Search Results - "Quignard, JF"
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Quercetin potentiates insulin secretion and protects INS-1 pancreatic [beta]-cells against oxidative damage via the ERK1/2 pathway
Published in British journal of pharmacology (01-10-2010)“…BACKGROUND AND PURPOSE Quercetin lowers plasma glucose, normalizes glucose tolerance tests and preserves pancreatic [beta]-cell integrity in diabetic rats…”
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Quercetin potentiates insulin secretion and protects INS‐1 pancreatic β‐cells against oxidative damage via the ERK1/2 pathway
Published in British journal of pharmacology (01-10-2010)“…BACKGROUND AND PURPOSE Quercetin lowers plasma glucose, normalizes glucose tolerance tests and preserves pancreatic β‐cell integrity in diabetic rats. However,…”
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Involvement of oxidative stress and calcium signaling in airborne particulate matter - induced damages in human pulmonary artery endothelial cells
Published in Toxicology in vitro (01-12-2017)“…Recent studies have revealed that particulate matter (PM) exert deleterious effects on vascular function. Pulmonary artery endothelial cells (HPAEC), which are…”
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Phosphoinositide 3-Kinase γ Mediates Angiotensin II-induced Stimulation of L-type Calcium Channels in Vascular Myocytes
Published in The Journal of biological chemistry (31-08-2001)“…Previous results have shown that in rat portal vein myocytes the βγ dimer of the G13 protein transduces the angiotensin II-induced stimulation of calcium…”
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Phosphoinositide 3-Kinase Isoforms Selectively Couple Receptors to Vascular L-Type Ca2+ Channels
Published in Circulation research (12-10-2001)“…Heterodimeric class I phosphoinositide 3-kinase (PI3K) has been shown to be involved in the stimulation of voltage-gated Ca channels by various mediators. In…”
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Potassium ions and endothelium‐derived hyperpolarizing factor in guinea‐pig carotid and porcine coronary arteries
Published in British journal of pharmacology (01-05-1999)“…Experiments were designed to determine in two arteries (the guinea‐pig carotid and the porcine coronary arteries) whether or not the endothelium‐derived…”
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Transient down-regulation of L-type Ca2+ channel and dystrophin expression after balloon injury in rat aortic cells
Published in Cardiovascular research (2001)Get full text
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K+ Channels in Cultured Bovine Retinal Pericytes: Effects of β-Adrenergic Stimulation
Published in Journal of cardiovascular pharmacology (01-09-2003)“…Retinal pericytes are key cells involved in the regulation of retinal blood flow. The purpose of this work was to identify the K channel population expressed…”
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Role of endothelial cell hyperpolarization in EDHF‐mediated responses in the guinea‐pig carotid artery
Published in British journal of pharmacology (01-03-2000)“…Experiments were performed to identify the potassium channels involved in the acetylcholine‐induced endothelium‐dependent hyperpolarization of the guinea‐pig…”
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Stimulation of L-type Ca2+ channels by inositol pentakis- and hexakisphosphates in rat vascular smooth muscle cells
Published in The Journal of physiology (15-06-2003)“…The electrophysiological effects of d -myo-inositol 1,3,4,5,6-pentakisphosphate (Ins P 5 ) and d -myo-inositol hexakisphosphate (Ins P 6 ), which represent the…”
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Voltage-gated calcium channel currents in human coronary myocytes. Regulation by cyclic GMP and nitric oxide
Published in The Journal of clinical investigation (15-01-1997)“…Voltage-gated Ca2+ channels contribute to the maintenance of contractile tone in vascular myocytes and are potential targets for vasodilating agents. There is…”
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A novel tetrodotoxin-sensitive Na+ current in cultured human coronary myocytes
Published in Circulation research (01-03-1997)“…Voltage-gated Na+ currents (INaS) are usually not found in arterial smooth muscle. We enzymatically isolated myocytes from the media of left coronary arteries…”
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Regulation of Ca2+ Homeostasis by Atypical Na+ Currents in Cultured Human Coronary Myocytes
Published in Circulation research (01-10-1999)“…Primary cultured human coronary myocytes (HCMs) derived from ischemic human hearts express an atypical voltage-gated tetrodotoxin (TTX)-sensitive sodium…”
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3-Morpholinosydnonimine (SIN-1) and K + channels in smooth muscle cells of the rabbit and guinea pig carotid arteries
Published in European journal of pharmacology (30-06-2000)“…Experiments were designed to determine the subtype of K + channels activated by the nitrovasodilator 3-morpholinosydnonimine (SIN-1) in smooth muscle cells of…”
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Endothelium-Dependent Hyperpolarization to Acetylcholine in Carotid Artery of Guinea Pig: Role of Lipoxygenase
Published in Journal of cardiovascular pharmacology (01-09-2002)“…This study was designed to determine whether lipoxygenase-dependent metabolites of arachidonic acid are involved in the endothelium-dependent hyperpolarization…”
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Site-directed mutagenesis of a calcium binding site modifies specifically the different biochemical properties of annexin I
Published in Protein engineering (01-05-1994)“…All the functions of annexins in vitro as well as in vivo are mediated and probably regulated by calcium. We have used recombinant annexin I, synthesized by…”
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Interdependence of phospholipid specificity and calcium binding in annexin I as shown by site-directed mutagenesis
Published in Biochimica et biophysica acta (13-04-1994)“…We have mutated the lysine 128 of domain II of annexin I, which flanks a putative calcium-binding loop, into a glutamic acid residue. The properties of the…”
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