocytic leukemia (CLL) B cells. The…”
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BCR-Mediated Decrease of CXCR4 and CD62L in CLL – Letter by Quiroga, Maite P., Burger, Jan A.

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The Immunophenotype Signature CD49d+CD38+ Identifies Chronic Lymphocytic Leukemia Cases with a Higher Potential for Migration Beneath Marrow Stromal Cells by Kurtova, Antonina, Sivina, Mariela, Quiroga, Maite P., Wierda, William G., Keating, Michael J., Burger, Jan A.

“…Abstract 356▪▪This icon denotes an abstract that is clinically relevant. Adhesion of chronic lymphocytic leukemia (CLL) cells to stromal cells in the marrow…”
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Standardizing Co-Culture Conditions Between Chronic Lymphocytic Leukemia Cells and Marrow Stromal Cells: Towards a Reliable and Reproducible System to Assess Cell Adhesion-Mediated Drug Resistance by Kurtova, Antonina, Quiroga, Maite P., Wierda, William G., Keating, Michael, Burger, Jan A.

“…Contact between chronic lymphocytic leukemia (CLL) cells and accessory stromal cells in tissue microenvironments is considered to play a major role in…”
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Inhibition of BCR Signaling Using the SYK Inhibitor R406 Antagonizes Migratory and Pro-Survival Responses in CLL Cells by Quiroga, Maite P., Kurtova, Antonina, Wierda, William, Keating, Michael, Burger, Jan A.

“…Disrupting B cell receptor- (BCR-) induced signaling by inhibiting the spleen tyrosine kinase (SYK) represents a novel therapeutic approach in CLL. R406 is an…”
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BCR-mediated decrease of CXCR4 and CD62L in CLL by Quiroga, Maite P, Burger, Jan A

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