Search Results - "Quinton, A."

The Role of LIN28- let-7 -ARID3B Pathway in Placental Development by Ali, Asghar, Bouma, Gerrit J, Anthony, Russell V, Winger, Quinton A

“…Placental disorders are a major cause of pregnancy loss in humans, and 40-60% of embryos are lost between fertilization and birth. Successful embryo…”
Get full text

MicroRNA-mRNA Networks in Pregnancy Complications: A Comprehensive Downstream Analysis of Potential Biomarkers by Ali, Asghar, Hadlich, Frieder, Abbas, Muhammad W, Iqbal, Muhammad A, Tesfaye, Dawit, Bouma, Gerrit J, Winger, Quinton A, Ponsuksili, Siriluck

“…Pregnancy complications are a major cause of fetal and maternal morbidity and mortality in humans. The majority of pregnancy complications initiate due to…”
Get full text

Cell-Secreted Vesicles in Equine Ovarian Follicular Fluid Contain miRNAs and Proteins: A Possible New Form of Cell Communication Within the Ovarian Follicle by DA SILVEIRA, Juliano C, VEERAMACHANENI, D. N. Rao, WINGER, Quinton A, CARNEVALE, Elaine M, BOUMA, Gerrit J

“…Proper cell communication within the ovarian follicle is critical for the growth and maturation of a healthy oocyte that can be fertilized and develop into an…”
Get full text

LIN28‐let‐7 axis regulates genes in immortalized human trophoblast cells by targeting the ARID3B‐complex by Ali, Asghar, Anthony, Russell V., Bouma, Gerrit J., Winger, Quinton A.

“…Abnormal placental development is one of the main etiological factors for intrauterine growth restriction (IUGR). Here, we show that LIN28A and LIN28B are…”
Get full text

Cell-secreted vesicles containing microRNAs as regulators of gamete maturation by da Silveira, Juliano C, de Ávila, Ana Clara F C M, Garrett, Hannah L, Bruemmer, Jason E, Winger, Quinton A, Bouma, Gerrit J

“…Mammalian gamete maturation requires extensive signaling between germ cells and their surrounding somatic cells. In the ovary, theca cells, mural granulosa…”
Get full text

Comparative transmission of bacteria from Artemia salina and Brachionus plicatilis to the cnidarian Nematostella vectensis by Krueger, Quinton A, Shore, Madisun H, Reitzel, Adam M

“…ABSTRACT The microbial community associated with animals (microbiome) is essential for development, physiology, and health of host organisms. A critical step…”
Get full text

Tropical Cyclones Downscaled from Simulations of the Last Glacial Maximum by Lawton, Quinton A., Korty, Robert L., Zamora, Ryan A.

“…The tracks, intensities, and other properties of tropical cyclones downscaled from three models’ simulations of the Last Glacial Maximum (LGM) are analyzed and…”
Get full text

The detection of germline and somatic BRCA1/2 genetic variants through parallel testing of patients with high‐grade serous ovarian cancer: a national retrospective audit by Frugtniet, B, Morgan, S, Murray, A, Palmer‐Smith, S, White, R, Jones, R, Hanna, L, Fuller, C, Hudson, E, Mullard, A, Quinton, AE

“…Objective To determine the frequency of germline and somatic pathogenic BRCA1 and BRCA2 variants in patients with high‐grade serous ovarian cancer tested by…”
Get full text

Fetal Hypoglycemia Induced by Placental SLC2A3 -RNA Interference Alters Fetal Pancreas Development and Transcriptome at Mid-Gestation by Kennedy, Victoria C, Lynch, Cameron S, Tanner, Amelia R, Winger, Quinton A, Gad, Ahmed, Rozance, Paul J, Anthony, Russell V

“…Glucose, the primary energy substrate for fetal oxidative processes and growth, is transferred from maternal to fetal circulation down a concentration gradient…”
Get full text

Impact of Placental SLC2A3 Deficiency during the First-Half of Gestation by Lynch, Cameron S, Kennedy, Victoria C, Tanner, Amelia R, Ali, Asghar, Winger, Quinton A, Rozance, Paul J, Anthony, Russell V

“…In the ruminant placenta, glucose uptake and transfer are mediated by facilitative glucose transporters SLC2A1 (GLUT1) and SLC2A3 (GLUT3). SLC2A1 is located on…”
Get full text

Regulation of ACVR1 and ID2 by cell-secreted exosomes during follicle maturation in the mare by da Silveira, Juliano C, Carnevale, Elaine M, Winger, Quinton A, Bouma, Gerrit J

“…Ovarian follicle growth and maturation requires extensive communication between follicular somatic cells and oocytes. Recently, intercellular cell…”
Get full text

Shifting perspectives from "oncogenic" to oncofetal proteins; how these factors drive placental development by West, Rachel C, Bouma, Gerrit J, Winger, Quinton A

“…Early human placental development strongly resembles carcinogenesis in otherwise healthy tissues. The progenitor cells of the placenta, the cytotrophoblast,…”
Get full text

CSH RNA Interference Reduces Global Nutrient Uptake and Umbilical Blood Flow Resulting in Intrauterine Growth Restriction by Tanner, Amelia R, Lynch, Cameron S, Kennedy, Victoria C, Ali, Asghar, Winger, Quinton A, Rozance, Paul J, Anthony, Russell V

“…Deficiency of the placental hormone chorionic somatomammotropin (CSH) can lead to the development of intrauterine growth restriction (IUGR). To gain insight…”
Get full text

Chorionic somatomammotropin RNA interference alters fetal liver glucose utilization by Ali, Asghar, Swanepoel, Callie M, Winger, Quinton A, Rozance, Paul J, Anthony, Russell V

“…Chorionic somatomammotropin (CSH) is a placenta-specific hormone associated with fetal growth, and fetal and maternal metabolism in both humans and sheep. We…”
Get full text

Impact of chorionic somatomammotropin RNA interference on uterine blood flow and placental glucose uptake in the absence of intrauterine growth restriction by Tanner, Amelia R, Lynch, Cameron S, Ali, Asghar, Winger, Quinton A, Rozance, Paul J, Anthony, Russell V

“…Chorionic somatomammotropin (CSH) is one of the most abundantly produced placental hormones, yet its exact function remains elusive. Near-term [135 days of…”
Get more information

Trophectoderm-Specific Knockdown of LIN28 Decreases Expression of Genes Necessary for Cell Proliferation and Reduces Elongation of Sheep Conceptus by Ali, Asghar, Stenglein, Mark D, Spencer, Thomas E, Bouma, Gerrit J, Anthony, Russell V, Winger, Quinton A

“…LIN28 inhibits miRNA maturation which prevents cell differentiation and promotes proliferation. We hypothesized that the LIN28- axis regulates…”
Get full text

Proteomic Characterization of the Nucleolar Linker Histone H1 Interaction Network by Szerlong, Heather J., Herman, Jacob A., Krause, Christine M., DeLuca, Jennifer G., Skoultchi, Arthur, Winger, Quinton A., Prenni, Jessica E., Hansen, Jeffrey C.

“…To investigate the relationship between linker histone H1 and protein–protein interactions in the nucleolus, we used biochemical and proteomics approaches to…”
Get full text

Effects of age on follicular fluid exosomal microRNAs and granulosa cell transforming growth factor-β signalling during follicle development in the mare by da Silveira, Juliano C, Winger, Quinton A, Bouma, Gerrit J, Carnevale, Elaine M

“…Age-related decline in fertility is a consequence of low oocyte number and/or low oocyte competence resulting in pregnancy failure. Transforming growth factor…”
Get more information

Thermoresponsive Self-Immolative Polyglyoxylamides by Rabiee Kenaree, Amir, Sirianni, Quinton E. A, Classen, Kyle, Gillies, Elizabeth R

“…Thermoresponsive polymers with lower critical solution temperatures (LCSTs) are of significant interest for a wide range of applications from sensors to drug…”
Get full text

High-fat diet during pregnancy promotes fetal skeletal muscle fatty acid oxidation and insulin resistance in an ovine model by Omar, Asma K, Li Puma, Lance C, Whitcomb, Luke A, Risk, Briana D, Witt, Aria C, Bruemmer, Jason E, Winger, Quinton A, Bouma, Gerrit J, Chicco, Adam J

“…Maternal diet during pregnancy is associated with offspring metabolic risk trajectory in humans and animal models, but the prenatal origins of these effects…”
Get more information