Search Results - "Quan, Xianglan"

miR-590-5p/Tiam1-mediated glucose metabolism promotes malignant evolution of pancreatic cancer by regulating SLC2A3 stability by Liu, Ying, Jin, Aihua, Quan, Xianglan, Shen, Xionghu, Zhou, Houkun, Zhao, Xingyu, Lin, Zhenhua

“…Abstract Background T lymphoma invasion and metastasis 1 (Tiam1) is a tumor related gene that specifically activates Rho-like GTPases Rac1 and plays a critical…”
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Essential Role of Mitochondrial Ca2+ Uniporter in the Generation of Mitochondrial pH Gradient and Metabolism-Secretion Coupling in Insulin-releasing Cells by Quan, Xianglan, Nguyen, Tuyet Thi, Choi, Seong-Kyung, Xu, Shanhua, Das, Ranjan, Cha, Seung-Kuy, Kim, Nari, Han, Jin, Wiederkehr, Andreas, Wollheim, Claes B., Park, Kyu-Sang

“…In pancreatic β-cells, ATP acts as a signaling molecule initiating plasma membrane electrical activity linked to Ca2+ influx, which triggers insulin…”
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Transforming Growth Factor β1-induced Apoptosis in Podocytes via the Extracellular Signal-regulated Kinase-Mammalian Target of Rapamycin Complex 1-NADPH Oxidase 4 Axis by Das, Ranjan, Xu, Shanhua, Nguyen, Tuyet Thi, Quan, Xianglan, Choi, Seong-Kyung, Kim, Soo-Jin, Lee, Eun Young, Cha, Seung-Kuy, Park, Kyu-Sang

“…TGF-β is a pleiotropic cytokine that accumulates during kidney injuries, resulting in various renal diseases. We have reported previously that TGF-β1 induces…”
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Mitochondrial oxidative stress mediates high-phosphate-induced secretory defects and apoptosis in insulin-secreting cells by Nguyen, Tuyet Thi, Quan, Xianglan, Hwang, Kyu-Hee, Xu, Shanhua, Das, Ranjan, Choi, Seong-Kyung, Wiederkehr, Andreas, Wollheim, Claes B, Cha, Seung-Kuy, Park, Kyu-Sang

“…Inorganic phosphate (Pi) plays an important role in cell signaling and energy metabolism. In insulin-releasing cells, Pi transport into mitochondria is…”
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The Metabolomic Characterization of Different Types of Coronary Atherosclerotic Heart Disease in Male by Fan, Yuxuan, Quan, Xianglan, Liu, Shengquan, Yue, Le, Jiang, Jizong, Fan, Zhiqing

“…Background. In clinical practice, many patients with coronary atherosclerotic heart disease (CAD) have atypical clinical symptoms. It is difficult to…”
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Autocrine insulin increases plasma membrane KATP channel via PI3K-VAMP2 pathway in MIN6 cells by Xu, Shanhua, Kim, Ji-Hee, Hwang, Kyu-Hee, Das, Ranjan, Quan, Xianglan, Nguyen, Tuyet Thi, Kim, Soo-Jin, Cha, Seung-Kuy, Park, Kyu-Sang

“…Regulation of ATP-sensitive inwardly rectifying potassium (KATP) channel plays a critical role in metabolism-secretion coupling of pancreatic β-cells. Released…”
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High-dose clevudine impairs mitochondrial function and glucose-stimulated insulin secretion in INS-1E cells by Jang, Yoon-Ok, Quan, Xianglan, Das, Ranjan, Xu, Shanhua, Chung, Choon-Hee, Ahn, Chan Mug, Baik, Soon-Koo, Kong, In Deok, Park, Kyu-Sang, Kim, Moon Young

“…Clevudine is a nucleoside analog reverse transcriptase inhibitor that exhibits potent antiviral activity against hepatitis B virus (HBV) without serious side…”
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Oncolytic Adenovirus RCA-TERT-Ad35 Carrying Human Telomerase Reverse Transcriptase Promoter Targets Breast Cancer Stem Cells by Wang, Weichuan, Chen, Lulu, Quan, Xianglan, Li, Ying, Jin, Yongmin, Jin, Wenbiao, Yu, Kexin, Zhang, Songnan

“…Objective To investigate the role of oncolytic adenovirus RCA-TERT-Ad35 carrying human telomerase reverse transcriptase promoter in targeting breast cancer…”
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Mitochondrial calcium uniporter in Drosophila transfers calcium between the endoplasmic reticulum and mitochondria in oxidative stress-induced cell death by Choi, Sekyu, Quan, Xianglan, Bang, Sunhoe, Yoo, Heesuk, Kim, Jiyoung, Park, Jiwon, Park, Kyu-Sang, Chung, Jongkyeong

“…Mitochondrial calcium plays critical roles in diverse cellular processes ranging from energy metabolism to cell death. Previous studies have demonstrated that…”
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Camrelizumab Combined with Apatinib for Portal Vein Tumor Thrombus in Advanced Hepatocellular Carcinoma: Two Case Reports by Chen, Ning, Zhang, Lei, Gao, Aimei, Piao, Longzhen, Quan, Xianglan, Shen, Xionghu

“…Portal vein tumor thrombus (PVTT) is a common complication of primary hepatocellular carcinoma (HCC). HCC typically infiltrates intrahepatic vessels,…”
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Upregulation of mitochondrial Nox4 mediates TGF-β-induced apoptosis in cultured mouse podocytes by Das, Ranjan, Xu, Shanhua, Quan, Xianglan, Nguyen, Tuyet Thi, Kong, In Deok, Chung, Choon Hee, Lee, Eun Young, Cha, Seung-Kuy, Park, Kyu-Sang

“…Injury to podocytes leads to the onset of chronic renal diseases characterized by proteinuria. Elevated transforming growth factor (TGF)-β in kidney tissue is…”
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PIAS3/SOCS1-STAT3 axis responses to oxidative stress in hepatocellular cancer cells by Sun, Honghua, Li, Yanglong, Quan, Xianglan, Chen, Ning, Jin, Xinglin, Jin, Wenbiao, Jin, Yongmin, Shen, Xionghu

“…The participation of STAT3 and its upstream inhibitors, PIAS3 and SOCS1, in the oxidative response of hepatocellular carcinoma (HCC) cells was uncertain. Here,…”
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Long non-coding RNA activated by TGF-β expression in cancer prognosis: A meta-analysis by Shen, Xionghu, Piao, Longzhen, Zhang, Songnan, Cui, Yan, Cui, Yuzhen, Quan, Xianglan, Sun, Honghua

“…Recently, long non-coding RNA activated by transforming growth factor beta (TGF-β) (lncRNA ATB) was shown to be useful in cancer prognosis, however, its…”
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Intracellular alkalinization by phosphate uptake via type III sodium–phosphate cotransporter participates in high‐phosphate‐induced mitochondrial oxidative stress and defective insulin secretion by Nguyen, Tuyet Thi, Quan, Xianglan, Xu, Shanhua, Das, Ranjan, Cha, Seung‐Kuy, Kong, Deok, Shong, Minho, Wollheim, Claes B., Park, Kyu‐Sang

“…ABSTRACT Elevated plasma levels of inorganic phosphate (Pi) are harmful, causing, among other complications, vascular calcification anddefective insulin…”
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Mitochondrial phosphate transport during nutrient stimulation of INS-1E insulinoma cells by Quan, Xianglan, Das, Ranjan, Xu, Shanhua, Cline, Gary W., Wiederkehr, Andreas, Wollheim, Claes B., Park, Kyu-Sang

“…•Pi induces mitochondrial hyperpolarisation.•Pi increases mitochondrial ATP export.•Pi-induced activation depends on mitochondrial pH gradient.•Knockdown of…”
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Autocrine insulin increases plasma membrane K(ATP) channel via PI3K-VAMP2 pathway in MIN6 cells by Xu, Shanhua, Kim, Ji-Hee, Hwang, Kyu-Hee, Das, Ranjan, Quan, Xianglan, Nguyen, Tuyet Thi, Kim, Soo-Jin, Cha, Seung-Kuy, Park, Kyu-Sang

“…Regulation of ATP-sensitive inwardly rectifying potassium (KATP) channel plays a critical role in metabolism-secretion coupling of pancreatic β-cells. Released…”
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