Search Results - "Quinn, Ada"

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  1. 1

    The efficacy of the analgesic GlyT2 inhibitor, ORG25543, is determined by two connected allosteric sites by Chater, Ryan Cantwell, Quinn, Ada S, Wilson, Katie, Frangos, Zachary J, Sutton, Patrick, Jayakumar, Srinivasan, Cioffi, Christopher L, O'Mara, Megan L, Vandenberg, Robert J

    Published in Journal of neurochemistry (01-09-2024)
    “…Glycine Transporter 2 (GlyT2) inhibitors have shown considerable potential as analgesics for the treatment of neuropathic pain but also display considerable…”
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    Journal Article
  2. 2

    Structural basis of promiscuous substrate transport by Organic Cation Transporter 1 by Zeng, Yi C., Sobti, Meghna, Quinn, Ada, Smith, Nicola J., Brown, Simon H. J., Vandenberg, Jamie I., Ryan, Renae M., O’Mara, Megan L., Stewart, Alastair G.

    Published in Nature communications (11-10-2023)
    “…Organic Cation Transporter 1 (OCT1) plays a crucial role in hepatic metabolism by mediating the uptake of a range of metabolites and drugs. Genetic variations…”
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    Journal Article