Search Results - "Quashie, Neils"

Seasonal variations in Plasmodium falciparum parasite prevalence assessed by varying diagnostic tests in asymptomatic children in southern Ghana by Ayanful-Torgby, Ruth, Quashie, Neils B, Boampong, Johnson N, Williamson, Kim C, Amoah, Linda E

“…Plasmodium falciparum infections presenting either as symptomatic or asymptomatic may contain sexual stage parasites (gametocytes) that are crucial to malaria…”
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Treatment of COVID-19 with Chloroquine: Implication for Malaria Chemotherapy Using ACTs in Disease Endemic Countries by Quashie, Neils Ben, Duah-Quashie, Nancy Odurowah

“…Abstract Based on reports of parasite resistance and on World Health Organization recommendation, chloroquine was replaced with the artemisinin-based…”
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Plasmodium falciparum Kelch Propeller Polymorphisms in Clinical Isolates from Ghana from 2007 to 2016 by Matrevi, Sena A, Opoku-Agyeman, Philip, Quashie, Neils B, Bruku, Selassie, Abuaku, Benjamin, Koram, Kwadwo A, Fox, Anne, Letizia, Andrew, Duah-Quashie, Nancy O

“…The continuous surveillance of polymorphisms in the kelch propeller domain of from Africa is important for the discovery of the actual markers of artemisinin…”
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Plasmodium falciparum merozoite invasion ligands, linked antimalarial resistance loci and ex vivo responses to antimalarials in The Gambia by Mbye, Haddijatou, Mane, Karim, Diop, Mouhamadou Fadel, Demba, Martha Anita, Bojang, Fatoumata, Mohammed, Nuredin Ibrahim, Jeffries, David, Quashie, Neils Ben, D'Alessandro, Umberto, Amambua-Ngwa, Alfred

“…Artemether/lumefantrine is the most commonly used artemisinin-based combination treatment (ACT) for malaria in sub-Saharan Africa. Drug resistance to ACT…”
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Malaria artemisinin resistance: an extracellular vesicles export hypothesis by Tandoh, Kwesi Z., Morang'a, Collins M., Wilson, Michael, Quashie, Neils B., Duah-Quashie, Nancy O.

“…Plasmodium falciparum causes malaria, and its resistance to artemisinin (ART) – a drug used for managing malaria – threatens to interfere with the effective…”
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Assessing the Roles of Molecular Markers of Antimalarial Drug Resistance and the Host Pharmacogenetics in Drug-Resistant Malaria by Hodoameda, Peter, Duah-Quashie, Nancy Odurowah, Quashie, Neils Ben

“…Malaria caused by the Plasmodium parasites is a major public health concern in malaria-endemic regions with P. falciparum causing the most severe form of the…”
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Estimation of parasite age and synchrony status in Plasmodium falciparum infections by Ciuffreda, Laura, Zoiku, Felix Kwame, Quashie, Neils B., Ranford-Cartwright, Lisa C.

“…Human malaria parasites have complex but poorly understood population dynamics inside their human host. In some but not all infections, parasites progress…”
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Implicating extracellular vesicles in Plasmodium falciparum artemisinin resistance development by Tandoh, Kwesi Z., Wilson, Michael D., Quashie, Neils B., Duah‐Quashie, Nancy O.

“…Plasmodium falciparum malaria remains a disease of significant public health impact today. With the risk of emerging artemisinin resistance stalling malaria…”
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Novel pfk13 polymorphisms in Plasmodium falciparum population in Ghana by Matrevi, Sena Adzoa, Tandoh, Kwesi Zandoh, Bruku, Selassie, Opoku-Agyeman, Philip, Adams, Tryphena, Ennuson, Nana Aba, Asare, Bright, Hagan, Oheneba Charles Kofi, Abuaku, Benjamin, Koram, Kwadwo Ansah, Fox, Ann, Quashie, Neils Ben, Letizia, Andrew G., Duah-Quashie, Nancy Odurowah

“…The molecular determinants of Plasmodium falciparum artemisinin resistance are the single nucleotide polymorphisms in the parasite’s kelch propeller domain,…”
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Comprehensive characterization of purine and pyrimidine transport activities in Trichomonas vaginalis and functional cloning of a trichomonad nucleoside transporter by Natto, Manal J., Miyamoto, Yukiko, Munday, Jane C., AlSiari, Tahani A., Al‐Salabi, Mohammed I., Quashie, Neils B., Eze, Anthonius A., Eckmann, Lars, De Koning, Harry P.

“…Trichomoniasis is a common and widespread sexually‐transmitted infection, caused by the protozoan parasite Trichomonas vaginalis. T. vaginalis lacks the…”
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High Prevalence of Molecular Markers of Plasmodium falciparum Resistance to Sulphadoxine–Pyrimethamine in Parts of Ghana: A Threat to ITPTp-SP? by Afutu, Leslie L, Boampong, Johnson N, Quashie, Neils B

“…Abstract   Malaria in pregnancy is a huge public health problem as it is the cause of maternal anaemia, still birth, premature delivery, low birth weight among…”
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Amplification of GTP-cyclohydrolase 1 gene in Plasmodium falciparum isolates with the quadruple mutant of dihydrofolate reductase and dihydropteroate synthase genes in Ghana by Osei, Musah, Ansah, Felix, Matrevi, Sena A, Asante, Kwaku P, Awandare, Gordon A, Quashie, Neils B, Duah, Nancy O

“…Sulfadoxine-pyrimethamine (SP) is used as malaria chemoprophylaxis for pregnant women and children in Ghana. Plasmodium falciparum resistance to SP is linked…”
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In vivo efficacy of top five surveyed Ghanaian herbal anti-malarial products by Wilmot, Dennis, Ameyaw, Elvis Ofori, Amoako-Sakyi, Daniel, Boampong, Johnson Nyarko, Quashie, Neils Ben

“…Anti-malarial herbal preparations (HPs) continue to enjoy high patronage in Ghana despite reports that the artemisinin-based combination therapy (ACT), the…”
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Transcriptome-module phenotype association study implicates extracellular vesicles biogenesis in Plasmodium falciparum artemisinin resistance by Tandoh, Kwesi Z., Hagan, Oheneba C., Wilson, Michael D., Quashie, Neils B., Duah-Quashie, Nancy O.

“…Plasmodium falciparum malaria is still an important disease in sub-Saharan Africa (sSA). Great strides have been made in its control spear-headed by…”
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Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine combinations for uncomplicated malaria in 10 sentinel sites across Ghana: 2015-2017 by Abuaku, Benjamin, Duah-Quashie, Nancy O, Quaye, Lydia, Matrevi, Sena A, Quashie, Neils, Gyasi, Akosua, Owusu-Antwi, Felicia, Malm, Keziah, Koram, Kwadwo

“…Routine surveillance on the therapeutic efficacy of artemisinin-based combination therapy (ACT) has been ongoing in Ghana since 2005. The sixth round of…”
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Increased pfmdr1 gene copy number and the decline in pfcrt and pfmdr1 resistance alleles in Ghanaian Plasmodium falciparum isolates after the change of anti-malarial drug treatment policy by Duah, Nancy O, Matrevi, Sena A, de Souza, Dziedzom K, Binnah, Daniel D, Tamakloe, Mary M, Opoku, Vera S, Onwona, Christiana O, Narh, Charles A, Quashie, Neils B, Abuaku, Benjamin, Duplessis, Christopher, Kronmann, Karl C, Koram, Kwadwo A

“…With the introduction of artemisinin-based combination therapy (ACT) in 2005, monitoring of anti-malarial drug efficacy, which includes the use of molecular…”
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Prevalence of Plasmodium falciparum delayed clearance associated polymorphisms in adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1) genes in Ghanaian isolates by Adams, Tryphena, Ennuson, Nana Aba A, Quashie, Neils B, Futagbi, Godfred, Matrevi, Sena, Hagan, Oheneba C K, Abuaku, Benjamin, Koram, Kwadwo A, Duah, Nancy O

“…Plasmodium falciparum delayed clearance with the use of artemisinin-based combination therapy (ACTs) has been reported in some African countries. Single…”
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Genetic diversity of Plasmodium falciparum isolates from uncomplicated malaria cases in Ghana over a decade by Duah, Nancy O, Matrevi, Sena A, Quashie, Neils B, Abuaku, Benjamin, Koram, Kwadwo A

“…Genotyping malaria parasites to assess their diversity in different geographic settings have become necessary for the selection of antigenic epitopes for…”
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Trends and predictive factors for treatment failure following artemisinin-based combination therapy among children with uncomplicated malaria in Ghana: 2005-2018 by Abuaku, Benjamin, Duah-Quashie, Nancy Odurowah, Quashie, Neils, Gyasi, Akosua, Afriyie, Patricia Opoku, Owusu-Antwi, Felicia, Ghansah, Anita, Malm, Keziah Laurencia, Bart-Plange, Constance, Koram, Kwadwo Ansah

“…Since the introduction of artemisinin-based combination therapy (ACT) in Ghana in 2005 there has been a surveillance system by the National Malaria Control…”
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An improved SYBR Green-1-based fluorescence method for the routine monitoring of Plasmodium falciparum resistance to anti-malarial drugs by Dery, Victor, Duah, Nancy O, Ayanful-Torgby, Ruth, Matrevi, Sena A, Anto, Francis, Quashie, Neils B

“…The recently introduced SYBR Green1 (SG) assay for testing parasites susceptibility to anti-malarial drugs needs further improvement. This has been…”
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