Turnera ulmifolia L. (Turneraceae): Preliminary study of its antioxidant activity

Turnera ulmifolia L. (Turneraceae): Preliminary study of its antioxidant activity

Turnera ulmifolia L. is used in Brazilian folk medicine as an anti-inflammatory. Since this activity may be correlated with the presence of antioxidant compounds, a leaf extract was evaluated for its radical scavenging capacity (RSC). The in vitro RSC of a 50% hydroethanolic (HE) extract was evaluat...

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Bibliographic Details
Published in:Bioresource technology Vol. 97; no. 12; pp. 1387 - 1391
Main Authors: Nascimento, M.A., Silva, A.K., França, L.C.B., Quignard, E.L.J., López, J.A., Almeida, M.G.
Format: Journal Article
Language:English
Published: Oxford Elsevier Ltd 01-08-2006
Elsevier Science
Subjects:
Animals
Antioxidant activity
Antioxidants - metabolism
Antioxidants - pharmacology
beta Carotene - metabolism
Biological and medical sciences
Biotechnology - methods
Brain - metabolism
Drug Design
Free Radicals
General pharmacology
Lipid Peroxidation
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plant extracts
Plant Extracts - pharmacology
Plant Leaves
Rats
Rats, Wistar
Thiobarbituric Acid Reactive Substances
Turnera - metabolism
Turnera ulmifolia
Turnera ulmifolia L
Turneraceae
β-carotene bleaching
Lipid peroxidation
β-carotene bleaching
Turnera ulmifolia L
Antioxidant activity
Plant extracts
Turneraceae
Antiinflammatory agent
Lipids
Antioxidant
Tissue extract
Folk medicine
Bleaching
Dicotyledones
Angiospermae
Plant origin
Spermatophyta
Betacarotene
Peroxidation
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Summary:Turnera ulmifolia L. is used in Brazilian folk medicine as an anti-inflammatory. Since this activity may be correlated with the presence of antioxidant compounds, a leaf extract was evaluated for its radical scavenging capacity (RSC). The in vitro RSC of a 50% hydroethanolic (HE) extract was evaluated by β-carotene/linoleic acid coupled oxidation system for the inhibition of oxidation and the lipid peroxidation inhibition in rat brain homogenates, using thiobarbituric acid reactive substances (TBARS) and chemiluminescence (CL). Results indicated, through peroxidation suppression, that this extract exhibited greater antioxidative activity (77.4% ± 10%) than α-tocopherol (58.4% ± 3.7%). TBARS and CL inhibition was concentration-dependent and Q 1/2 values were 8.2 and 6.0 μg/mL for TBARS and CL, respectively. For α-tocopherol these values were 7.1 μg/mL (TBARS) and 9.8 μg/mL (CL). Phenolic compounds may be responsible for this antioxidant capacity.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
ISSN:0960-8524
1873-2976
DOI:10.1016/j.biortech.2005.07.009