Search Results - "Quinlan, Margot E"

p53-cofactor JMY is a multifunctional actin nucleation factor by Coutts, Amanda S, Zuchero, J. Bradley, Mullins, R. Dyche, Quinlan, Margot E, Thangue, Nicholas B. La

“…Many cellular structures are assembled from networks of actin filaments, and the architecture of these networks depends on the mechanism by which the filaments…”
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The Role of Formin Tails in Actin Nucleation, Processive Elongation, and Filament Bundling by Vizcarra, Christina L., Bor, Batbileg, Quinlan, Margot E.

“…Formins are multidomain proteins that assemble actin in a wide variety of biological processes. They both nucleate and remain processively associated with…”
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Regulatory interactions between two actin nucleators, Spire and Cappuccino by Quinlan, Margot E, Hilgert, Susanne, Bedrossian, Anaid, Mullins, R. Dyche, Kerkhoff, Eugen

“…Spire and Cappuccino are actin nucleation factors that are required to establish the polarity of Drosophila melanogaster oocytes. Their mutant phenotypes are…”
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Interaction between Microtubules and the Drosophila Formin Cappuccino and Its Effect on Actin Assembly by Roth-Johnson, Elizabeth A., Vizcarra, Christina L., Bois, Justin S., Quinlan, Margot E.

“…Formin family actin nucleators are potential coordinators of the actin and microtubule cytoskeletons, as they can both nucleate actin filaments and bind…”
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Structure and function of the interacting domains of Spire and Fmn-family formins by Vizcarra, Christina L, Kreutz, Barry, Rodal, Avital A, Toms, Angela V, Lu, Jun, Zheng, Wei, Quinlan, Margot E, Eck, Michael J

“…Evidence for cooperation between actin nucleators is growing. The WH2-containing nucleator Spire and the formin Cappuccino interact directly, and both are…”
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Drosophila Spire is an actin nucleation factor by Quinlan, M.E, Heuser, J.E, Kerkhoff, E, Mullins, R.D

“…The actin cytoskeleton is essential for many cellular functions including shape determination, intracellular transport and locomotion. Previous work has…”
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Cytoplasmic Streaming in the Drosophila Oocyte by Quinlan, Margot E

“…Objects are commonly moved within the cell by either passive diffusion or active directed transport. A third possibility is advection, in which objects within…”
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Three-dimensional structural dynamics of myosin V by single-molecule fluorescence polarization by Goldman, Yale E, Forkey, Joseph N, Quinlan, Margot E, Alexander Shaw, M, Corrie, John E. T

“…The structural change that generates force and motion in actomyosin motility has been proposed to be tilting of the myosin light chain domain, which serves as…”
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Direct interaction between two actin nucleators is required in Drosophila oogenesis by Quinlan, Margot E

“…Controlled actin assembly is crucial to a wide variety of cellular processes, including polarity establishment during early development. The recently…”
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Formins by Valencia, Dylan A., Quinlan, Margot E.

“…Actin is one of the most abundant proteins in eukaryotes. Discovered in muscle and described as far back as 1887, actin was first purified in 1942. It plays…”
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Methylation and phosphorylation of formin homology domain proteins (Fhod1 and Fhod3) by protein arginine methyltransferase 7 (PRMT7) and Rho kinase (ROCK1) by Lowe, Troy L., Valencia, Dylan A., Velasquez, Vicente E., Quinlan, Margot E., Clarke, Steven G.

“…Protein post-translational modifications (PTMs) can regulate biological processes by altering an amino acid’s bulkiness, charge, and hydrogen bonding…”
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Formin tails act as a switch, inhibiting or enhancing processive actin elongation by Bremer, Kathryn V, Wu, Carolyn, Patel, Aanand A, He, Kevin L, Grunfeld, Alex M, Chanfreau, Guillaume F, Quinlan, Margot E

“…Formins are large, multidomain proteins that nucleate new actin filaments and accelerate elongation through a processive interaction with the barbed ends of…”
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Orientation of the Myosin Light Chain Region by Single Molecule Total Internal Reflection Fluorescence Polarization Microscopy by Quinlan, Margot E., Forkey, Joseph N., Goldman, Yale E.

“…To study the orientation and dynamics of myosin, we measured fluorescence polarization of single molecules and ensembles of myosin decorating actin filaments…”
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Spire stimulates nucleation by Cappuccino and binds both ends of actin filaments by Bradley, Alexander O, Vizcarra, Christina L, Bailey, Hannah M, Quinlan, Margot E

“…The actin nucleators Spire and Cappuccino synergize to promote actin assembly, but the mechanism of their synergy is controversial. Together these proteins…”
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Drosophila and human FHOD family formin proteins nucleate actin filaments by Patel, Aanand A., Oztug Durer, Zeynep A., van Loon, Aaron P., Bremer, Kathryn V., Quinlan, Margot E.

“…Formins are a conserved group of proteins that nucleate and processively elongate actin filaments. Among them, the formin homology domain–containing protein…”
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Actin Cross-Linking Toxin Is a Universal Inhibitor of Tandem-Organized and Oligomeric G-Actin Binding Proteins by Kudryashova, Elena, Heisler, David B., Williams, Blake, Harker, Alyssa J., Shafer, Kyle, Quinlan, Margot E., Kovar, David R., Vavylonis, Dimitrios, Kudryashov, Dmitri S.

“…Delivery of bacterial toxins to host cells is hindered by host protective barriers. This obstruction dictates a remarkable efficiency of toxins, a single copy…”
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Actin filament assembly by bacterial factors VopL/F: Which end is up? by Vizcarra, Christina L, Quinlan, Margot E

“…Competing models have been proposed for actin filament nucleation by the bacterial proteins VopL/F. In this issue, Burke et al. (2017…”
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The neuron-specific formin Delphilin nucleates nonmuscle actin but does not enhance elongation by Silkworth, William T, Kunes, Kristina L, Nickel, Grace C, Phillips, Martin L, Quinlan, Margot E, Vizcarra, Christina L

“…The formin Delphilin binds the glutamate receptor, GluRδ2, in dendritic spines of Purkinje cells. Both proteins play a role in learning. To understand how…”
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Drosophila Cappuccino alleles provide insight into formin mechanism and role in oogenesis by Yoo, Haneul, Roth-Johnson, Elizabeth A, Bor, Batbileg, Quinlan, Margot E

“…During Drosophila development, the formin actin nucleator Cappuccino (Capu) helps build a cytoplasmic actin mesh throughout the oocyte. Loss of Capu leads to…”
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The Diaphanous-Related Formins Promote Protrusion Formation and Cell-to-Cell Spread of Listeria monocytogenes by Fattouh, Ramzi, Kwon, Hyunwoo, Czuczman, Mark A., Copeland, John W., Pelletier, Laurence, Quinlan, Margot E., Muise, Aleixo M., Higgins, Darren E., Brumell, John H.

“…The Gram-positive bacterium Listeria monocytogenes is a facultative intracellular pathogen whose virulence depends on its ability to spread from cell to cell…”
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