Search Results - "Quinlan, TR"

eNOS-deficient mice show reduced pulmonary vascular proliferation and remodeling to chronic hypoxia by Quinlan, T R, Li, D, Laubach, V E, Shesely, E G, Zhou, N, Johns, R A

“…Pulmonary hypertension is characterized by structural and morphological changes to the lung vasculature. To determine the potential role of nitric oxide in the…”
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Increased epidermal growth factor-receptor protein in a human mesothelial cell line in response to long asbestos fibers by Pache, JC, Janssen, YM, Walsh, ES, Quinlan, TR, Zanella, CL, Low, RB, Taatjes, DJ, Mossman, BT

“…Epidermal growth factor (EGF) is a potent mitogen for human mesothelial cells, and autophosphorylation of the EGF receptor (EGF-R) occurs in these cell types…”
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Asbestos causes translocation of p65 protein and increases NF-kappa B DNA binding activity in rat lung epithelial and pleural mesothelial cells by Janssen, YM, Driscoll, KE, Howard, B, Quinlan, TR, Treadwell, M, Barchowsky, A, Mossman, BT

“…The mechanisms of cell signaling and altered gene expression by asbestos, a potent inflammatory, fibrogenic, and carcinogenic agent, are unclear. Activation of…”
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Mechanisms of Asbestos-induced Nitric Oxide Production by Rat Alveolar Macrophages in Inhalation and in vitro Models by Quinlan, Timothy R, BeruBe, Kelly A, Hacker, Miles P, Taatjes, Douglas J, Timblin, Cynthia R, Goldberg, Jonathan, Kimberley, Priscilla, O’Shaughnessy, Patrick, Hemenway, David, Torino, Jennifer, Jimenez, Luis A, Mossman, Brooke T

“…To evaluate the contribution of reactive nitrogen species to inflammation by asbestos, Fischer 344 rats were exposed to crocidolite or chrysotile asbestos by…”
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Apoptosis is observed in mesothelial cells after exposure to crocidolite asbestos by BéruBé, K A, Quinlan, T R, Fung, H, Magae, J, Vacek, P, Taatjes, D J, Mossman, B T

“…Asbestos causes protracted, dose-dependent increases in steady-state mRNA levels of the proto-oncogenes c-fos and c-jun, and AP-1 DNA-binding activity in…”
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TNFα and increased chemokine expression in rat lung after particle exposure by Driscoll, Kevin E., Hassenbein, Diana G., Carter, Janet M., Kunkel, Steven L., Quinlan, Timothy R., Mossman, Brooke T.

“…Macrophage inflammatory protein 2 (MIP-2) and CINC (Cytokine-Induced-Neutrophil-Chemoattractant) are members of the chemokine family of inflammatory and…”
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Patterns of inflammation, cell proliferation, and related gene expression in lung after inhalation of chrysotile asbestos by Quinlan, TR, BeruBe, KA, Marsh, JP, Janssen, YM, Taishi, P, Leslie, KO, Hemenway, D, O'Shaughnessy, PT, Vacek, P, Mossman, BT

“…Biochemical and molecular markers of inflammation, cell proliferation, and pulmonary fibrosis were studied in lungs and bronchoalveolar lavage preparations…”
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Oxygen Radicals and Asbestos-Mediated Disease by Quinlan, Timothy R., Marsh, Joanne P., Janssen, Yvonne M. W., Borm, Paul A., Mossman, Brooke T.

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Comparative Proliferative and Histopathologic Changes in Rat Lungs after Inhalation of Chrysotile or Crocidolite Asbestos by BéruBé, Kelly A., Quinlan, Timothy R., Moulton, Gerald, Hemenway, David, O'Shaughnessy, Patrick, Vacek, Pamela, Mossman, Brooke T.

“…Patterns of cell proliferation in lung and pleura and development of histopathologic lesions were studied in lungs from Fischer 344 rats after inhalation…”
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Dose-responsive increases in pulmonary fibrosis after inhalation of asbestos by Quinlan, T R, Marsh, J P, Janssen, Y M, Leslie, K O, Hemenway, D, Vacek, P, Mossman, B T

“…We focused here on steady-state mRNA levels of genes involved in antioxidant defense, i.e., manganese superoxide dismutase and copper-zinc superoxide…”
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Alterations in nitric oxide synthase isoform expression in NOS knockout mice exposed to normoxia or hypoxia by Quinlan, T R, Laubach, V, Zhou, N, Johns, R A

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A review of outcomes after operative fixation of clavicular fractures over a 10-year period—a single tertiary trauma unit experience by Fitzgerald, Eilis M., Moore, David M., Quinlan, John F.

“…Early definitive fixation of clavicular fractures is rising in popularity when compared with conservative management. Despite this, the relative risk of…”
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