Search Results - "Quan, Songhua"

Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter by Zhu, Yueming, Zou, Xianghui, Dean, Angela E., Brien, Joseph O’, Gao, Yucheng, Tran, Elizabeth L., Park, Seong-Hoon, Liu, Guoxiang, Kieffer, Matthew B., Jiang, Haiyan, Stauffer, Melissa E., Hart, Robert, Quan, Songhua, Satchell, Karla J. F., Horikoshi, Nobuo, Bonini, Marcelo, Gius, David

“…Manganese superoxide dismutase (MnSOD) functions as a tumor suppressor; however, once tumorigenesis occurs, clinical data suggest MnSOD levels correlate with…”
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Mechanism-centric regulatory network identifies NME2 and MYC programs as markers of Enzalutamide resistance in CRPC by Panja, Sukanya, Truica, Mihai Ioan, Yu, Christina Y., Saggurthi, Vamshi, Craige, Michael W., Whitehead, Katie, Tuiche, Mayra V., Al-Saadi, Aymen, Vyas, Riddhi, Ganesan, Shridar, Gohel, Suril, Coffman, Frederick, Parrott, James S., Quan, Songhua, Jha, Shantenu, Kim, Isaac, Schaeffer, Edward, Kothari, Vishal, Abdulkadir, Sarki A., Mitrofanova, Antonina

“…Heterogeneous response to Enzalutamide, a second-generation androgen receptor signaling inhibitor, is a central problem in castration-resistant prostate cancer…”
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Loss of Sirt2 increases and prolongs a caerulein-induced pancreatitis permissive phenotype and induces spontaneous oncogenic Kras mutations in mice by Quan, Songhua, Principe, Daniel R., Dean, Angela E., Park, Seong-Hoon, Grippo, Paul J., Gius, David, Horikoshi, Nobuo

“…Mice lacking Sirt2 spontaneously develop tumors in multiple organs, as well as when expressed in combination with oncogenic Kras G12D , leading to pancreatic…”
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CD1dhiCD5+ B Cells Expanded by GM-CSF In Vivo Suppress Experimental Autoimmune Myasthenia Gravis by Sheng, Jian Rong, Quan, Songhua, Soliven, Betty

“…Abstract IL-10–competent subset within CD1dhiCD5+ B cells, also known as B10 cells, has been shown to regulate autoimmune diseases. Whether B10 cells can…”
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Epigenetic contribution to cancer by Quan, Songhua, Huang, Hao

“…Epigenetics has transformed our understanding of cancer by revealing how changes in gene activity, which do not alter the DNA itself, can initiate and progress…”
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CD1d(hi)CD5+ B cells expanded by GM-CSF in vivo suppress experimental autoimmune myasthenia gravis by Sheng, Jian Rong, Quan, Songhua, Soliven, Betty

“…IL-10-competent subset within CD1d(hi)CD5(+) B cells, also known as B10 cells, has been shown to regulate autoimmune diseases. Whether B10 cells can prevent or…”
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Effect of madecassic acid on retinal oxidative stress, inflammation and Growth Factors in streptozotocin-induced diabetic rats by Wang, Xuelin, Guo, Li, Zhang, Wei, Song, Yuan, Almoallim, Hesham S., Aljawdah, Hossam M., Quan, Songhua

“…Diabetic retinopathy (DR) is the leading cause of blindness and visual loss in people with diabetes. It has been suggested that the progression of DR is…”
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Complex dietary polysaccharide modulates gut immune function and microbiota, and promotes protection from autoimmune diabetes by Gudi, Radhika, Perez, Nicolas, Johnson, Benjamin M., Sofi, M. Hanief, Brown, Robert, Quan, Songhua, Karumuthil‐Melethil, Subha, Vasu, Chenthamarakshan

“…Summary The dietary supplement and prebiotic values of β‐glucan‐rich products have been widely recognized and dietary approaches for modulating autoimmunity…”
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IL-10 derived from CD1dhiCD5+ B cells regulates experimental autoimmune myasthenia gravis by Sheng, Jian Rong, Quan, Songhua, Soliven, Betty

“…IL-10-competent subset within CD1dhiCD5+ B cells, also known as B10 cells, has been shown to regulate autoimmune diseases. In our previous study, adoptive…”
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Asparagine Dependency is a Targetable Metabolic Vulnerability in TP53-Altered Castration-Resistant Prostate Cancer by Yoo, Young A, Quan, Songhua, Yang, William, Guo, Qianyu, Rodríguez, Yara, Chalmers, Zachary R, Dufficy, Mary F, Lackie, Barbara, Sagar, Vinay, Unno, Kenji, Truica, Mihai I, Chandel, Navdeep S, Abdulkadir, Sarki A

“…The TP53 tumor suppressor is frequently altered in lethal, castration-resistant prostate cancer (CRPC). However, to date there are no effective treatments that…”
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GM-CSF-expanded CD1dhiCD5+ B cells suppress experimental autoimmune myasthenia gravis (THER3P.886) by Sheng, Jian Rong, Quan, Songhua, Soliven, Betty

“…Abstract IL-10-competent subset within CD1dhiCD5+ B cells, also known as B10 cells, has been shown to regulate autoimmune diseases. Whether B10 cells can…”
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IL-10 derived from CD1dhi CD5+ B cells regulates experimental autoimmune myasthenia gravis by Sheng, Jian Rong, Quan, Songhua, Soliven, Betty

“…Abstract IL-10-competent subset within CD1dhi CD5+ B cells, also known as B10 cells, has been shown to regulate autoimmune diseases. In our previous study,…”
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Insights into the mechanism of oligodendrocyte protection and remyelination enhancement by the integrated stress response by Chen, Yanan, Quan, Songhua, Patil, Vaibhav, Kunjamma, Rejani B., Tokars, Haley M., Leisten, Eric D., Joy, Godwin, Wills, Samantha, Chan, Jonah R., Wong, Yvette C., Popko, Brian

“…central nervous system (CNS) inflammation triggers activation of the integrated stress response (ISR). We previously reported that prolonging the ISR protects…”
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MnSOD Lysine 68 acetylation leads to cisplatin and doxorubicin resistance due to aberrant mitochondrial metabolism by Gao, Yucheng, Zhu, Yueming, Tran, Elizabeth L, Tokars, Valerie, Dean, Angela E, Quan, Songhua, Gius, David

“…Manganese superoxide dismutase (MnSOD) acetylation (Ac) has been shown to be a key post-translational modification important in the regulation of…”
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Impaired dendritic cell function in a spontaneous autoimmune polyneuropathy by Quan, Songhua, Kim, Hye-Jung, Dukala, Danuta, Sheng, Jian Rong, Soliven, Betty

“…Spontaneous autoimmune polyneuropathy (SAP) in B7-2 knockout NOD mice mimics the progressive form of chronic inflammatory demyelinating polyradiculoneuropathy,…”
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Temperature Characteristics Improvement of Power Battery Module for Electric Vehicles by Jian Wang, Zhengbin Wu, Xianquan Deng, Songhua Quan, Xiaoping Yang

“…Power battery module under high-rate discharge conditions produces thermal aggregation phenomena. Generated heat during charging and discharging that…”
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Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered metabolism, cell senescence, and nonalcoholic fatty liver disease by Xu, Guogang, Quan, Songhua, Schell, Joseph, Gao, Yucheng, Varmazyad, Mahboubeh, Sreenivas, Prethish, Cruz, Diego, Jiang, Haiyan, Pan, Meixia, Han, Xianlin, Palavicini, Juan Pablo, Zhao, Peng, Sun, Xiaoli, Marchant, Erik D, Rasmussen, Blake B, Li, Guannan, Katsumura, Sakie, Morita, Masahiro, Munkácsy, Erin, Horikoshi, Nobuo, Chocron, E Sandra, Gius, David

“…Acetyl-CoA synthetase short-chain family member 1 (ACSS1) uses acetate to generate mitochondrial acetyl-CoA and is regulated by deacetylation by sirtuin 3. We…”
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