Search Results - "Quinn, Charles T"

l-Glutamine for sickle cell anemia: more questions than answers by Quinn, Charles T.

“…In 2017, the Food and Drug Administration approved 2 medications for sickle cell anemia (SCA): hydroxyurea for children and l-glutamine for children and…”
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Association between diffuse myocardial fibrosis and diastolic dysfunction in sickle cell anemia by Niss, Omar, Fleck, Robert, Makue, Fowe, Alsaied, Tarek, Desai, Payal, Towbin, Jeffrey A., Malik, Punam, Taylor, Michael D., Quinn, Charles T.

“…Sickle cell anemia (SCA)–related cardiomyopathy is characterized by diastolic dysfunction and hyperdynamic features. Diastolic dysfunction portends early…”
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Cardiomyopathy With Restrictive Physiology in Sickle Cell Disease by Niss, Omar, MD, Quinn, Charles T., MD, MS, Lane, Adam, PhD, Daily, Joshua, MD, Khoury, Philip R., MS, Bakeer, Nihal, MD, Kimball, Thomas R., MD, Towbin, Jeffrey A., MD, Malik, Punam, MD, Taylor, Michael D., MD, PhD

“…Abstract Objectives The aim of this study was to identify a unifying cardiac pathophysiology that explains the cardiac pathological features in sickle cell…”
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Automated Oxygen Gradient Ektacytometry: A Novel Biomarker in Sickle Cell Anemia by Sadaf, Alina, Seu, Katie G, Thaman, Elizabeth, Fessler, Rose, Konstantinidis, Diamantis G, Bonar, Holly A, Korpik, Jennifer, Ware, Russell E, McGann, Patrick T, Quinn, Charles T, Kalfa, Theodosia A

“…Sickle cell anemia (SCA) is a hereditary hemoglobinopathy with a variable phenotype. There is no single biomarker that adequately predicts disease severity and…”
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Minireview: Clinical severity in sickle cell disease: the challenges of definition and prognostication by Quinn, Charles T

“…Sickle cell disease (SCD) is a monogenic, yet highly phenotypically variable disease with multisystem pathology. This manuscript provides an overview of many…”
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Hydroxyurea: how much is enough? by Quinn, Charles T.

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Do Red Blood Cell Indices Explain Racial Differences in the Relationship between Hemoglobin A1c and Blood Glucose? by Cohen, Robert M., MD, Smith, Eric P., MD, Arbabi, Shahriar, MD, Quinn, Charles T., MD, MS, Franco, Robert S., PhD

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Increase in Invasive Streptococcus Pneumoniae Infections in Children with Sickle Cell Disease since Pneumococcal Conjugate Vaccine Licensure by McCavit, Timothy L., MD, Quinn, Charles T., MD, MS, Techasaensiri, Chonnamet, MD, Rogers, Zora R., MD

“…Invasive pneumococcal disease (IPD) in children with sickle cell disease has decreased with prophylactic penicillin, pneumococcal polysaccharide vaccine, and…”
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Clinical Utility of the Addition of Molecular Genetic Testing to Newborn Screening for Sickle Cell Anemia by Shook, Lisa M., Haygood, Deidra, Quinn, Charles T.

“…Sickle cell disease (SCD) is a group of related yet genetically complex hemoglobinopathies. Universal newborn screening (NBS) for SCD is performed in the…”
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Implementation of a Process for Initial Transcranial Doppler Ultrasonography in Children With Sickle Cell Anemia by Crosby, Lori E., PsyD, Joffe, Naomi E., PhD, Davis, Blair, MS, Quinn, Charles T., MD, MS, Shook, Lisa, MA, Morgan, Darice, MSN, Simmons, Kenya, MBA, Kalinyak, Karen A., MD

“…Stroke, a devastating complication of sickle cell anemia (SCA), can cause irreversible brain injury with physical and cognitive deficits. Transcranial Doppler…”
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Retrospective comparison of gradient recalled echo R2 and spin-echo R2 magnetic resonance analysis methods for estimating liver iron content in children and adolescents by Serai, Suraj D., Fleck, Robert J., Quinn, Charles T., Zhang, Bin, Podberesky, Daniel J.

“…Background Serial surveillance of liver iron concentration (LIC) provides guidance for chelation therapy in patients with iron overload. The diagnosis of iron…”
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Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment by McInnis, Christine, Bhatia, Shilpa, Vijaykumar, Brinda, Tian, Qiaomu, Sun, Yanbo, Leistritz-Edwards, Del, Quinn, Charles T, Uppaluri, Ravi, Egloff, Ann Marie, Srinivasan, Lakshmi, Pregibon, Daniel C, Coyle, Anthony J, Hanna, Glenn J

“…BackgroundHigh-risk human papillomavirus (HPV) is a primary cause of an increasing number of oropharyngeal squamous cell carcinomas (OPSCCs). The viral…”
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Hydroxyurea Optimization through Precision Study (HOPS): study protocol for a randomized, multicenter trial in children with sickle cell anemia by Meier, Emily R, Creary, Susan E, Heeney, Matthew M, Dong, Min, Appiah-Kubi, Abena O, Nelson, Stephen C, Niss, Omar, Piccone, Connie, Quarmyne, Maa-Ohui, Quinn, Charles T, Saving, Kay L, Scott, John P, Talati, Ravi, Latham, Teresa S, Pfeiffer, Amanda, Shook, Lisa M, Vinks, Alexander A, Lane, Adam, McGann, Patrick T

“…Abstract Background Sickle cell disease (SCD) is a severe and devastating hematological disorder that affects over 100,000 persons in the USA and millions…”
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L-glutamine for sickle cell disease: Knight or pawn? by Sadaf, Alina, Quinn, Charles T

“…Oxidative stress is an important contributor to the pathophysiology of sickle cell disease. The pathways involved are complex and interlinked. L-glutamine is…”
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Iron-Refractory Microcytic Anemia as the Presenting Feature of Unicentric Castleman Disease in Children by Chandrakasan, Shanmuganathan, MD, Bakeer, Nihal, MD, Mo, Jun Qin, MD, Cost, Carrye, MD, Quinn, Charles T., MD, MS

“…Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge. We report the cases of 2 children with occult, unicentric Castleman…”
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Headache and Migraine in Children with Sickle Cell Disease Are Associated with Lower Hemoglobin and Higher Pain Event Rates But Not Silent Cerebral Infarction by Dowling, Michael M., MD, PhD, MSCS, Noetzel, Michael J., MD, Rodeghier, Mark J., PhD, Quinn, Charles T., MD, MS, Hirtz, Deborah G., MD, Ichord, Rebecca N., MD, Kwiatkowski, Janet L., MD, MSCE, Roach, E. Steven, MD, Kirkham, Fenella J., MD, FRCPCH, Casella, James F., MD, DeBaun, Michael R., MD, MPH

“…Objective To identify risk factors for headache and migraine in children with sickle cell disease and test the hypothesis that either or both are independently…”
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Inadequate Dietary Intake in Patients with Thalassemia by Fung, Ellen B., PhD, RD, Xu, Yan, MS, Trachtenberg, Felicia, PhD, Odame, Isaac, MD, Kwiatkowski, Janet L., MD, MSCE, Neufeld, Ellis J., MD, PhD, Thompson, Alexis A., MD, Boudreaux, Jeanne, MD, Quinn, Charles T., MD, MS, Vichinsky, Elliott P., MD

“…Abstract Background Patients with thalassemia have low circulating levels of many nutrients, but the contribution of dietary intake has not been assessed…”
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Clinical Utility of Confirmatory Genetic Testing to Differentiate Sickle Cell Trait from Sickle-β + -Thalassemia by Newborn Screening by Shook, Lisa M, Haygood, Deidra, Quinn, Charles T

“…Hemoglobin separation techniques are the most commonly used laboratory methods in newborn screening and confirmatory testing programs for hemoglobinopathies…”
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Sickle cell disease in childhood: from newborn screening through transition to adult medical care by Quinn, Charles T

“…Sickle cell disease (SCD) is the name for a group of related blood disorders caused by an abnormal hemoglobin molecule that polymerizes on deoxygenation. SCD…”
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Silent cerebral infarction: supply and demand by Quinn, Charles T.

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