Search Results - "Quintao, Nara L. M"

Antihyperalgesic Activity of the Methanol Extract and Some Constituents Obtained From Polygala cyparissias (Polygalaceae) by Klein-Júnior, Luiz C., Meira, Nicole A., Bresolin, Tania M. B., Cechinel-Filho, Valdir, Quintão, Nara L. M.

“…Polygala cyparissias, used in folk medicine as an anaesthetic, has already demonstrated antinociceptive activity against acute pain. In this study, we…”
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Cytotoxic, Antitumour and Antimetastatic Activity of Two New Polyacetylenes Isolated from Vernonia scorpioides (Lam.) Pers by Klein, Juliana B., Nowill, Alexandre E., Franchi, Gilberto C., Biavatti, Maique W., Quintão, Nara L.M., Freitas, Rilton A.

“…Vernonia scorpioides (Lam.) Pers., popularly known as Enxuga, Erva‐de‐São Simão and Piracá, has been used in folk medicine for its anti‐inflammatory, wound…”
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N-Antipyrine-3, 4-Dichloromaleimide, an Effective Cyclic Imide for the Treatment of Chronic Pain: The Role of the Glutamatergic System by Quintão, Nara L. M., da Silva, Gislaine F., Antonialli, Carla S., de Campos-Buzzi, Fátima, Corrêa, Rogerio, Filho, Valdir Cechinel

“…In recent years, cyclic imides have attracted the attention of the scientific community because of their promising therapeutic potential. Studies with the…”
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Water soluble microparticles of Sambucus nigra L. (elderberry) as a potential herbal medicine by de Souza, Angelita B, Testoni, Letícia D, Pereira, Thayna B, Quintão, Nara L M, Santin, José R, Bresolin, Tania M B, Couto, Angélica G

“…Although traditional use of elderberry flowers is recognized by Medical Agencies, there are not suitable products on the Brazilian market. To overcome poor…”
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Relevance of tumour necrosis factor‐α for the inflammatory and nociceptive responses evoked by carrageenan in the mouse paw by Rocha, Ana C C, Fernandes, Elizabeth S, Quintão, Nara L M, Campos, Maria M, Calixto, João B

“…1 The present study evaluated the participation of tumour necrosis factor‐α (TNF‐α) in the inflammatory and nociceptive responses evoked by carrageenan in the…”
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Anti-hyperalgesic effects of two sphingosine derivatives in different acute and chronic models of hyperalgesia in mice by Cavichioli, Felipe J, Bernal, Graylin N B, Holzmann, Iandra, Klein, Juliana Bagatini, Escarcena, Ricardo, Del Olmo, Esther, San Feliciano, Arturo, Cechinel Filho, Valdir, Quintão, Nara L M

“…The study evaluated the effects of two sphingosine derivatives N-(2-tert-butoxycarbamylhexadecyl)glutaramide (AA) and N-(1-benzyloxyhexadec-2-yl)glutaramide…”
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Neuropathic Pain-Like Behavior after Brachial Plexus Avulsion in Mice: The Relevance of Kinin B1 and B2 Receptors by Quintao, Nara L. M, Passos, Giselle F, Medeiros, Rodrigo, Paszcuk, Ana F, Motta, Fabiana L, Pesquero, Joao B, Campos, Maria M, Calixto, Joao B

“…The relevance of kinin B(1) (B(1)R) and B(2) (B(2)R) receptors in the brachial plexus avulsion (BPA) model was evaluated in mice, by means of genetic and…”
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Cannabinoid agonists inhibit neuropathic pain induced by brachial plexus avulsion in mice by affecting glial cells and MAP kinases by Paszcuk, Ana F, Dutra, Rafael C, da Silva, Kathryn A B S, Quintão, Nara L M, Campos, Maria M, Calixto, João B

“…Many studies have shown the antinociceptive effects of cannabinoid (CB) agonists in different models of pain. Herein, we have investigated their relevance in…”
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Analysis of the Effect of the TRPC4/TRPC5 Blocker, ML204, in Sucrose-Induced Metabolic Imbalance by Araújo, Mizael C, Soczek, Suzany H. S, Pontes, Jaqueline P, Pinto, Bruno A. S, França, Lucas M, Soley, Bruna da Silva, Santos, Gabriela S, Saminez, Warlison F. de Silva, Fernandes, Fernanda K. M, Lima, João L. do Carmo, Maria-Ferreira, Daniele, Rodrigues, João F. S, Quintão, Nara L. M, Monteiro-Neto, Valério, Paes, Antônio M. A, Fernandes, Elizabeth S

“…Sugar-induced metabolic imbalances are a major health problem since an excessive consumption of saccharides has been linked to greater obesity rates at a…”
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Aleurites moluccana (L.) Willd. Leaves : Mechanical Antinociceptive Properties of a Standardized Dried Extract and Its Chemical Markers by de Souza, Márcia Maria, Cechinel Filho, Valdir, Bresolin, Tania M. B., Quintão, Nara L. M., Malheiros, Angela, Lucinda-Silva, Ruth M., Rocha, Lilian W., Meyre-Silva, Christiane, Silva, Gislaine F., Antonialli, Carla S.

“…Seeking to develop a new analgesic phytomedicine, a spray-dried extract (SDE) of Aleurites moluccana (L.) Willd. leaves was developed in scale up (5 kg). The…”
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Taxane‐induced neurotoxicity: Pathophysiology and therapeutic perspectives by Costa, Robson, Passos, Giselle F., Quintão, Nara L.M., Fernandes, Elizabeth S., Maia, João Raphael L.C.B., Campos, Maria Martha, Calixto, João B.

“…Taxane‐derived drugs are antineoplastic agents used for the treatment of highly common malignancies. Paclitaxel and docetaxel are the most commonly used…”
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Automated preclinical detection of mechanical pain hypersensitivity and analgesia by Zhang, Zihe, Roberson, David P., Kotoda, Masakazu, Boivin, Bruno, Bohnslav, James P., González-Cano, Rafael, Yarmolinsky, David A., Turnes, Bruna Lenfers, Wimalasena, Nivanthika K., Neufeld, Shay Q., Barrett, Lee B., Quintão, Nara L. M., Fattori, Victor, Taub, Daniel G., Wiltschko, Alexander B., Andrews, Nick A., Harvey, Christopher D., Datta, Sandeep Robert, Woolf, Clifford J.

“…The lack of sensitive and robust behavioral assessments of pain in preclinical models has been a major limitation for both pain research and the development of…”
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Synthetic chalcones as potential tool for acute- and chronic-pain control by Rocha, Lilian W., Sonza, Daniele R., Broering, Milena Fronza, Nunes, Roberta, de Campos-Buzzi, Fátima, Corrêa, Rogério, Silva, Rangel L., Cunha, Thiago M., Santin, José Roberto, Quintão, Nara L.M.

“…[Display omitted] •Chalcones presented anti-hypersesitivity and anti-inflammatory effects.•The bioavailability of the comound was shown presented in vivo and…”
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The kinin B 1 and B 2 receptors and TNFR1/p55 axis on neuropathic pain in the mouse brachial plexus by Quintão, Nara L M, Rocha, Lilian W, da Silva, Gislaine F, Paszcuk, Ana F, Manjavachi, Marianne N, Bento, Allisson F, da Silva, Kathryn Ana B S, Campos, Maria M, Calixto, João B

“…Tumour necrosis factor (TNF) and kinins have been associated with neuropathic pain-like behaviour in numerous animal models. However, the way that they…”
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Neuropathic Pain-Like Behavior after Brachial Plexus Avulsion in Mice: The Relevance of Kinin B 1 and B 2 Receptors by Quintão, Nara L. M., Passos, Giselle F., Medeiros, Rodrigo, Paszcuk, Ana F., Motta, Fabiana L., Pesquero, João B., Campos, Maria M., Calixto, João B.

“…The relevance of kinin B 1 (B 1 R) and B 2 (B 2 R) receptors in the brachial plexus avulsion (BPA) model was evaluated in mice, by means of genetic and…”
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Anti-inflammatory and antinociceptive effects of Baccharis dracunculifolia DC (Asteraceae) in different experimental models by dos Santos, Diogo A., Fukui, Murilo de J., Dhammika Nanayakkara, N.P., Khan, Shabana I., Sousa, João Paulo B., Bastos, Jairo K., Andrade, Sérgio F., da Silva Filho, Ademar A., Quintão, Nara L.M.

“…This study demonstrated that Baccharis dracunculifolia extract (BdE), a native plant to southern Brazil and the major source of green propolis, had…”
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Chemical composition and evaluation of the anti-hypernociceptive effect of the essential oil extracted from the leaves of Ugni myricoides on inflammatory and neuropathic models of pain in mice by Quintão, Nara L, da Silva, Gislaine F, Antonialli, Carla S, Rocha, Lilian W, Cechinel Filho, Valdir, Cicció, José F

“…The study analyzes the chemical composition of the essential oil obtained from the leaves of Ugni myricoides (Kunth) O. Berg (U. myricoides EO). The…”
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The Effects of Diacerhein on Mechanical Allodynia in Inflammatory and Neuropathic Models of Nociception in Mice by Quintão, Nara L. M., Medeiros, Rodrigo, Santos, Adair R.S., Campos, Maria M., Calixto, João B.

“…In this study we analyzed the systemic antiallodynic properties of diacerhein, a drug used to treat osteoarthritis, in inflammatory and neuropathic models of…”
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Biological and Toxicological Evaluation of N-(4methyl-phenyl)-4-methylphthalimide on Bone Cancer in Mice by Santin, José R, da Silva, Gislaine F, Pastor, Maria V D, Broering, Milena F, Nunes, Roberta, Braga, Rodolpho C, de Sousa, Iury T S, Stiz, Dorimar S, da Silva, Kathryn A B S, Stoeberl, Luis C, Corrêa, Rogério, Filho, Valdir C, Dos Santos, Carlos E M, Quintão, Nara L M

“…It was recently demonstrated that the phthalimide N-(4-methyl-phenyl)-4- methylphthalimide (MPMPH-1) has important effects against acute and chronic pain in…”
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Mechanisms underlying the nociceptive and inflammatory responses induced by trypsin in the mouse paw by Paszcuk, Ana Flávia, Quintão, Nara L.M., Fernandes, Elizabeth S., Juliano, Luiz, Chapman, Kevin, Andrade-Gordon, Patricia, Campos, Maria Martha, Vergnolle, Nathalie, Calixto, João B.

“…It has been demonstrated that trypsin is able to evoke the classical signals of inflammation, mainly via the activation of proteinase-activated receptor-2…”
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