Search Results - "Quinn, E J"

The role of BRCA1 in transcriptional regulation and cell cycle control by Mullan, P B, Quinn, J E, Harkin, D P

“…The exact functions of BRCA1 have not been fully described but it now seems apparent that it has roles in DNA damage repair, transcriptional regulation, cell…”
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The Role of BRCA1 in the Cellular Response to Chemotherapy by Kennedy, Richard D., Quinn, Jennifer E., Mullan, Paul B., Johnston, Patrick G., Harkin, D. Paul

“…Germline mutations of the BRCA1 gene account for approximately 5% of breast and ovarian cancer cases, and lower than normal BRCA1 expression or function may be…”
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The effect of osteoprotegerin administration on the intra-tibial growth of the osteoblastic LuCaP 23.1 prostate cancer xenograft by Kiefer, J A, Vessella, R L, Quinn, J E, Odman, A M, Zhang, J, Keller, E T, Kostenuik, P J, Dunstan, C R, Corey, E

“…Osteoprotegerin (OPG) plays a central role in controlling bone resorption. Exogenous administration of OPG has been shown to be effective in preventing…”
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Comparison of Fc-osteoprotegerin and zoledronic acid activities suggests that zoledronic acid inhibits prostate cancer in bone by indirect mechanisms by Quinn, J E, Brown, L G, Zhang, J, Keller, E T, Vessella, R L, Corey, E

“…Zoledronic acid (ZA) has been shown to inhibit prostate tumor growth in vitro and have beneficial effects in patients with advanced prostate cancer (CaP). The…”
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Role played by BRCA1 in regulating the cellular response to stress by Gilmore, P M, Quinn, J E, Mullan, P B, Andrews, H N, McCabe, N, Carty, M, Kennedy, R D, Harkin, D P

“…BRCA1 (breast-cancer susceptibility gene 1) is a tumour suppressor gene that is mutated in the germline of women with a genetic predisposition to breast and…”
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Effects of phenylbutyrate on proliferation and apoptosis in human prostate cancer cells in vitro and in vivo by Melchior, S W, Brown, L G, Figg, W D, Quinn, J E, Santucci, R A, Brunner, J, Thüroff, J W, Lange, P H, Vessella, R L

“…Phenylbutyrate (PB) is a potent differentiating agent and currently under investigation for the treatment of prostate cancer (CaP) and other malignancies. We…”
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BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubule agents by MULLAN, Paul B, QUINN, Jennifer E, MAHESWARAN, Shyamala, LIU, Edison, HABER, Daniel A, JOHNSTON, Patrick G, HARKIN, D. Paul, GILMORE, Paula M, MCWILLIAMS, Stewart, ANDREWS, Heather, GERVIN, Celine, MCCABE, Nuala, MCKENNA, Sarah, WHITE, Pat, SONG, Young-Han

“…BRCA1 is a tumour suppressor gene implicated in the predisposition to early onset breast and ovarian cancer. We have generated cell lines with inducible…”
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Cooperative effects in simulated water by Barnes, P, Finney, J. L, Nicholas, J. D, Quinn, J. E

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The CWH8 Gene Encodes a Dolichyl Pyrophosphate Phosphatase with a Luminally Oriented Active Site in the Endoplasmic Reticulum of Saccharomyces cerevisiae by Fernandez, Fabiana, Rush, Jeffrey S., Toke, David A., Han, Gil-soo, Quinn, Jeanette E., Carman, George M., Choi, Jae-Yeon, Voelker, Dennis R., Aebi, Markus, Waechter, Charles J.

“…Mutations in theCWH8 gene, which encodes an ER transmembrane protein with a phosphate binding pocket in Saccharomyces cerevisiae, result in a deficiency in…”
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Molecular Basis for Estrogen Receptor   Deficiency in BRCA1-Linked Breast Cancer by Hosey, A. M., Gorski, J. J., Murray, M. M., Quinn, J. E., Chung, W. Y., Stewart, G. E., James, C. R., Farragher, S. M., Mulligan, J. M., Scott, A. N., Dervan, P. A., Johnston, P. G., Couch, F. J., Daly, P. A., Kay, E., McCann, A., Mullan, P. B., Harkin, D. P.

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The quest for regolithic howardites. Part 1: Two trends uncovered using noble gases by Cartwright, J.A., Ott, U., Mittlefehldt, D.W., Herrin, J.S., Herrmann, S., Mertzman, S.A., Mertzman, K.R., Peng, Z.X., Quinn, J.E.

“…We report noble gas data (helium (He), neon (Ne), argon (Ar), krypton (Kr) and xenon (Xe)), nominal gas retention ages (K–Ar, U–Th–He) and cosmic ray exposure…”
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BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers by Buckley, Niamh E, Nic An tSaoir, Caoimhe B, Blayney, Jaine K, Oram, Lisa C, Crawford, Nyree T, D'Costa, Zenobia C, Quinn, Jennifer E, Kennedy, Richard D, Harkin, D Paul, Mullan, Paul B

“…Here, we show for the first time, that the familial breast/ovarian cancer susceptibility gene BRCA1 activates the Notch pathway in breast cells by…”
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Some caveats on ... dental practice sale advisors by Quinn, J E

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Trends in dental computerization in Oklahoma practices by Quinn, J E

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Abstract B051: The identification of the Thromboxane A2 receptor as an oncogenic driver in triple-negative breast cancer by Orr, K S., Buckley, N E., Quinn, J E., James, C R., Blainey, J., Mullan, P. B.

“…Abstract Purpose of Study: To identify and characterise genes involved in driving the oncogenesis of Triple Negative Breast Cancer (TNBC), and assess the…”
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The effect of jejunoileal bypass on the pharmacokinetics of digoxin in man by Marcus, F I, Quinn, E J, Horton, H, Jacobs, S, Pippin, S, Stafford, M, Zukoski, C

“…Seven subjects who underwent jejunoileal bypass surgery for massive obesity participated in a study to examine the relative bioavailability of digoxin before…”
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Business planning for all seasons by Quinn, J E

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BRCA1 expression and efficacy of vinorelbine in malignant mesothelioma by Busacca, S., Gray, S. G., Paul, I., McTavish, N., O'Byrne, K. J., Quinn, J. E., Fennell, D. A.

“…Abstract only…”
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Surviving hard times in your practice by Quinn, J E

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Delegate key functions to your staff for productivity by Quinn, J E

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