Search Results - "Queiroz, Maria João R.P."

A comparative study of chemical composition, antioxidant and antimicrobial properties of Morchella esculenta (L.) Pers. from Portugal and Serbia by Heleno, Sandrina A., Stojković, Dejan, Barros, Lillian, Glamočlija, Jasmina, Soković, Marina, Martins, Anabela, Queiroz, Maria João R.P., Ferreira, Isabel C.F.R.

“…A comparative study on chemical composition (nutritional value, primary and secondary metabolites), antioxidant properties (scavenging activity, reducing power…”
Get full text

Solid and aqueous magnetoliposomes as nanocarriers for a new potential drug active against breast cancer by Rodrigues, Ana Rita O., Mendes, Pedro M.F., Silva, Pedro M.L., Machado, V.A., Almeida, Bernardo G., Araújo, J.P., Queiroz, Maria-João R.P., Castanheira, Elisabete M.S., Coutinho, Paulo J.G.

“…[Display omitted] •Superparamagnetic magnetite nanoparticles with 12nm size were synthesized.•Aqueous and solid magnetoliposomes, with sizes below 150nm, were…”
Get full text

Bioactivity of phenolic acids: Metabolites versus parent compounds: A review by Heleno, Sandrina A., Martins, Anabela, Queiroz, Maria João R.P., Ferreira, Isabel C.F.R.

“…•Phenolic acids are representative molecules in the diet.•After absorption, they are extensively metabolized in the organism.•Glucuronidation, methylation and…”
Get full text

Efficient synthesis of 6-(hetero)arylthieno[3,2- b]pyridines by Suzuki–Miyaura coupling. Evaluation of growth inhibition on human tumor cell lines, SARs and effects on the cell cycle by Queiroz, Maria-João R.P., Calhelha, Ricardo C., Vale-Silva, Luís A., Pinto, Eugénia, Lima, Raquel T., Vasconcelos, M. Helena

“…A wide variety of new bi(hetero)aryl derivatives of the thieno[3,2- b]pyridine skeleton was obtained in high to excellent yields (65–91%) by Suzuki–Miyaura…”
Get full text

New potential antitumoral di(hetero)arylether derivatives in the thieno[3,2-b]pyridine series: Synthesis and fluorescence studies in solution and in nanoliposomes by Queiroz, Maria-João R.P., Dias, Sofia, Peixoto, Daniela, Rodrigues, Ana Rita O., Oliveira, Andreia D.S., Coutinho, Paulo J.G., Vale-Silva, Luís A., Pinto, Eugénia, Castanheira, Elisabete M.S.

“…► Synthesis of new di(hetero)arylethers in the thieno[3,2-b]pyridine series by copper catalyzed CO coupling using an amino acid as ligand. ► Evaluation of…”
Get full text

Evaluation of the antioxidant properties of diarylamines in the benzo[ b]thiophene series by free radical scavenging activity and reducing power by Ferreira, Isabel C.F.R., Queiroz, Maria-João R.P., Vilas-Boas, Miguel, Estevinho, Letı́cia M., Begouin, Agathe, Kirsch, Gilbert

“…Chemical assays for the determination of the reducing power and free radical scavenging activity of the diarylamines are presented. The antioxidant properties…”
Get full text

Application of PEG400 in the one-pot synthesis of 7-[4-alkyl- or (hetero)aryl-1H-1,2,3-triazol-1-yl]thieno[3,2-b]pyridines via SNAr and Cu(I)-Catalyzed Azide-Alkyne Cycloaddition and preliminary evaluation of their anti-tumour activity by Rodrigues, Juliana M., Calhelha, Ricardo C., Ferreira, Isabel C.F.R., Queiroz, Maria-João R.P.

“…[Display omitted] •Synthesis of 7-[4-alkyl- or (hetero)aryl-1H-1,2,3-triazol-1-yl]thieno[3,2-b]pyridines.•One-pot procedure from 7-chlorothieno[3,2-b]pyridine…”
Get full text

Palladium-catalyzed amination and cyclization to heteroannellated indoles and carbazoles by Ferreira, Isabel C.F.R, Queiroz, Maria-João R.P, Kirsch, Gilbert

“…New ortho-bromodiarylamines in the benzo[ b]thiophene series were prepared by palladium-catalyzed amination, either in the benzene or in the thiophene ring…”
Get full text

Synthesis, antiangiogenesis evaluation and molecular docking studies of 1-aryl-3-[(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas: Discovery of a new substitution pattern for type II VEGFR-2 Tyr kinase inhibitors by Machado, Vera A., Peixoto, Daniela, Costa, Raquel, Froufe, Hugo J.C., Calhelha, Ricardo C., Abreu, Rui M.V., Ferreira, Isabel C.F.R., Soares, Raquel, Queiroz, Maria-João R.P.

“…[Display omitted] The synthesis and biological evaluation of novel 1-aryl-3-[2-, 3- or 4-(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas 3, 4 and 5 as VEGFR-2…”
Get full text

Antimicrobial and demelanizing activity of Ganoderma lucidum extract, p-hydroxybenzoic and cinnamic acids and their synthetic acetylated glucuronide methyl esters by Heleno, Sandrina A., Ferreira, Isabel C.F.R., Esteves, Ana P., Ćirić, Ana, Glamočlija, Jasmina, Martins, Anabela, Soković, Marina, Queiroz, Maria João R.P.

“…•Protected glucuronide derivatives of p-hydroxybenzoic and cinnamic acids were synthesized.•The compounds revealed higher antimicrobial activity than…”
Get full text

Synthesis of novel 8-(het)aryl-6H-pyrano[4′,3′:4,5]thieno[3,2-b]pyridines by 6-endo-dig cyclization of Sonogashira products and halolactonizations with Cu salts/NXS. Preliminary antitumor evaluation by Rodrigues, Juliana M., Buisson, Pierre, Pereira, Joana M., Pinheiro, Inês M., Fernández-Marcelo, Tamara, Vasconcelos, M. Helena, Berteina-Raboin, Sabine, Queiroz, Maria-João R.P.

“…Novel 8-(het)aryl-6H-pyrano[4′,3′:4,5]thieno[3,2-b]pyridines were prepared in good to high yields by a tandem one-pot procedure of Sonogashira coupling and…”
Get full text

Fruiting body, spores and in vitro produced mycelium of Ganoderma lucidum from Northeast Portugal: A comparative study of the antioxidant potential of phenolic and polysaccharidic extracts by Heleno, Sandrina A., Barros, Lillian, Martins, Anabela, Queiroz, Maria João R.P., Santos-Buelga, Celestino, Ferreira, Isabel C.F.R.

“…Ganoderma lucidum is one of the most extensively studied mushrooms due to its medicinal properties. Herein, a systematic study was carried out in order to…”
Get full text

Anti-hepatocellular carcinoma activity using human HepG2 cells and hepatotoxicity of 6-substituted methyl 3-aminothieno[3,2- b]pyridine-2-carboxylate derivatives: In vitro evaluation, cell cycle analysis and QSAR studies by Abreu, Rui M.V., Ferreira, Isabel C.F.R., Calhelha, Ricardo C., Lima, Raquel T., Vasconcelos, M. Helena, Adega, Filomena, Chaves, Raquel, Queiroz, Maria-João R.P.

“…Hepatocellular carcinoma (HCC) is a highly complex cancer, resistant to commonly used treatments and new therapeutic agents are urgently needed. A total of…”
Get full text

Novel synthetic routes to thienocarbazoles via palladium or copper catalyzed amination or amidation of arylhalides and intramolecular cyclization by Ferreira, Isabel C.F.R, Queiroz, Maria-João R.P, Kirsch, Gilbert

“…Palladium or copper catalyzed aminations or amidations were performed to obtain diarylamines and diarylacetamides precursors of thienocarbazoles. The fact that…”
Get full text

Nutritional value, bioactive compounds and antioxidant properties of three edible mushrooms from Poland by Heleno, Sandrina A., Ferreira, Raíssa Carolina, Antonio, Amilcar L., Queiroz, Maria-João R.P., Barros, Lillian, Ferreira, Isabel C.F.R.

Get full text

Infusion and decoction of wild German chamomile: Bioactivity and characterization of organic acids and phenolic compounds by Guimarães, Rafaela, Barros, Lillian, Dueñas, Montserrat, Calhelha, Ricardo C., Carvalho, Ana Maria, Santos-Buelga, Celestino, Queiroz, Maria João R.P., Ferreira, Isabel C.F.R.

“…► Matricaria recutita methanolic extract and infusion gave antitumour potential. ► They were selective to colon and cervical carcinoma cell lines, without…”
Get full text

Phenolic, Polysaccharidic, and Lipidic Fractions of Mushrooms from Northeastern Portugal: Chemical Compounds with Antioxidant Properties by Heleno, Sandrina A, Barros, Lillian, Martins, Anabela, Queiroz, Maria João R. P, Santos-Buelga, Celestino, Ferreira, Isabel C. F. R

“…Mushrooms do not constitute a significant portion of the human diet, but their consumption continues to increase due to their functional benefits and presence…”
Get full text

Induction of apoptosis by photoexcited tetracyclic compounds derivatives of benzo[ b]thiophenes and pyridines by Viola, Giampietro, Salvador, Alessia, Vedaldi, Daniela, Fortunato, Elena, Disarò, Silvia, Basso, Giuseppe, Queiroz, Maria-João R.P.

“…The antiproliferative activity, upon UVA irradiation, of two tetracyclic derivatives of benzo[ b]thiophenes and pyridines, a benzo[ b]thienopyridopyrimidone (…”
Get full text

Novel dehydropeptide-based magnetogels containing manganese ferrite nanoparticles as antitumor drug nanocarriers by Veloso, Sérgio R S, Magalhães, Carlos A B, Rodrigues, Ana Rita O, Vilaça, H, Queiroz, Maria-João R P, Martins, J A, Coutinho, Paulo J G, Ferreira, Paula M T, Castanheira, Elisabete M S

“…Herein, novel dehydropeptide-based magnetogels, based on the hydrogelators Npx-l-Phe-Z-ΔAbu-OH, Npx-l-Trp-Z-ΔPhe-OH and…”
Get more information

The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds by Barros, Lillian, Calhelha, Ricardo C., Queiroz, Maria João R.P., Santos-Buelga, Celestino, Santos, Elândia A., Regis, Wiliam C.B., Ferreira, Isabel C.F.R.

“…•Açaí seeds revealed high antioxidant and cytotoxic activity against tumor cell lines.•HeLa (cervical carcinoma) was the most susceptible human tumor cell…”
Get full text