Search Results - "Quillen, Sarah"
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Astrocyte responses to experimental glaucoma in mouse optic nerve head
Published in PloS one (21-08-2020)“…To delineate responses of optic nerve head astrocytes to sustained intraocular pressure (IOP) elevation in mice. We elevated IOP for 1 day to 6 weeks by…”
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2
Comparison of the Biomechanics of the Mouse Astrocytic Lamina Cribrosa Between Glaucoma and Optic Nerve Crush Models
Published in Investigative ophthalmology & visual science (01-12-2023)“…The strain response of the mouse astrocytic lamina (AL) to an ex vivo mechanical test was compared between two protocols: eyes that underwent sustained…”
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3
The role of aquaporin-4 in optic nerve head astrocytes in experimental glaucoma
Published in PloS one (02-02-2021)“…To study aquaporin channel expression in astrocytes of the mouse optic nerve (ON) and the response to IOP elevation in mice lacking aquaporin 4 (AQP4 null)…”
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4
Aquaporin 4 is not present in normal porcine and human lamina cribrosa
Published in PloS one (16-06-2022)“…Aquaporin 4 is absent from astrocytes in the rodent optic nerve head, despite high expression in the retina and myelinated optic nerve. The purpose of this…”
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5
Regional Gene Expression in the Retina, Optic Nerve Head, and Optic Nerve of Mice with Optic Nerve Crush and Experimental Glaucoma
Published in International journal of molecular sciences (01-09-2023)“…A major risk factor for glaucomatous optic neuropathy is the level of intraocular pressure (IOP), which can lead to retinal ganglion cell axon injury and cell…”
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6
Quantitative Microstructural Analysis of Cellular and Tissue Remodeling in Human Glaucoma Optic Nerve Head
Published in Investigative ophthalmology & visual science (21-10-2022)“…To measure quantitatively changes in lamina cribrosa (LC) cell and connective tissue structure in human glaucoma eyes. We studied 27 glaucoma and 19…”
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Effects of experimental glaucoma in Lama1nmf223 mutant mice
Published in Experimental eye research (01-01-2023)“…To identify changes in response to experimental intraocular pressure (IOP) elevation associated with the laminin α1 nmf223 mutation in mice. Laminin mutant…”
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8
Mechanical strain in the mouse astrocytic lamina increases after exposure to recombinant trypsin
Published in Acta biomaterialia (01-06-2023)“…The responses of astrocytes in the optic nerve head (ONH) to mechanical and biochemical stimuli are important to understanding the degeneration of retinal…”
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Effects of experimental glaucoma in Lama1 mutant mice
Published in Experimental eye research (01-01-2023)Get full text
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10
Role of the Internal Limiting Membrane in Structural Engraftment and Topographic Spacing of Transplanted Human Stem Cell-Derived Retinal Ganglion Cells
Published in Stem cell reports (12-01-2021)“…Retinal ganglion cell (RGC) replacement holds potential for restoring vision lost to optic neuropathy. Transplanted RGCs must undergo neuroretinal integration…”
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11
Effects of experimental glaucoma in Lama1 nmf223 mutant mice
Published in Experimental eye research (01-01-2023)“…To identify changes in response to experimental intraocular pressure (IOP) elevation associated with the laminin α1 nmf223 mutation in mice. Laminin mutant…”
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12
Aquaporin 4 is not present in normal porcine and human lamina cribrosa
Published in PloS one (01-01-2022)“…Aquaporin 4 is absent from astrocytes in the rodent optic nerve head, despite high expression in the retina and myelinated optic nerve. The purpose of this…”
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13
Ion-Complex Microcrystal Formulation Provides Sustained Delivery of a Multimodal Kinase Inhibitor from the Subconjunctival Space for Protection of Retinal Ganglion Cells
Published in Pharmaceutics (01-05-2021)“…Glaucoma is the leading cause of irreversible blindness worldwide. Elevated intraocular pressure (IOP) is one of the major risk factors for glaucoma onset and…”
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14
Rebuilding Our Power Without Procedural Safeguards: A Federal Response to the 2005 Hurricanes that Outlasted the "Emergency"
Published in The Harvard environmental law review : HELR (01-01-2008)“…Various aspects related to the 2005 Hurricane were discussed. The hurricanes threatened to damage much more than homes, natural gas pipelines, and other…”
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