Search Results - "Quintanova, Catarina"

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    Design, synthesis and neuroprotective evaluation of novel tacrine–benzothiazole hybrids as multi-targeted compounds against Alzheimer’s disease by Keri, Rangappa S., Quintanova, Catarina, Marques, Sérgio M., Esteves, A. Raquel, Cardoso, Sandra M., Santos, M. Amélia

    Published in Bioorganic & medicinal chemistry (01-08-2013)
    “…Hybrid compounds based on a suitable conjugation of tacrine and benzothiazole (BTA) moieties were designed and prepared. Their activity as inhibitors of AChE…”
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    Journal Article
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    Phosphorylated claudin-16 interacts with Trpv5 and regulates transcellular calcium transport in the kidney by Hou, Jianghui, Renigunta, Vijay, Nie, Mingzhu, Sunq, Abby, Himmerkus, Nina, Quintanova, Catarina, Bleich, Markus, Renigunta, Aparna, Wolf, Matthias Tilmann Florian

    “…Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC)was previously considered to be a paracellular channelopathy caused by mutations in the…”
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    Journal Article
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    Unrecognized role of claudin‐10b in basolateral membrane infoldings of the thick ascending limb by Quintanova, Catarina, Himmerkus, Nina, Svendsen, Samuel L., Schwerdtner, Otto, Merkel, Cosima, Pinckert, Lennart, Mutig, Kerim, Breiderhoff, Tilman, Müller, Dominik, Günzel, Dorothee, Bleich, Markus

    Published in Annals of the New York Academy of Sciences (01-11-2022)
    “…Claudin‐10b is an important component of the tight junction in the thick ascending limb (TAL) of Henle's loop and allows paracellular sodium transport. In…”
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    Journal Article
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    New Tacrine Hybrids with Natural-Based Cysteine Derivatives as Multitargeted Drugs for Potential Treatment of Alzheimer's Disease by Keri, Rangappa S., Quintanova, Catarina, Chaves, Sílvia, Silva, Diana F., Cardoso, Sandra M., Santos, M. Amélia

    Published in Chemical biology & drug design (01-01-2016)
    “…Alzheimer's disease (AD) is a devastating age‐dependent neurodegenerative disorder. The main hallmarks are impairment of cholinergic system and accumulation in…”
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    Journal Article
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    Multifunctional iron-chelators with protective roles against neurodegenerative diseases by Nunes, Andreia, Marques, Sérgio M, Quintanova, Catarina, Silva, Diana F, Cardoso, Sandra M, Chaves, Sílvia, Santos, M Amélia

    “…The multifactorial nature of Alzheimer's disease (AD), and the absence of a disease modifying drug, makes the development of new multifunctional drugs an…”
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    Journal Article
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    Copper(II) complexation of tacrine hybrids with potential anti-neurodegenerative roles by Quintanova, Catarina, Keri, Rangappa S., Chaves, Sílvia, Santos, M. Amélia

    Published in Journal of inorganic biochemistry (01-10-2015)
    “…The complexity and multifactorial nature of neurodegenerative diseases turn quite difficult the development of adequate drugs for their treatment. Multi-target…”
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    Journal Article
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    Design, synthesis and neuroprotective evaluation of novel tacrineabenzothiazole hybrids as multi-targeted compounds against Alzheimeras disease by Keri, Rangappa, Quintanova, Catarina, Marques, Sergio, Esteves, A, Cardoso, Sandra, Santos, M

    Published in Bioorganic & medicinal chemistry (01-08-2013)
    “…Alzheimeras disease (AD) is a multifactorial disorder with several target proteins contributing to its etiology. In search for multifunctional anti-AD drug…”
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    Journal Article
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    Viewing Cortical Collecting Duct Function Through Phenotype-guided Single-Tubule Proteomics by Himmerkus, Nina, Svendsen, Samuel L, Quintanova, Catarina, Bleich, Markus, Von Schwerdtner, Otto, Benzing, Thomas, Welling, Paul A, Leipziger, Jens, Rinschen, Markus M

    Published in Function (Oxford, England) (01-01-2020)
    “…The revolution of the omics technologies has enabled profiling of the molecules of any sample. However, the heterogeneity of the kidney with highly specialized…”
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    Journal Article
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    Novos Compostos híbridos Com Potencial ação Neuroprotetora by Quintanova, Catarina Isabel Rina

    Published 01-01-2013
    “…A doença de Alzheimer (AD) é uma doença neurodegenerativa progressiva e é considerada a forma mais comum de demência na população idosa. Atualmente, apesar dos…”
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    Dissertation