Search Results - "Quinn, Mark T"

Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymes by Kawahara, Tsukasa, Quinn, Mark T, Lambeth, J David

“…NADPH-oxidases (Nox) and the related Dual oxidases (Duox) play varied biological and pathological roles via regulated generation of reactive oxygen species…”
Get full text

Neutrophil Immunomodulatory Activity of Natural Organosulfur Compounds by Schepetkin, Igor A, Kirpotina, Liliya N, Khlebnikov, Andrei I, Balasubramanian, Narayanaganesh, Quinn, Mark T

“…Organosulfur compounds are bioactive components of garlic essential oil (EO), mustard oil, EOs, asafoetida, and other plant and food extracts. Traditionally,…”
Get full text

Anti-Inflammatory Activity of Pyrazolo[1,5- a ]quinazolines by Crocetti, Letizia, Khlebnikov, Andrei I, Guerrini, Gabriella, Schepetkin, Igor A, Melani, Fabrizio, Giovannoni, Maria Paola, Quinn, Mark T

“…Chronic inflammation contributes to a number of diseases. Therefore, control of the inflammatory response is an important therapeutic goal. To identify novel…”
Get full text

Innate Immunomodulatory Activity of Cedrol, a Component of Essential Oils Isolated from Juniperus Species by Özek, Gulmira, Schepetkin, Igor A, Yermagambetova, Moldir, Özek, Temel, Kirpotina, Liliya N, Almerekova, Shyryn S, Abugalieva, Saule I, Khlebnikov, Andrei I, Quinn, Mark T

“…Little is known about the immunomodulatory activity of essential oils isolated from species. Thus, we isolated essential oils from the cones and leaves of…”
Get full text

Essential Oils from Monarda fistulosa : Chemical Composition and Activation of Transient Receptor Potential A1 (TRPA1) Channels by Ghosh, Monica, Schepetkin, Igor A, Özek, Gulmira, Özek, Temel, Khlebnikov, Andrei I, Damron, Derek S, Quinn, Mark T

“…Little is known about the pharmacological activity of L. essential oils. To address this issue, we isolated essential oils from the flowers and leaves of and…”
Get full text

Chemical Composition and Immunomodulatory Activity of Essential Oils from Rhododendron albiflorum by Schepetkin, Igor A., Özek, Gulmira, Özek, Temel, Kirpotina, Liliya N., Khlebnikov, Andrei I., Quinn, Mark T.

“…Rhododendron (Ericaceae) extracts contain flavonoids, chromones, terpenoids, steroids, and essential oils and are used in traditional ethnobotanical medicine…”
Get full text

Physicochemical Characterization and Antioxidant Activity of Humic Acids Isolated from Peat of Various Origins by Zykova, Maria V, Schepetkin, Igor A, Belousov, Michael V, Krivoshchekov, Sergey V, Logvinova, Lyudmila A, Bratishko, Kristina A, Yusubov, Mekhman S, Romanenko, Sergey V, Quinn, Mark T

“…Although humic acids (HAs) from peat exhibit various therapeutic properties, there is little information available concerning their physicochemical and…”
Get full text

Oximes: Novel Therapeutics with Anticancer and Anti-Inflammatory Potential by Schepetkin, Igor A., Plotnikov, Mark B., Khlebnikov, Andrei I., Plotnikova, Tatiana M., Quinn, Mark T.

“…Oximes have been studied for decades because of their significant roles as acetylcholinesterase reactivators. Over the last twenty years, a large number of…”
Get full text

Volatile Composition, Antimicrobial Activity, and In Vitro Innate Immunomodulatory Activity of Echinacea purpurea (L.) Moench Essential Oils by Dosoky, Noura S, Kirpotina, Liliya N, Schepetkin, Igor A, Khlebnikov, Andrei I, Lisonbee, Brent L, Black, Jeffrey L, Woolf, Hillary, Thurgood, Trever L, Graf, Brittany L, Satyal, Prabodh, Quinn, Mark T

“…(L.) Moench is a medicinal plant commonly used for the treatment of upper respiratory tract infections, the common cold, sore throat, migraine, colic, stomach…”
Get full text

Chemical Composition and Antibacterial Activity of Essential Oils from Ferula L. Species against Methicillin-Resistant Staphylococcus aureus by Utegenova, Gulzhakhan A, Pallister, Kyler B, Kushnarenko, Svetlana V, Özek, Gulmira, Özek, Temel, Abidkulova, Karime T, Kirpotina, Liliya N, Schepetkin, Igor A, Quinn, Mark T, Voyich, Jovanka M

“…Essential oils (EOs) were obtained by hydrodistillation of various parts of (Boiss.) Boiss., Krasn. ex. Korovin, and B. Fedtsch. ex Koso-Pol., collected in the…”
Get full text

Neutrophil Immunomodulatory Activity of (−)-Borneol, a Major Component of Essential Oils Extracted from Grindelia squarrosa by Schepetkin, Igor A., Özek, Gulmira, Özek, Temel, Kirpotina, Liliya N., Khlebnikov, Andrei I., Quinn, Mark T.

“…Grindelia squarrosa (Pursh) Dunal is used in traditional medicine for treating various diseases; however, little is known about the immunomodulatory activity…”
Get full text

Structure and regulation of the neutrophil respiratory burst oxidase: comparison with nonphagocyte oxidases by Quinn, Mark T., Gauss, Katherine A.

“…Neutrophils play an essential role in the body’s innate defense against pathogens and are one of the primary mediators of the inflammatory response. To defend…”
Get full text

Pyridazinones and Structurally Related Derivatives with Anti-Inflammatory Activity by Cantini, Niccolo, Schepetkin, Igor A., Danilenko, Nadezhda V., Khlebnikov, Andrei I., Crocetti, Letizia, Giovannoni, Maria Paola, Kirpotina, Liliya N., Quinn, Mark T.

“…Persistent inflammation contributes to a number of diseases; therefore, control of the inflammatory response is an important therapeutic goal. In an effort to…”
Get full text

Novel Tryptanthrin Derivatives with Selectivity as c -Jun N-Terminal Kinase (JNK) 3 Inhibitors by Schepetkin, Igor A, Karpenko, Oleksander S, Kovrizhina, Anastasia R, Kirpotina, Liliya N, Khlebnikov, Andrei I, Chekal, Stepan I, Radudik, Alevtyna V, Shybinska, Maryna O, Quinn, Mark T

“…The -Jun N-terminal kinase (JNK) family includes three proteins (JNK1-3) that regulate many physiological processes, including cell proliferation and…”
Get full text

Bidirectional interactions between NOX2‐type NADPH oxidase and the F‐actin cytoskeleton in neuronal growth cones by Munnamalai, Vidhya, Weaver, Cory J., Weisheit, Corinne E., Venkatraman, Prahatha, Agim, Zeynep Sena, Quinn, Mark T., Suter, Daniel M.

“…NADPH oxidases are important for neuronal function but detailed subcellular localization studies have not been performed. Here, we provide the first evidence…”
Get full text

1H-pyrrolo[2,3-b]pyridine: A new scaffold for human neutrophil elastase (HNE) inhibitors by Crocetti, Letizia, Giovannoni, Maria Paola, Schepetkin, Igor A., Quinn, Mark T., Khlebnikov, Andrei I., Cantini, Niccolò, Guerrini, Gabriella, Iacovone, Antonella, Teodori, Elisabetta, Vergelli, Claudia

“…[Display omitted] Human neutrophil elastase (HNE) is a potent serine protease belonging to the chymotrypsin family. It is an important target for the…”
Get full text

Chemical Composition and Immunomodulatory Activity of Hypericum perforatum Essential Oils by Schepetkin, Igor A, Özek, Gulmira, Özek, Temel, Kirpotina, Liliya N, Khlebnikov, Andrei I, Quinn, Mark T

“…L. (Hypericaceae) extracts have been used for their therapeutic effects; however, not much is known about the immunomodulatory activity of essential oils…”
Get full text

Immunomodulatory Activity of Polysaccharides Isolated from Saussurea salicifolia L. and Saussurea frolovii Ledeb by Schepetkin, Igor A, Danilets, Marina G, Ligacheva, Anastasia A, Trofimova, Evgenia S, Selivanova, Natalia S, Sherstoboev, Evgenii Yu, Krivoshchekov, Sergei V, Gulina, Ekaterina I, Brazovskii, Konstantin S, Kirpotina, Liliya N, Quinn, Mark T, Belousov, Mikhail V

“…The genus has been used in the preparation of therapies for a number of medical problems, yet not much is known about the therapeutic high-molecular-weight…”
Get full text

Inhibition of Acetylcholinesterase by Novel Lupinine Derivatives by Schepetkin, Igor A, Nurmaganbetov, Zhangeldy S, Fazylov, Serik D, Nurkenov, Oralgazy A, Khlebnikov, Andrei I, Seilkhanov, Tulegen M, Kishkentaeva, Anarkul S, Shults, Elvira E, Quinn, Mark T

“…Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive memory loss and cognitive impairment due in part to a severe loss of…”
Get full text

Therapeutic Effects of Tryptanthrin and Tryptanthrin-6-Oxime in Models of Rheumatoid Arthritis by Kirpotina, Liliya N., Schepetkin, Igor A., Hammaker, Deepa, Kuhs, Amanda, Khlebnikov, Andrei I., Quinn, Mark T.

“…Rheumatoid arthritis (RA) is a chronic autoimmune disease involving joint and bone damage that is mediated in part by proteases and cytokines produced by…”
Get full text