Search Results - "Quinn, Niall"
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1
New estimates of flood exposure in developing countries using high-resolution population data
Published in Nature communications (18-04-2019)“…Current estimates of global flood exposure are made using datasets that distribute population counts homogenously across large lowland floodplain areas. When…”
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2
The Movement Disorder Society Criteria for the Diagnosis of Multiple System Atrophy
Published in Movement disorders (01-06-2022)“…ABSTRACT Background The second consensus criteria for the diagnosis of multiple system atrophy (MSA) are widely recognized as the reference standard for…”
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3
What do patients with scans without evidence of dopaminergic deficit (SWEDD) have? New evidence and continuing controversies
Published in Journal of Neurology, Neurosurgery and Psychiatry (01-03-2016)“…The term SWEDD (scans without evidence for dopaminergic deficit) refers to the absence, rather than the presence, of an imaging abnormality in patients…”
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4
Inequitable patterns of US flood risk in the Anthropocene
Published in Nature climate change (01-02-2022)“…Current flood risk mapping, relying on historical observations, fails to account for increasing threat under climate change. Incorporating recent developments…”
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"Atypical" atypical parkinsonism: New genetic conditions presenting with features of progressive supranuclear palsy, corticobasal degeneration, or multiple system atrophy-A diagnostic guide
Published in Movement disorders (01-08-2013)“…ABSTRACT Recently, a number of genetic parkinsonian conditions have been recognized that share some features with the clinical syndromes of progressive…”
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6
Improving diagnostic accuracy of multiple system atrophy: a clinicopathological study
Published in Brain (London, England : 1878) (01-09-2019)“…Clinical diagnosis of multiple system atrophy is challenging and many patients with Lewy body disease (i.e. Parkinson's disease or dementia with Lewy bodies)…”
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7
The Spatial Dependence of Flood Hazard and Risk in the United States
Published in Water resources research (01-03-2019)“…In this paper we seek to understand the nature of flood spatial dependence over the conterminous United States. We extend an existing conditional multivariate…”
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8
Quality of life in Parkinson's disease: The relative importance of the symptoms
Published in Movement disorders (30-07-2008)“…A body of literature now exists, which demonstrates that idiopathic Parkinson's disease (PD) has a major negative impact on quality of life (QoL), and that…”
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Combined Modeling of US Fluvial, Pluvial, and Coastal Flood Hazard Under Current and Future Climates
Published in Water resources research (01-02-2021)“…This study reports a new and significantly enhanced analysis of US flood hazard at 30 m spatial resolution. Specific improvements include updated hydrography…”
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10
Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants
Published in Science translational medicine (30-06-2010)“…Troublesome involuntary movements in the absence of dopaminergic medication, so-called off-medication dyskinesias, are a serious adverse effect of fetal neural…”
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Deep brain stimulation plus best medical therapy versus best medical therapy alone for advanced Parkinson's disease (PD SURG trial): a randomised, open-label trial
Published in Lancet neurology (01-06-2010)“…Summary Background Surgical intervention for advanced Parkinson's disease is an option if medical therapy fails to control symptoms adequately. We aimed to…”
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Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
Published in Nature medicine (01-05-2008)“…Two subjects with Parkinson's disease who had long-term survival of transplanted fetal mesencephalic dopaminergic neurons (11-16 years) developed…”
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Graft-induced dyskinesias in Parkinson's disease: High striatal serotonin/dopamine transporter ratio
Published in Movement disorders (01-09-2011)“…Graft‐induced dyskinesias are a serious complication after neural transplantation in Parkinson's disease. One patient with Parkinson's disease, treated with…”
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14
Tremor-some controversial aspects
Published in Movement disorders (01-01-2011)“…The commonest cause of pathological tremor is essential tremor (ET). However, it has proved difficult to identify genetic mutations causing ET, particularly…”
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Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions
Published in eLife (28-05-2020)“…Genetic interactions, including synthetic lethal effects, can now be systematically identified in cancer cell lines using high-throughput genetic perturbation…”
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16
Soft signs in movement disorders: friends or foes?
Published in Journal of neurology, neurosurgery and psychiatry (01-08-2019)Get full text
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17
Population exposure to flooding in Small Island Developing States under climate change
Published in Environmental research letters (01-12-2024)“…Abstract Estimates of current and future population exposure to both coastal and inland flooding do not exist consistently in all Small Island Developing…”
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Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner
Published in Cell death & disease (08-08-2022)“…Metastatic malignant melanoma is the deadliest skin cancer, and it is characterised by its high resistance to apoptosis. The main melanoma driving mutations…”
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Deep brain stimulation effects in dystonia: Time course of electrophysiological changes in early treatment
Published in Movement disorders (15-08-2011)“…Deep brain stimulation to the internal globus pallidus is an effective treatment for primary dystonia. The optimal clinical effect often occurs only weeks to…”
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A climate-conditioned catastrophe risk model for UK flooding
Published in Natural hazards and earth system sciences (07-03-2023)“…We present a transparent and validated climate-conditioned catastrophe flood model for the UK, that simulates pluvial, fluvial and coastal flood risks at 1…”
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