Search Results - "Quinn, Ada"
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The efficacy of the analgesic GlyT2 inhibitor, ORG25543, is determined by two connected allosteric sites
Published in Journal of neurochemistry (01-09-2024)“…Glycine Transporter 2 (GlyT2) inhibitors have shown considerable potential as analgesics for the treatment of neuropathic pain but also display considerable…”
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Journal Article -
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Structural basis of promiscuous substrate transport by Organic Cation Transporter 1
Published in Nature communications (11-10-2023)“…Organic Cation Transporter 1 (OCT1) plays a crucial role in hepatic metabolism by mediating the uptake of a range of metabolites and drugs. Genetic variations…”
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Journal Article