Search Results - "Quinlin, Imelda S"
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MHC-Unrestricted Lysis of MUC1-Expressing Cells by Human Peripheral Blood Mononuclear Cells
Published in Immunological investigations (01-01-2008)“…Many human adenocarcinomas can be killed in vitro by targeted cytotoxic T-lymphocytes (CTL); however, major histocompatibility complex (MHC)-restrictions are…”
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Immunotherapy with IL-10- and IFN-γ-producing CD4 effector cells modulate “Natural” and “Inducible” CD4 TReg cell subpopulation levels: observations in four cases of patients with ovarian cancer
Published in Cancer Immunology, Immunotherapy (01-06-2012)“…Adoptive T cell therapy for cancer patients optimally requires participation of CD4 T cells. In this phase I/II study, we assessed the therapeutic effects of…”
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Cytotoxic T-lymphocyte Immunotherapy for Ovarian Cancer: A Pilot Study
Published in Journal of immunotherapy (1997) (01-02-2012)“…The objective was to evaluate the toxicity and feasibility of intraperitoneal infusion of tumor-specific cytotoxic T lymphocytes (CTL) as therapy for recurrent…”
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Autologous MUC1-specific Th1 effector cell immunotherapy induces differential levels of systemic TReg cell subpopulations that result in increased ovarian cancer patient survival
Published in Clinical immunology (Orlando, Fla.) (01-12-2009)“…Abstract Adoptive T cell immunotherapy using autologous lymphocytes is a viable treatment for patients with cancer and requires participation of Ag-specific…”
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Dendritic cells enhance the activity of human MUC1-stimulated mononuclear cells against breast cancer
Published in Oncoimmunology (01-02-2013)“…Dendritic cells (DCs) are among the most potent antigen-presenting cells (APCs), stimulating peripheral blood mononuclear cells (PBMCs) to generate…”
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Tumor Burden Influences Cytotoxic T Cell Development in Metastatic Breast Cancer Patients-A Phase I II Study
Published in Immunological investigations (01-11-2009)“…The influence of tumor burden on the generation of tumor antigen-specific cytotoxic T-lymphocytes (CTL) was investigated in a phase I II clinical adoptive…”
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Number of Treatment Cycles Influences Development of Cytotoxic T Cells in Metastatic Breast Cancer Patients - A Phase I II Study
Published in Immunological investigations (2010)“…The influence of the number of apheresis-stimulation-infusion(s) cycles, and the time in culture before the infusion (one vs. two weeks), on the generation of…”
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Adoptive immunotherapy of mucin1 expressing adenocarcinomas with mucin1 stimulated human peripheral blood mononuclear cells
Published in International journal of molecular medicine (01-04-2002)“…Mucin1 stimulated hematopoietic mononuclear cells (M1SHMC) from patients with breast cancer, adoptively transferred to non-obese diabetic, severe combined…”
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Immunotherapy with IL-10- and IFN-[gamma]-producing CD4 effector cells modulate "Natural" and "Inducible" CD4 TReg cell subpopulation levels: observations in four cases of patients with ovarian cancer
Published in Cancer immunology, immunotherapy (01-06-2012)“…Adoptive T cell therapy for cancer patients optimally requires participation of CD4 T cells. In this phase I/II study, we assessed the therapeutic effects of…”
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Autologous MUC1-Specific Th1 Effector Cell Immunotherapy Induce Differential Levels of Systemic TReg Cell Subpopulations That Result in Increased Ovarian Cancer Patient Survival
Published in Clinical immunology (Orlando, Fla.) (16-09-2009)“…Adoptive T cell immunotherapy using autologous lymphocytes is a viable treatment for patients with cancer and requires participation of Ag-specific CD4 and CD8…”
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Retention of immunogenicity produced by mucin1 peptides with glycosylation site substitutions
Published in Immunopharmacology and immunotoxicology (01-12-2010)“…Mucin1 (MUC1) with altered glycosylation behaves as an antigen unique to adenocarcinomas (ADCs). As a step toward DNA vaccines, the goal of this work was to…”
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Retention of immunogenicity produced by mucin 1 peptides with glycosylation site substitutions
Published in Immunopharmacology and immunotoxicology (01-12-2010)“…Mucin1 (MUC1) with altered glycosylation behaves as an antigen unique to adenocarcinomas (ADCs). As a step toward DNA vaccines, the goal of this work was to…”
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