Search Results - "Quelle, DE"

Racismo Algorítmico e cultura digital: um olhar a partir da Inteligência artificial (IA) by Santos de Queiroz, Lilian Quelle, Soares de Lima Júnior, Arnaud

“…Este trabalho apresenta-se como um ensaio teórico que aborda as relações entre racismo algorítmico e inteligência artificial no âmbito da cultura digital. Como…”
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Nucleophosmin (B23) Targets ARF to Nucleoli and Inhibits Its Function by Korgaonkar, Chandrashekhar, Hagen, Jussara, Tompkins, Van, Frazier, April A., Allamargot, Chantal, Quelle, Frederick W., Quelle, Dawn E.

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Tumor Suppression at the Mouse INK4a Locus Mediated by the Alternative Reading Frame Product p19 by Kamijo, Takehiko, Zindy, Frederique, Roussel, Martine F., Quelle, Dawn E., Downing, James R., Ashmun, Richard A., Grosveld, Gerard, Sherr, Charles J.

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Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest by Ouelle, Dawn E., Zindy, Frédérique, Ashmun, Richard A., Sherr, Charles J.

“…The INK4a ( MTS1, CDKN2) gene encodes an inhibitor (p16 INK4a) of the cyclin D-dependent kinases CDK4 and CDK6 that blocks them from phosphorylating the…”
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The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia by Linggi, Bryan, Müller-Tidow, Carsten, van de Locht, Louis, Hu, Ming, Nip, John, Serve, Hubert, Berdel, Wolfgang E, van der Reijden, Bert, Quelle, Dawn E, Rowley, Janet D, Cleveland, John, Jansen, Joop H, Pandolfi, Pier Paolo, Hiebert, Scott W

“…The t(8;21) is one of the most frequent chromosomal translocations associated with acute leukemia. This translocation creates a fusion protein consisting of…”
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ARF Function Does Not Require p53 Stabilization or Mdm2 Relocalization by Korgaonkar, Chandrashekhar, Zhao, Lili, Modestou, Modestos, Quelle, Dawn E.

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Cyclin G1 has growth inhibitory activity linked to the ARF-Mdm2-p53 and pRb tumor suppressor pathways by ZHAO, Lili, SAMUELS, Tina, WINCKLER, Sarah, KORGAONKAR, Chandrashekhar, TOMPKINS, Van, HOME, Mary C, QUELLE, Dawn E

“…Cyclin G1 is a p53-responsive gene that is induced in alternative reading frame (ARF)-arrested cells, yet its role in growth control is unclear. We tested its…”
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D-type cyclin-dependent kinase activity in mammalian cells by MATSUSHIME, H, QUELLE, D. E, SHURTLEFF, S. A, SHIBUYA, M, SHERR, C. J, KATO, J.-Y

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Dna damage-induced G(1) arrest in hematopoietic cells is overridden following phosphatidylinositol 3-kinase-dependent activation of cyclin-dependent kinase 2 by Eapen, A K, Henry, M K, Quelle, D E, Quelle, F W

“…Exposure of hematopoietic cells to DNA-damaging agents induces p53-independent cell cycle arrest at a G(1) checkpoint. Previously, we have shown that this…”
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The alternative reading frame tumor suppressor inhibits growth through p21-dependent and p21-independent pathways by MODESTOU, Modestos, PUIG-ANTICH, Valerie, KORGAONKAR, Chandrashekhar, EAPEN, Alex, QUELLE, Dawn E

“…The alternative reading frame (ARF) tumor suppressor mediates growth arrest or apoptosis through activation of the p53 tumor suppressor. A prevailing concept…”
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DNA Damage-Induced G sub(1) Arrest in Hematopoietic Cells Is Overridden following Phosphatidylinositol 3-Kinase-Dependent Activation of Cyclin-Dependent Kinase 2 by Eapen, A K, Henry, M K, Quelle, DE, Quelle, F W

“…Exposure of hematopoietic cells to DNA-damaging agents induces p53-independent cell cycle arrest at a G sub(1) checkpoint. Previously, we have shown that this…”
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Generation and characterization of monoclonal antibodies to NIAM: a nuclear interactor of ARF and Mdm2 by Hagen, Jussara, Tompkins, Van, Dudakovic, Amel, Weydert, Jamie A, Quelle, Dawn E

“…Nuclear interactor of ARF and Mdm2 (NIAM) is a newly discovered growth inhibitor that helps maintain chromosomal stability. It is functionally linked to the…”
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The t(8; 21) fusion protein, AML1-ETO, specifically represses the transcription of the p14 super(ARF) tumor suppressor in acute myeloid leukemia by Linggi, B, Mueller-Tidow, C, Van De Locht, L, Hu, Ming, Nip, J, Serve, H, Berdel, W E, Van Der Reijden, B, Quelle, DE, Rowley, J D, Cleveland, J, Jansen, J H, Pandolfi, P P, Hiebert, S W

“…The t(8; 21) is one of the most frequent chromosomal translocations associated with acute leukemia. This translocation creates a fusion protein consisting of…”
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Localized cytosolic domains of the erythropoietin receptor regulate growth signaling and down-modulate responsiveness to granulocyte-macrophage colony-stimulating factor by QUELLE, D. E, WOJCHOWSKI, D. M

“…Erythrocyte development in mammals depends in part upon the interaction of the glycopeptide hormone erythropoietin (EPO) with cell surface receptors on…”
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Mutations in the WSAWSE and cytosolic domains of the erythropoietin receptor affect signal transduction and ligand binding and internalization by QUELLE, D. E, QUELLE, F. W, WOJCHOWSKI, D. M

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Expression of the p16 super(INK4a) tumor suppressor versus other INK4 family members during mouse development and aging by Zindy, F, Quelle, DE, Roussel, M F, Sherr, C J

“…Four INK4 proteins can prevent cell proliferation by specifically inhibiting cyclin D-dependent kinases. Both p18 super(INK4c) and p19 super(INK4d) were widely…”
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Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16 super(INK4a) but not by the alternative reading frame protein p19 super(ARF) by Quelle, DE, Cheng, Mangeng, Ashmun, R A, Sherr, C J

“…The INK4a gene, one of the most frequently disrupted tumor suppressor loci in human cancer, encodes two unrelated proteins, p16 super(INK4a) and p19…”
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The extended box 2 subdomain of erythropoietin receptor is nonessential for Jak2 activation yet critical for efficient mitogenesis in FDC-ER cells by He, T C, Jiang, N, Zhuang, H, Quelle, D E, Wojchowski, D M

“…The development of erythroid progenitor cells depends upon exposure to the glycoprotein hormone, erythropoietin (EPO). Binding of EPO to its transmembrane…”
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Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19 super(ARF) by Kamijo, T, Zindy, F, Roussel, M F, Quelle, DE, Downing, J R, Ashmun, R A, Grosveld, G, Sherr, C J

“…The INK4a tumor suppressor locus encodes p16 super(INK4a), an inhibitor of cyclin D-dependent kinases, and p19 super(ARF), an alternative reading frame protein…”
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Interleukin 3, granulocyte-macrophage colony-stimulating factor, and transfected erythropoietin receptors mediate tyrosine phosphorylation of a common cytosolic protein (pp100) in FDC-ER cells by Quelle, F W, Quelle, D E, Wojchowski, D M

“…Receptors for the hematopoietic growth factors erythropoietin, interleukin 3 (IL-3), and granulocyte-macrophage colony-stimulating factor (GM-CSF) are members…”
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