Search Results - "Quevedo, Mario Alfredo"

Current trends in molecular modeling methods applied to the study of cyclodextrin complexes by Quevedo, Mario Alfredo, Zoppi, Ariana

“…In this review the authors present an overview of different molecular modeling campaigns dealing with the study and characterization of cyclodextrins (CDs)…”
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Synthesis and characterization of supramolecular systems containing nifedipine, β-cyclodextrin and aspartic acid by Cerutti, Juan Pablo, Quevedo, Mario Alfredo, Buhlman, Natalia, Longhi, Marcela Raquel, Zoppi, Ariana

“…[Display omitted] •Complexes of nifedipine with β-cyclodextrin and aspartic acid were prepared.•Multicomponent complex formation increase the aqueous…”
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Structure-Aided Computational Design of Triazole-Based Targeted Covalent Inhibitors of Cruzipain by Cerutti, Juan Pablo, Diniz, Lucas Abreu, Santos, Viviane Corrêa, Vilchez Larrea, Salomé Catalina, Alonso, Guillermo Daniel, Ferreira, Rafaela Salgado, Dehaen, Wim, Quevedo, Mario Alfredo

“…Cruzipain (CZP), the major cysteine protease present in , the ethiological agent of Chagas disease, has attracted particular attention as a therapeutic target…”
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Increasing Doxycycline Hyclate Photostability by Complexation with β-Cyclodextrin by Kogawa, Ana Carolina, Zoppi, Ariana, Quevedo, Mario Alfredo, Nunes Salgado, Hérida Regina, Longhi, Marcela Raquel

“…Doxycycline hyclate (DOX) is a highly photosensitive drug, a feature that limits the stability of the corresponding dosage forms. The main objectives of this…”
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Synthesis of a novel analog of calcitriol and its biological evaluation as antitumor agent by Ferronato, María Julia, Obiol, Diego Javier, Alonso, Eliana Noelia, Guevara, Josefina Alejandra, Grioli, Silvina Mariela, Mascaró, Marilina, Rivadulla, Marcos Lois, Martínez, Andrea, Gómez, Generosa, Fall, Yagamare, Quevedo, Mario Alfredo, Curino, Alejandro Carlos, Facchinetti, María Marta

“…[Display omitted] •ML-344 is a novel calcitriol analog with amide and carboxyl groups in its side chain.•ML-344 has antitumor activity in cell lines…”
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Antitumoral effects of the alkynylphosphonate analogue of calcitriol EM1 on glioblastoma multiforme cells by Ferronato, María Julia, Alonso, Eliana Noelia, Salomón, Débora Gisele, Fermento, María Eugenia, Gandini, Norberto Ariel, Quevedo, Mario Alfredo, Mascaró, Evangelina, Vitale, Cristian, Fall, Yagamare, Facchinetti, María Marta, Curino, Alejandro Carlos

“…[Display omitted] •EM1 exerts a differential effect on the viability of GBM cells and primary astrocytes.•EM1 has anti-proliferative effects on T98G by…”
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Homodiselenacalix[4]arenes: Molecules with Unique Channelled Crystal Structures by Thomas, Joice, Dobrzańska, Liliana, Van Meervelt, Luc, Quevedo, Mario Alfredo, Woźniak, Krzysztof, Stachowicz, Marcin, Smet, Mario, Maes, Wouter, Dehaen, Wim

“…A synthetic route towards homodiselenacalix[4]arene macrocycles is presented, based on the dynamic covalent chemistry of diselenides. The calixarene inner rim…”
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The UVB1 Vitamin D analogue inhibits colorectal carcinoma progression by Ferronato, María Julia, Alonso, Eliana Noelia, Gandini, Norberto Ariel, Fermento, María Eugenia, Villegas, María Emilia, Quevedo, Mario Alfredo, Arévalo, Julián, López Romero, Alejandro, Rivadulla, Marcos Lois, Gómez, Generosa, Fall, Yagamare, Facchinetti, María Marta, Curino, Alejandro Carlos

“…[Display omitted] •UVB1 induces apoptotic cell death of HCT116 colorectal carcinoma cells.•UVB1 inhibits cellular migration and invasion in colorectal…”
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In vitro and in vivo pharmacokinetic characterization of two novel prodrugs of zidovudine by Quevedo, Mario Alfredo, Briñón, Margarita Cristina

“…This work deals with the in vitro and in vivo pharmacokinetic characterization of 3′-azido-2′,3′-dideoxy-5′- O-oxalatoylthymidine (AZT-Ac) and…”
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Design, Synthesis, and Biological Evaluation of New Type of Gemini Analogues with a Cyclopropane Moiety in Their Side Chain by Gómez-Bouzó, Uxía, Peluso-Iltis, Carole, Santalla, Hugo, Quevedo, Mario Alfredo, Verlinden, Lieve, Verstuyf, Annemieke, Fall, Yagamare, Gómez, Generosa, Rochel, Natacha

“…We synthesized two new gemini analogues, UG-480 and UG-481, that incorporate a modified longer side chain containing a cyclopropane group. The evaluation of…”
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