Search Results - "Quaife, M. M."

The Translational Landscape of the Human Heart by van Heesch, Sebastiaan, Witte, Franziska, Schneider-Lunitz, Valentin, Schulz, Jana F., Adami, Eleonora, Faber, Allison B., Kirchner, Marieluise, Maatz, Henrike, Blachut, Susanne, Sandmann, Clara-Louisa, Kanda, Masatoshi, Worth, Catherine L., Schafer, Sebastian, Calviello, Lorenzo, Merriott, Rhys, Patone, Giannino, Hummel, Oliver, Wyler, Emanuel, Obermayer, Benedikt, Mücke, Michael B., Lindberg, Eric L., Trnka, Franziska, Memczak, Sebastian, Schilling, Marcel, Felkin, Leanne E., Barton, Paul J.R., Quaife, Nicholas M., Vanezis, Konstantinos, Diecke, Sebastian, Mukai, Masaya, Mah, Nancy, Oh, Su-Jun, Kurtz, Andreas, Schramm, Christoph, Schwinge, Dorothee, Sebode, Marcial, Harakalova, Magdalena, Asselbergs, Folkert W., Vink, Aryan, de Weger, Roel A., Viswanathan, Sivakumar, Widjaja, Anissa A., Gärtner-Rommel, Anna, Milting, Hendrik, dos Remedios, Cris, Knosalla, Christoph, Mertins, Philipp, Landthaler, Markus, Vingron, Martin, Linke, Wolfgang A., Seidman, Jonathan G., Seidman, Christine E., Rajewsky, Nikolaus, Ohler, Uwe, Cook, Stuart A., Hubner, Norbert

“…Gene expression in human tissue has primarily been studied on the transcriptional level, largely neglecting translational regulation. Here, we analyze the…”
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Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins by Chothani, Sonia, Schäfer, Sebastian, Adami, Eleonora, Viswanathan, Sivakumar, Widjaja, Anissa A, Langley, Sarah R, Tan, Jessie, Wang, Mao, Quaife, Nicholas M, Jian Pua, Chee, D’Agostino, Giuseppe, Guna Shekeran, Shamini, George, Benjamin L, Lim, Stella, Yiqun Cao, Elaine, van Heesch, Sebastiaan, Witte, Franziska, Felkin, Leanne E, Christodoulou, Eleni G, Dong, Jinrui, Blachut, Susanne, Patone, Giannino, Barton, Paul J.R, Hubner, Norbert, Cook, Stuart A, Rackham, Owen J.L

“…BACKGROUND:Fibrosis is a common pathology in many cardiac disorders and is driven by the activation of resident fibroblasts. The global posttranscriptional…”
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Food choice responses to changes in the price of a staple crop: a discrete choice experiment of maize in rural Malawi by Matita, M., Mazalale, J., Quaife, M., Johnston, D., Cornelsen, L., Kamwanja, T., Smith, R., Walls, H.

“…Price and affordability are important drivers of food choice, particularly for rural smallholder farming households in Malawi, experiencing extreme poverty,…”
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The household economic burden of drug-susceptible TB diagnosis and treatment in The Gambia by Devoid, I., Sillah, A. K., Sutherland, J., Owolabi, O., Ivanova, O., Govathson, C., Hirasen, K., Davies, M., Lönnroth, K., Loum, I., Touray, A., Charlambous, S., Evans, D., Quaife, M.

“…OBJECTIVE: To determine the costs and catastrophic costs incurred by drug-susceptible (DS) pulmonary TB patients in The Gambia.METHODS: This observational…”
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Patient preferences for key drivers and facilitators of adoption of mHealth technology to manage depression: A discrete choice experiment by Simblett, S.K., Pennington, M., Quaife, M., Siddi, S., Lombardini, F., Haro, J.M., Peñarrubia-Maria, M.T., Bruce, S., Nica, R., Zorbas, S., Polhemus, A., Novak, J., Dawe-Lane, E., Morris, D., Mutepua, M., Odoi, C., Wilson, E., Matcham, F., White, K.M., Hotopf, M., Wykes, T.

“…In time, we may be able to detect the early onset of symptoms of depression and even predict relapse using behavioural data gathered through mobile…”
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Correction to: Food choice responses to changes in the price of a staple crop: a discrete choice experiment of maize in rural Malawi by Matita, M., Mazalale, J., Quaife, M., Johnston, D., Cornelsen, L., Kamwanja, T., Smith, R., Walls, H.

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Digital adherence technology for TB: focus on livelihoods as well as lives by McQuaid, C. F., Foster, N., Quaife, M., Levy, J., Tadesse, A. W., Charalambous, S., Alacapa, J. V., Deyanova, N., Mganga, A., Houben, R. M. G. J., Fielding, K. L.

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Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals by Whiffin, Nicola, Karczewski, Konrad J., Zhang, Xiaolei, Chothani, Sonia, Smith, Miriam J., Evans, D. Gareth, Roberts, Angharad M., Quaife, Nicholas M., Schafer, Sebastian, Rackham, Owen, Alföldi, Jessica, O’Donnell-Luria, Anne H., Francioli, Laurent C., Cook, Stuart A., Barton, Paul J. R., MacArthur, Daniel G., Ware, James S.

“…Upstream open reading frames (uORFs) are tissue-specific cis -regulators of protein translation. Isolated reports have shown that variants that create or…”
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Considering equity in priority setting using transmission models: Recommendations and data needs by Quaife, M., Medley, GF, Jit, M., Drake, T., Asaria, M., van Baal, P., Baltussen, R., Bollinger, L., Bozzani, F., Brady, O., Broekhuizen, H., Chalkidou, K., Chi, Y.-L., Dowdy, DW, Griffin, S., Haghparast-Bidgoli, H., Hallett, T., Hauck, K., Hollingsworth, TD, McQuaid, CF, Menzies, NA, Merritt, MW, Mirelman, A., Morton, A., Ruiz, FJ, Siapka, M., Skordis, J., Tediosi, F., Walker, P., White, RG, Winskill, P., Vassall, A., Gomez, GB

“…Disease transmission models are used in impact assessment and economic evaluations of infectious disease prevention and treatment strategies, prominently so in…”
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Smartphone-Based Remote Monitoring for Chronic Heart Failure: Mixed Methods Analysis of User Experience From Patient and Nurse Perspectives by Auton, Alice, Zaman, Sameer, Padayachee, Yorissa, Samways, Jack W, Quaife, Nicholas M, Sweeney, Mark, Tenorio, Indira, Linton, Nick W F, Cole, Graham D, Peters, Nicholas S, Mayet, Jamil, Barton, Carys, Plymen, Carla

“…Community-based management by heart failure specialist nurses (HFSNs) is key to improving self-care in heart failure with reduced ejection fraction. Remote…”
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Smartphone-Based Remote Monitoring in Heart Failure With Reduced Ejection Fraction: Retrospective Cohort Study of Secondary Care Use and Costs by Zaman, Sameer, Padayachee, Yorissa, Shah, Moulesh, Samways, Jack, Auton, Alice, Quaife, Nicholas M, Sweeney, Mark, Howard, James P, Tenorio, Indira, Bachtiger, Patrik, Kamalati, Tahereh, Pabari, Punam A, Linton, Nick W F, Mayet, Jamil, Peters, Nicholas S, Barton, Carys, Cole, Graham D, Plymen, Carla M

“…Despite effective therapies, the economic burden of heart failure with reduced ejection fraction (HFrEF) is driven by frequent hospitalizations. Treatment…”
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Author Correction: Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals by Whiffin, Nicola, Karczewski, Konrad J., Zhang, Xiaolei, Chothani, Sonia, Smith, Miriam J., Evans, D. Gareth, Roberts, Angharad M., Quaife, Nicholas M., Schafer, Sebastian, Rackham, Owen, Alföldi, Jessica, O’Donnell-Luria, Anne H., Francioli, Laurent C., Cook, Stuart A., Barton, Paul J. R., MacArthur, Daniel G., Ware, James S.

“…A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21052-3…”
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Non-coding region variants upstream of MEF2C cause severe developmental disorder through three distinct loss-of-function mechanisms by Wright, Caroline F., Quaife, Nicholas M., Ramos-Hernández, Laura, Danecek, Petr, Ferla, Matteo P., Samocha, Kaitlin E., Kaplanis, Joanna, Gardner, Eugene J., Eberhardt, Ruth Y., Chao, Katherine R., Karczewski, Konrad J., Morales, Joannella, Gallone, Giuseppe, Balasubramanian, Meena, Banka, Siddharth, Gompertz, Lianne, Kerr, Bronwyn, Kirby, Amelia, Lynch, Sally A., Morton, Jenny E.V., Pinz, Hailey, Sansbury, Francis H., Stewart, Helen, Zuccarelli, Britton D., Cook, Stuart A., Taylor, Jenny C., Juusola, Jane, Retterer, Kyle, Firth, Helen V., Hurles, Matthew E., Lara-Pezzi, Enrique, Barton, Paul J.R., Whiffin, Nicola

“…Clinical genetic testing of protein-coding regions identifies a likely causative variant in only around half of developmental disorder (DD) cases. The…”
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LINC01013 Is a Determinant of Fibroblast Activation and Encodes a Novel Fibroblast-Activating Micropeptide by Quaife, N. M., Chothani, S., Schulz, J. F., Lindberg, E. L., Vanezis, K., Adami, E., O’Fee, K., Greiner, J., Litviňuková, M., van Heesch, S., Whiffin, N., Hubner, N., Schafer, S., Rackham, O., Cook, S. A., Barton, P. J. R.

“…Myocardial fibrosis confers an almost threefold mortality risk in heart disease. There are no prognostic therapies and novel therapeutic targets are needed…”
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Correction to: LINC01013 Is a Determinant of Fibroblast Activation and Encodes a Novel Fibroblast-Activating Micropeptide by Quaife, N. M., Chothani, S., Schulz, J. F., Lindberg, E. L., Vanezis, K., Adami, E., O’Fee, K., Greiner, J., Litviňuková, M., van Heesch, S., Whiffin, N., Hubner, N., Schafer, S., Rackham, O., Cook, S. A., Barton, P. J. R.

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PCR96 Exploring Patient Preferences through Cross-Sectional Discrete Choice Experiment: An Insight into Once-Daily Stroke Prevention Treatments in Atrial Fibrillation in Asia by Wang, R, Lu, H, Fernandez, G, Higashiyama, H, Du, J, Ye, X, Quaife, M

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Zebrafish: an emerging model of vascular development and remodelling by Quaife, Nicholas M, Watson, Oliver, Chico, Timothy JA

“…Highlights ► Zebrafish are small, cheap, and easy to maintain. ► Zebrafish embryos develop independently, are transparent and extremely genetically tractable…”
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PCR234 Patient and Oncologist Preferences for Anaplastic Lymphoma Kinase Positive Advanced Non-Small Cell Lung Cancer (ALK+ aNSCLC) Tyrosine Kinase Inhibitors (TKIs) Treatments in the First Line (1L) Setting by Le, H, Coulter, J, Cappelleri, J, Lu, H, Quaife, M, Meginnis, K, Fernandez, G, Culver, KW, Vaghela, S, Thomaidou, D, Stinchcombe, T

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PCR141 Smoldering Multiple Myeloma: A Multi-Country Mixed-Methods Study on Disease Perceptions and Patient Treatment Preferences by Quaife, M, Jimenez-Moreno, C, Otero B, Gros, Asra, A, Gupta-Werner, N, Gries, KS, Leisten, MK, Matt, K, Carson, R, Dennis, R, He, J, Levitan, B, Bathija, S

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PRM97 - Accounting for the Imperfect External Validity of Discrete Choice Experiments When Predicting Demand by Quaife, M, Terris-Prestholt, F, Di Tanna, GL, Vickerman, P

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