Search Results - "Quiroga, G. A."
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Using phosphine ligands with a biological role to modulate reactivity in novel platinum complexes
Published in Royal Society open science (01-02-2018)“…Three platinum complexes with cis and trans configuration cis-[Pt(TCEP)2Cl2], cis-[Pt(tmTCEP)2Cl2] and trans-[Pt(TCEP)2Cl2], where TCEP is…”
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Understanding trans platinum complexes as potential antitumor drugs beyond targeting DNA
Published in Journal of inorganic biochemistry (01-09-2012)“…This focused review is devoted to our advances in developing trans platinum complexes as antitumoral complexes, in particular those bearing aliphatic amines…”
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Novel Tetranuclear Orthometalated Complexes of Pd(II) and Pt(II) Derived from p-Isopropylbenzaldehyde Thiosemicarbazone with Cytotoxic Activity in cis-DDP Resistant Tumor Cell Lines. Interaction of These Complexes with DNA
Published in Journal of medicinal chemistry (23-04-1998)“…The reaction of p-isopropylbenzaldehyde thiosemicarbazone [p-is.TSCN], 1, with palladium(II) acetate and potassium tetrachloroplatinate yielded two tetrameric…”
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Regulatory effects of miR-19a on MAD2 expression and tumorigenesis in gastric cancer
Published in Genes & diseases (01-07-2023)Get full text
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Synthesis, characterization and DNA modification induced by a novel Pt(IV)-bis(monoglutarate) complex which induces apoptosis in glioma cells
Published in Chemico-biological interactions (29-01-1999)“…Programmed cell death or apoptosis is a mechanism for the elimination of cells that occurs not only in physiological processes but also in drug-induced tumor…”
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Structural Characterization, DNA Interactions, and Cytotoxicity of New Transplatin Analogues Containing One Aliphatic and One Planar Heterocyclic Amine Ligand
Published in Journal of medicinal chemistry (20-04-2006)“…We report in the present work new analogues of clinically ineffective transplatin in which one ammine group was replaced by aliphatic and the other by a planar…”
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Improvement in health care quality for patients from the thoracic/chest pain unit in a regional hospital
Published in Revista de calidad asistencial (01-07-2011)“…The evaluation of an improvement cycle in patients suffering thoracic/chest pain in hospital emergencies, especially in those who could benefit from the early…”
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High risk dyslipidemia: can we predict early coronary disease?
Published in European journal of preventive cardiology (24-05-2023)“…Abstract Funding Acknowledgements Type of funding sources: None. Introduction The AHA/ACC guidelines on the management of blood cholesterol (2013 and 2018)…”
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Usefulness of impedanciometry for the assessment of obesity in a high risk dyslipidemia screening unit
Published in European journal of preventive cardiology (24-05-2023)“…Abstract Funding Acknowledgements Type of funding sources: None. Introduction Residual risk is related to future events in already treated patients. In…”
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Consequences of diabetes and high-risk dyslipidemia
Published in European journal of preventive cardiology (24-05-2023)“…Abstract Funding Acknowledgements Type of funding sources: None. Introduction Diabetic patients develop both, microvascular and macrovascular long-term…”
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Preparation, characterization and cytotoxic activity of new compounds trans-[PtCl 2NH 3(3-(hydroxymethyl)-pyridine)] and trans-[PtCl 2NH 3(4-(hydroxymethyl)-pyridine)]
Published in Polyhedron (15-11-2003)“…We report the synthesis, characterization and cytotoxic assays of new trans-platinum compounds, trans-[PtCl 2NH 3(3-(hydroxymethyl)-pyridine)] and trans-[PtCl…”
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Predictors of cardiovascular disease in a familial hypercholesterolemia unit
Published in European journal of preventive cardiology (24-05-2023)“…Abstract Funding Acknowledgements Type of funding sources: None. Introduction Screening and cascade screening for familial hypercholesterolemia (FH) is advised…”
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Gender differences low-density lipoprotein cholesterol reduction with PCSK9 inhibitors in real world patients
Published in European heart journal (12-10-2021)“…Abstract Background Monoclonal antibodies that inhibit the proprotein convertase subtilisin/kexin type 9 (PCSK9) reduce low-density lipoprotein cholesterol…”
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Synthesis and characterization of Pd(II) and Pt(II) complexes of p-isopropylbenzaldehyde N-protected thiosemicarbazones. Cytotoxic activity against ras-transformed cells
Published in Journal of inorganic biochemistry (15-07-1999)“…Cytotoxicity tests in tumor cells sensitive to cis-DDP (HL-60, JURKAT, Hela and 3T3) and in tumor cells transformed by ras oncogenes and resistant to cis-DDP…”
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Exergy analysis of a combined power and cooling cycle
Published in Applied thermal engineering (02-10-2013)“…This paper presents a comprehensive exergy analysis of a combined power and cooling cycle which combines a Rankine and absorption refrigeration cycle by using…”
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Palladated and platinated complexes derived from phenylacetaldehyde thiosemicarbazone with cytotoxic activity in cis-DDP resistant tumor cells. Formation of DNA interstrand cross-links by these complexes
Published in Journal of inorganic biochemistry (01-05-1998)“…In the present paper we report the synthesis and characterization by 1H NMR, 13C NMR and heteronuclear 2D NMR spectroscopies of two new metallic complexes…”
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Binuclear chloro-bridged palladated and platinated complexes derived from p-isopropylbenzaldehyde thiosemicarbazone with cytotoxicity against cisplatin resistant tumor cell lines
Published in Journal of inorganic biochemistry (01-03-1998)“…Two novel dimeric chloro-bridged complexes [Pd ( p-is.TSCN) (μ-Cl)] 2, 2, and [Pt ( p-is.TSCN)(μ-C1)] 2, 3, where p-is. TSCN = p-isopropylbenzaldehyde…”
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Evaluation of distributed generation impacts on distribution networks under different penetration scenarios
Published in 2015 IEEE PES Innovative Smart Grid Technologies Latin America (ISGT LATAM) (01-10-2015)“…This paper presents a methodology and a computational tool developed for the assessment of the impacts caused by photovoltaic and wind generators, up to 100…”
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Conference Proceeding -
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A cycloplatinated compound of p-isopropylbenzaldehyde thiosemicarbazone and its chloro-bridged derivative induce apoptosis in cis-DDP resistant cells which overexpress the H- ras oncogene
Published in Journal of inorganic biochemistry (01-04-1999)“…cis-Diamminedichloroplatinum(II) ( cis-DDP) is a widely used antitumour drug which produces important damage on the DNA inducing apoptosis in several cell…”
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