Search Results - "Querfeld, Uwe"

Mycophenolate mofetil for sustained remission in nephrotic syndrome by Querfeld, Uwe, Weber, Lutz T.

“…The clinical application of mycophenolate mofetil (MMF) has significantly widened beyond the prophylaxis of acute and chronic rejections in solid organ…”
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The cardiovascular phenotype of adult patients with phenylketonuria by Azabdaftari, Aline, van der Giet, Markus, Schuchardt, Mirjam, Hennermann, Julia B, Plöckinger, Ursula, Querfeld, Uwe

“…Patients with Phenylketonuria (PKU) are exposed to multiple cardiovascular risk factors, but the clinical significance of these abnormalities is yet unknown…”
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Aortic Pulse Wave Velocity in Healthy Children and Adolescents: Reference Values for the Vicorder Device and Modifying Factors by Thurn, Daniela, Doyon, Anke, Sözeri, Betul, Bayazit, Aysun K., Canpolat, Nur, Duzova, Ali, Querfeld, Uwe, Schmidt, Bernhard M.W., Schaefer, Franz, Wühl, Elke, Melk, Anette

“…BACKGROUND Aortic pulse wave velocity (PWV), an indicator of arterial stiffness, independently predicts cardiovascular mortality risk in adults. Arterial…”
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The matrix metalloproteinases 2 and 9 initiate uraemic vascular calcifications by Hecht, Eva, Freise, Christian, Websky, Karoline V, Nasser, Hamoud, Kretzschmar, Nadja, Stawowy, Philipp, Hocher, Berthold, Querfeld, Uwe

“…The matrix metalloproteinases (MMP) MMP-2 and MMP-9 are physiological regulators of vascular remodelling. Their dysregulation could contribute to vascular…”
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Chronic kidney disease induces a systemic microangiopathy, tissue hypoxia and dysfunctional angiogenesis by Prommer, Hans-Ulrich, Maurer, Johannes, von Websky, Karoline, Freise, Christian, Sommer, Kerstin, Nasser, Hamoud, Samapati, Rudi, Reglin, Bettina, Guimarães, Pedro, Pries, Axel Radlach, Querfeld, Uwe

“…Chronic kidney disease (CKD) is associated with excessive mortality from cardiovascular disease (CVD). Endothelial dysfunction, an early manifestation of CVD,…”
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Serum indoxyl sulfate concentrations associate with progression of chronic kidney disease in children by Holle, Johannes, Kirchner, Marietta, Okun, Jürgen, Bayazit, Aysun K, Obrycki, Lukasz, Canpolat, Nur, Bulut, Ipek Kaplan, Azukaitis, Karolis, Duzova, Ali, Ranchin, Bruno, Shroff, Rukshana, Candan, Cengiz, Oh, Jun, Klaus, Günter, Lugani, Francesca, Gimpel, Charlotte, Büscher, Rainer, Yilmaz, Alev, Baskin, Esra, Erdogan, Hakan, Zaloszyc, Ariane, Özcelik, Gül, Drozdz, Dorota, Jankauskiene, Augustina, Nobili, Francois, Melk, Anette, Querfeld, Uwe, Schaefer, Franz

“…The uremic toxins indoxyl sulfate (IS) and p-cresyl sulfate (pCS) accumulate in patients with chronic kidney disease (CKD) as a consequence of altered gut…”
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Quantitative Histomorphometry of the Healthy Peritoneum by Schaefer, Betti, Bartosova, Maria, Macher-Goeppinger, Stephan, Ujszaszi, Akos, Wallwiener, Markus, Nyarangi-Dix, Joanne, Sallay, Peter, Burkhardt, Dorothea, Querfeld, Uwe, Pfeifle, Viktoria, Lahrmann, Bernd, Schwenger, Vedat, Wühl, Elke, Holland-Cunz, Stefan, Schaefer, Franz, Schmitt, Claus P.

“…The peritoneum plays an essential role in preventing abdominal frictions and adhesions and can be utilized as a dialysis membrane. Its physiological…”
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CNNM2, Encoding a Basolateral Protein Required for Renal Mg2+ Handling, Is Mutated in Dominant Hypomagnesemia by STUIVER, Marchel, LAINEZ, Sergio, QUERFELD, Uwe, WILLNOW, Thomas E, NEMEC, Vladimir, WAGNER, Carsten A, HOENDEROP, Joost G, DEVUYST, Olivier, KNOERS, Nine V. A. M, BINDELS, René J, MEIJ, Iwan C, MÜLLER, Dominik, WILL, Constanze, TERRYN, Sara, GÜNZEL, Dorothee, DEBAIX, Huguette, SOMMER, Kerstin, KOPPLIN, Kathrin, THUMFART, Julia, KAMPIK, Nicole B

“…Familial hypomagnesemia is a rare human disorder caused by renal or intestinal magnesium (Mg(2+)) wasting, which may lead to symptoms of Mg(2+) depletion such…”
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Determinants of growth after kidney transplantation in prepubertal children by Grohs, Julia, Rebling, Rainer-Maria, Froede, Kerstin, Hmeidi, Kristin, Pavičić, Leo, Gellermann, Jutta, Müller, Dominik, Querfeld, Uwe, Haffner, Dieter, Živičnjak, Miroslav

“…Background Short stature is a frequent complication after pediatric kidney transplantation (KT). Whether the type of transplantation and prior treatment with…”
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Effects of Chronic Kidney Disease on Nanomechanics of the Endothelial Glycocalyx Are Mediated by the Mineralocorticoid Receptor by Fels, Benedikt, Beyer, Arne, Cazaña-Pérez, Violeta, Giraldez, Teresa, Navarro-González, Juan F, Alvarez de la Rosa, Diego, Schaefer, Franz, Bayazit, Aysun K, Obrycki, Łukasz, Ranchin, Bruno, Holle, Johannes, Querfeld, Uwe, Kusche-Vihrog, Kristina

“…Endothelial mechanics control vascular reactivity and are regulated by the mineralocorticoid receptor (MR) and its downstream target, the epithelial Na channel…”
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Vitamin D deficiency and toxicity in chronic kidney disease: in search of the therapeutic window by Querfeld, Uwe, Mak, Robert H.

“…Both vitamin D deficiency and vitamin D toxicity are associated with cardiovascular complications in chronic kidney disease (CKD). Clinical and experiment data…”
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Validating a New Oscillometric Device for Aortic Pulse Wave Velocity Measurements in Children and Adolescents by Kracht, Daniela, Shroff, Rukshana, Baig, Sabrina, Doyon, Anke, Jacobi, Christoph, Zeller, Rene, Querfeld, Uwe, Schaefer, Franz, Wühl, Elke, Schmidt, Bernhard M.W., Melk, Anette

“…Background Pulse wave velocity (PWV) is an indicator of aortic stiffness and a predictor of cardiovascular risk. Applanation tonometry (e.g., SphygmoCor) is a…”
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Reduced Microvascular Density in Omental Biopsies of Children with Chronic Kidney Disease by Burkhardt, Dorothea, Bartosova, Maria, Schaefer, Betti, Grabe, Niels, Lahrmann, Bernd, Nasser, Hamoud, Freise, Christian, Schneider, Axel, Lingnau, Anja, Degenhardt, Petra, Ranchin, Bruno, Sallay, Peter, Cerkauskiene, Rimante, Malina, Michal, Ariceta, Gema, Schmitt, Claus Peter, Querfeld, Uwe

“…Endothelial dysfunction is an early manifestation of cardiovascular disease (CVD) and consistently observed in patients with chronic kidney disease (CKD). We…”
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Differential Effects of 25-Hydroxyvitamin D3 versus 1α 25-Dihydroxyvitamin D3 on Adipose Tissue Browning in CKD-Associated Cachexia by Mak, Robert H., Querfeld, Uwe, Gonzalez, Alex, Gunta, Sujana, Cheung, Wai W.

“…Patients with chronic kidney disease (CKD) often have low serum concentrations of 25(OH)D3 and 1,25(OH)2D3. We investigated the differential effects of…”
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Markers of bone metabolism are affected by renal function and growth hormone therapy in children with chronic kidney disease by Doyon, Anke, Fischer, Dagmar-Christiane, Bayazit, Aysun Karabay, Canpolat, Nur, Duzova, Ali, Sözeri, Betül, Bacchetta, Justine, Balat, Ayse, Büscher, Anja, Candan, Cengiz, Cakar, Nilgun, Donmez, Osman, Dusek, Jiri, Heckel, Martina, Klaus, Günter, Mir, Sevgi, Özcelik, Gül, Sever, Lale, Shroff, Rukshana, Vidal, Enrico, Wühl, Elke, Gondan, Matthias, Melk, Anette, Querfeld, Uwe, Haffner, Dieter, Schaefer, Franz

“…The extent and relevance of altered bone metabolism for statural growth in children with chronic kidney disease is controversial. We analyzed the impact of…”
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Protective effects of the polyphenols (+)-episesamin and sesamin against PDGF-BB-induced activation of vascular smooth muscle cells are mediated by induction of haem oxygenase-1 and inhibition of mitogenic signalling by Freise, Christian, Sommer, Kerstin, Querfeld, Uwe

“…•The polyphenols (+)-episesamin and sesamin block PDGF-BB-induced activation of VSMC.•Targets are PDGF-induced MAPK and PI3K signalling and the activation of…”
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A Hospital-Based Intermittent Nocturnal Hemodialysis Program for Children and Adolescents by Hoppe, Anne, von Puttkamer, Christina, RN, Linke, Ursula, RN, Kahler, Cindy, RN, Booß, Martina, RN, Braunauer-Kolberg, Renate, RN, Hofmann, Katja, RN, Joachimsky, Petra, RN, Hirte, Ingrid, Schley, Sylke, Utsch, Boris, MD, Thumfart, Julia, MD, Briese, Sonia, MD, Gellermann, Jutta, MD, Zimmering, Miriam, MD, Querfeld, Uwe, MD, Müller, Dominik, MD

“…Objective To establish a hospital-based nocturnal hemodialysis (NHD) program for children and adolescents. Study design Sixteen patients (age, 0.5 to 17 years)…”
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Determinants of Statural Growth in European Children With Chronic Kidney Disease: Findings From the Cardiovascular Comorbidity in Children With Chronic Kidney Disease (4C) Study by Behnisch, Rouven, Kirchner, Marietta, Anarat, Ali, Bacchetta, Justine, Shroff, Rukshana, Bilginer, Yelda, Mir, Sevgi, Caliskan, Salim, Paripovic, Dusan, Harambat, Jerome, Mencarelli, Francesca, Büscher, Rainer, Arbeiter, Klaus, Soylemezoglu, Oguz, Zaloszyc, Ariane, Zurowska, Aleksandra, Melk, Anette, Querfeld, Uwe, Schaefer, Franz

“…Failure of statural growth is one of the major long-term sequelae of chronic kidney disease (CKD) in children. In recent years effective therapeutic strategies…”
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Arterial stiffness in children after renal transplantation by Briese, Sonia, Claus, Maren, Querfeld, Uwe

“…Long-term survival after successful transplantation is limited by cardiovascular disease. We studied changes in arterial function in children after renal…”
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CTLA4 Polymorphisms in Minimal Change Nephrotic Syndrome in Children: A Case-Control Study by Ohl, Kim, PhD, Eberhardt, Christiane, MD, Spink, Clemens, MD, Zahn, Katharina, MD, Wagner, Norbert, MD, Eggermann, Thomas, MD, Kemper, Markus J., MD, Querfeld, Uwe, MD, Hoppe, Bernd, MD, Harendza, Sigrid, MD, Tenbrock, Klaus, MD

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