Search Results - "Quiroga, Adoracion"

Novel clioquinol and its analogous platinum complexes: importance, role of the halogen substitution and the hydroxyl group of the ligand by Martín Santos, Cecilia, Cabrera, Silvia, Ríos-Luci, Carla, Padrón, José M, López Solera, Isabel, Quiroga, Adoración G, Medrano, María A, Navarro-Ranninger, Carmen, Alemán, José

“…In this communication, we present the synthesis of new platinum complexes based on hydroxyquinoline ligands. We demonstrate the importance and the role of the…”
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Proving the Antimicrobial Therapeutic Activity on a New Copper–Thiosemicarbazone Complex by Fabra, David, Amariei, Georgiana, Ruiz-Camino, Daniel, Matesanz, Ana I., Rosal, Roberto, Quiroga, Adoracion G., Horcajada, Patricia, Hidalgo, Tania

“…The misuse and overdose of antimicrobial medicines are fostering the emergence of novel drug-resistant pathogens, providing negative repercussions not only on…”
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A select thiosemicarbazone copper(II) complex induces apoptosis in gastric cancer and targets cancer stem cells reducing pluripotency markers by Fabra, David, Melones-Herrero, Jorge, Velazquez-Gutierrez, Javier, Matesanz, Ana I., Aliseda, Patricia D., Figueiras, Sofia, Aguilar-Rico, Francisco, Calés, Carmela, Sánchez-Pérez, Isabel, Quiroga, Adoracion G.

“…Copper(II)-based complexes are promising candidates as anti-cancer agents due to their ability to target cancer cells. Here we describe the synthesis and…”
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New Platinum(II) Triazole Thiosemicarbazone Complexes: Analysis of Their Reactivity and Potential Antitumoral Action by Matesanz, Ana I., Herrero, Jorge M., Faraco, Eva J., Cubo, Leticia, Quiroga, Adoracion G.

“…The synthesis and characterization of three new platinum complexes, with 3,5‐diacetyl‐1,2,4‐triazole bis(4‐N‐isopropylthiosemicarbazone) as a ligand, are…”
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Increasing DNA reactivity and in vitro antitumor activity of trans diiodido Pt(II) complexes with UVA light by Navas, Francisco, Perfahl, Stefanie, Garino, Claudio, Salassa, Luca, Novakova, Olga, Navarro-Ranninger, Carmen, Bednarski, Patrick J., Malina, Jaroslav, Quiroga, Adoración.G.

“…Trans diiodido platinum(II) complexes bearing the same as well as different aliphatic amines (mixed-amines) have interesting biological activity; cytotoxicity…”
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Dithiobiureas Palladium(II) complexes' studies: From their synthesis to their biological action by Herrero, Jorge M., Fabra, David, Matesanz, Ana I., Hernández, Carolina, Sánchez-Pérez, Isabel, Quiroga, Adoracion G.

“…Dithiobiureas coordination chemistry towards palladium (II) ions and their possible application is presented and discussed…”
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Versatile Route to trans-Platinum(II) Complexes via Manipulation of a Coordinated 3‑(Pyridin-3-yl)propanoic Acid Ligand by Cabrera, Silvia, Navas, Francisco, Matesanz, Ana I, Maroto, Marta, Riedel, Tina, Dyson, Paul J, Quiroga, Adoracion G

“…We describe the direct coupling of alcohols and amines to a 3-(pyridin-3-yl)­propanoic acid ligand coordinated to a Pt­(II) to afford ester and amide…”
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Reactions of a tetranuclear Pt-thiosemicarbazone complex with model proteins by Marzo, Tiziano, Navas, Francisco, Cirri, Damiano, Merlino, Antonello, Ferraro, Giarita, Messori, Luigi, Quiroga, Adoracion G.

“…The tetranuclear Pt complex (PtL)4 (where L2− is the anion derived from para-isopropyl thiosemicarbazone) was first described in A.G. Quiroga et al., J. Med…”
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Peculiar Features in the Crystal Structure of the Adduct Formed between cis-PtI2(NH3)2 and Hen Egg White Lysozyme by Messori, Luigi, Marzo, Tiziano, Gabbiani, Chiara, Valdes, Amparo A, Quiroga, Adoracion G, Merlino, Antonello

“…The reactivity of cis-diamminediiodidoplatinum(II), cis-PtI2(NH3)2, the iodo analogue of cisplatin, with hen egg white lysozyme (HEWL) was investigated by…”
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XPA, XPC, and XPD Modulate Sensitivity in Gastric Cisplatin Resistance Cancer Cells by Pajuelo-Lozano, Natalia, Bargiela-Iparraguirre, Jone, Dominguez, Gemma, Quiroga, Adoracion G, Perona, Rosario, Sanchez-Perez, Isabel

“…Cisplatin is an election drug widely used in clinic for the treatment of advanced gastric cancer. However, the heterogeneity of the gastric tumors and its…”
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Interactions between Anticancer trans-Platinum Compounds and Proteins: Crystal Structures and ESI-MS Spectra of Two Protein Adducts of trans-(Dimethylamino)(methylamino)dichloridoplatinum(II) by Messori, Luigi, Marzo, Tiziano, Michelucci, Elena, Russo Krauss, Irene, Navarro-Ranninger, Carmen, Quiroga, Adoracion G, Merlino, Antonello

“…The adducts formed between trans-(dimethylamino)(methylamino)dichloridoplatinum(II), [t-PtCl2(dma)(ma)], and two model proteins, i.e., hen egg white lysozyme…”
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Nonconventional trans‐Platinum Complexes Functionalized with RDG Peptides: Chemical and Cytototoxicity Studies by Medrano, Maria Angeles, Morais, Maurício, Ferreira, Vera F. C., Correia, João D. G., Paulo, António, Santos, Isabel, Navarro‐Ranninger, Carmen, Valdes, Amparo Alvarez, Casini, Angela, Mendes, Filipa, Quiroga, Adoración G.

“…In order for platinum complexes to target cancer cells, trans‐PtII or trans‐PtIV complexes were bioconjugated to the cyclic peptide cRGDfK (cRGD), which has an…”
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Two Different Thiosemicarbazone Tauto‐Conformers Coordinate to Palladium (II). Stability and Biological Studies of the Final Complexes by Fabra, David, Matesanz, Ana I., Herrero, Jorge M., Alvarez, Cristina, Balsa, Lucia M., Leon, Ignacio E., Quiroga, Adoracion G.

“…Thiosemicarbazone moiety is a valuable scaffold for the synthesis of metallic complexes with anticancer purposes, when bearing N‐heterocyclic the final…”
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Oxidation of anticancer Pt(II) complexes with monodentate phosphane ligands: towards stable but active Pt(IV) prodrugs by Medrano, María Ángeles, Álvarez-Valdés, Amparo, Perles, Josefina, Lloret-Fillol, Julio, Muñoz-Galván, Sandra, Carnero, Amancio, Navarro-Ranninger, Carmen, Quiroga, Adoración G

“…The synthesis, characterization and cytotoxicity studies of two novel platinum(IV) complexes, trans-PtCl4(dma)(PPh3), 1, and trans-PtCl4(ipa)(PPh3), 2, where…”
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Non-classical structures among current platinum complexes with potential as antitumor drugs by G Quiroga, Adoracion

“…The potential and limitations of the non classical metallodrugs with platinum as metal are discussed in this section, focusing not only in their design but in…”
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The preparation and characterization of trans-platinum(IV) complexes with unusually high cytotoxicity by Cubo, Leticia, Hambley, Trevor W, Sanz Miguel, Pablo J, Carnero, Amancio, Navarro-Ranninger, Carmen, Quiroga, Adoración G

“…The physical and biological properties have been determined for three Pt(IV) complexes with trans amine ligands:…”
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Novel structures of platinum complexes bearing N‑bisphosphonates and study of their biological properties by Alvarez-Valdes, Amparo, Matesanz, Ana I., Perles, Josefina, Fernandes, Célia, Correia, João D.G., Mendes, Filipa, Quiroga, Adoracion G.

“…Novel bisphosphonate platinum complexes: [Pt(isopropylamine)2(BP)]NO3 (BP = pamidronate and alendronate) have been synthesized and characterized. Their…”
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An androgenic steroid delivery vector that imparts activity to a non-conventional platinum(II) metallo-drug by Huxley, Martin, Sanchez-Cano, Carlos, Browning, Michael J, Navarro-Ranninger, Carmen, Quiroga, Adoracion G, Rodger, Alison, Hannon, Michael J

“…A range of androgen conjugates with non-conventional platinum(II) complexes have been synthesised with the aim of targeting tumour cells since many display…”
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New trans-Platinum Drugs with Phosphines and Amines as Carrier Ligands Induce Apoptosis in Tumor Cells Resistant to Cisplatin by Ramos-Lima, Francisco J, Quiroga, Adoración G, García-Serrelde, Beatriz, Blanco, Fernando, Carnero, Amancio, Navarro-Ranninger, Carmen

“…Cisplatin resistance observed in some human tumors has prompted research in platinum derivatives that can circumvent this effect. Despite initial works…”
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Synthesis, cytotoxicity, DNA interaction and cell cycle studies of trans-diiodophosphine Pt(II) complexes by Medrano, Angeles, Dennis, Stephen M, Alvarez-Valdés, Amparo, Perles, Josefina, McGregor Mason, Tracey, Quiroga, Adoracion G

“…Platinum complexes, bearing aliphatic amines and phosphine ligands in trans configuration with iodide as leaving groups, are synthesized and characterized. The…”
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