Search Results - "Quach, Tam"

Human B-1 cells take the stage by Rothstein, Thomas L., Griffin, Daniel O., Holodick, Nichol E., Quach, Tam D., Kaku, Hiroaki

“…B‐1 cells play critical roles in defending against microbial invasion and in housekeeping removal of cellular debris. B‐1 cells secrete natural antibody and…”
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Human B-1 Cells and B-1 Cell Antibodies Change With Advancing Age by Rodriguez-Zhurbenko, Nely, Quach, Tam D, Hopkins, Thomas J, Rothstein, Thomas L, Hernandez, Ana M

“…Age-related deficits in the immune system have been associated with an increased incidence of infections, autoimmune diseases, and cancer. Human B cell…”
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The extracellular matrix protects Pseudomonas aeruginosa biofilms by limiting the penetration of tobramycin by Tseng, Boo Shan, Zhang, Wei, Harrison, Joe J., Quach, Tam P., Song, Jisun Lee, Penterman, Jon, Singh, Pradeep K., Chopp, David L., Packman, Aaron I., Parsek, Matthew R.

“…Summary Biofilm cells are less susceptible to antimicrobials than their planktonic counterparts. While this phenomenon is multifactorial, the ability of the…”
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Combination CTLA4Ig and Anti-CD40 Ligand Treatment Modifies T and B Cell Metabolic Profiles and Promotes B Cell Receptor Remodeling in a Mouse Model of Systemic Lupus Erythematosus by Raparia, Chirag, Quach, Tam D, Zeumer-Spataro, Leilani, Choi, Seung-Chul, Yi, Zhengzi, Zhang, Weijia, Morel, Laurence, Davidson, Anne

“…Systemic lupus erythematosus is a complex autoimmune disease with significant morbidity that demands further examination of tolerance-inducing treatments…”
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Human B-1 cells are important contributors to the naturally-occurring IgM pool against the tumor-associated ganglioside Neu5GcGM3 by Rodriguez-Zhurbenko, Nely, Quach, Tam D, Rothstein, Thomas L, Hernandez, Ana M

“…Only few studies have described the anti-tumor properties of natural antibodies (NAbs). In particular, natural IgM have been linked to cancer…”
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Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis by Weber, Georg F, Chousterman, Benjamin G, Hilgendorf, Ingo, Robbins, Clinton S, Theurl, Igor, Gerhardt, Louisa M S, Iwamoto, Yoshiko, Quach, Tam D, Ali, Muhammad, Chen, John W, Rothstein, Thomas L, Nahrendorf, Matthias, Weissleder, Ralph, Swirski, Filip K

“…Pneumonia is a major cause of mortality worldwide and a serious problem in critical care medicine, but the immunophysiological processes that confer either…”
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The human counterpart of mouse B-1 cells by Rothstein, Thomas L., Quach, Tam D.

“…B‐1 cells represent a subpopulation of B cells that has been extensively studied in mice and shown to spontaneously generate natural antibody that provides…”
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Intellectual disability: dendritic anomalies and emerging genetic perspectives by Quach, Tam T., Stratton, Harrison J., Khanna, Rajesh, Kolattukudy, Pappachan E., Honnorat, Jérome, Meyer, Kathrin, Duchemin, Anne-Marie

“…Intellectual disability (ID) corresponds to several neurodevelopmental disorders of heterogeneous origin in which cognitive deficits are commonly associated…”
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Low Levels of IgM Antibodies against an Advanced Glycation Endproduct-Modified Apolipoprotein B100 Peptide Predict Cardiovascular Events in Nondiabetic Subjects by Engelbertsen, Daniel, Vallejo, Jenifer, Quách, Tâm Dan, Fredrikson, Gunilla Nordin, Alm, Ragnar, Hedblad, Bo, Björkbacka, Harry, Rothstein, Thomas L, Nilsson, Jan, Bengtsson, Eva

“…Increased glucose levels are associated with the generation of advanced glycation endproduct (AGE) modifications. Interaction between AGE-modified plaque…”
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Neurodegenerative Diseases: From Dysproteostasis, Altered Calcium Signalosome to Selective Neuronal Vulnerability to AAV-Mediated Gene Therapy by Quach, Tam T, Stratton, Harrison J, Khanna, Rajesh, Mackey-Alfonso, Sabrina, Deems, Nicolas, Honnorat, Jérome, Meyer, Kathrin, Duchemin, Anne-Marie

“…Despite intense research into the multifaceted etiology of neurodegenerative diseases (ND), they remain incurable. Here we provide a brief overview of several…”
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Novel Human Transitional B Cell Populations Revealed by B Cell Depletion Therapy by Palanichamy, Arumugam, Barnard, Jennifer, Zheng, Bo, Owen, Teresa, Quach, Tam, Wei, Chungwen, Looney, R. John, Sanz, Inaki, Anolik, Jennifer H

“…Transitional cells represent a crucial step in the differentiation and selection of the mature B cell compartment. Human transitional B cells have previously…”
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Collapsin Response Mediator Proteins: Novel Targets for Alzheimer's Disease by Quach, Tam T, Moutal, Aubin, Khanna, Rajesh, Deems, Nicholas P, Duchemin, Anne-Marie, Barrientos, Ruth M

“…Numerous experimental and postmortem studies have increasingly reported dystrophic axons and dendrites, and alterations of dendritic spine morphology and…”
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Belimumab promotes negative selection of activated autoreactive B cells in systemic lupus erythematosus patients by Huang, Weiqing, Quach, Tam D, Dascalu, Cosmin, Liu, Zheng, Leung, Tungming, Byrne-Steele, Miranda, Pan, Wenjing, Yang, Qunying, Han, Jian, Lesser, Martin, Rothstein, Thomas L, Furie, Richard, Mackay, Meggan, Aranow, Cynthia, Davidson, Anne

“…Belimumab has therapeutic benefit in active systemic lupus erythematosus (SLE), especially in patients with high-titer anti-dsDNA antibodies. We asked whether…”
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Genetic landscape of recessive diseases in the Vietnamese population from large‐scale clinical exome sequencing by Tran, Ngoc Hieu, Nguyen Thi, Thanh‐Huong, Tang, Hung‐Sang, Hoang, Le‐Phuc, Nguyen, Trung‐Hieu Le, Tran, Nhat‐Thang, Trinh, Thu‐Huong Nhat, Nguyen, Van Thong, Nguyen, Bao‐Han Huu, Nguyen, Hieu Trong, Doan, Loc Phuoc, Phan, Ngoc‐Minh, Nguyen, Kim‐Huong Thi, Nguyen, Hong‐Dang Luu, Quach, Minh‐Tam Thi, Nguyen, Thanh‐Phuong Thi, Tran, Vu Uyen, Tran, Dinh‐Vinh, Nguyen, Quynh‐Tho Thi, Do, Thanh‐Thuy Thi, Lam, Nien Vinh, Cao Thi Ngoc, Phuong, Truong, Dinh Kiet, Nguyen, Hoai‐Nghia, Phan, Minh‐Duy, Giang, Hoa

“…Accurate profiling of population‐specific recessive diseases is essential for the design of cost‐effective carrier screening programs. However, minority…”
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Opposing Morphogenetic Defects on Dendrites and Mossy Fibers of Dentate Granular Neurons in CRMP3-Deficient Mice by Quach, Tam T, Auvergnon, Nathalie, Khanna, Rajesh, Belin, Marie-Françoise, Kolattukudy, Papachan E, Honnorat, Jérome, Duchemin, Anne-Marie

“…Collapsin response mediator proteins (CRMPs) are highly expressed in the brain during early postnatal development and continue to be present in specific…”
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Context-dependent induction of autoimmunity by TNF signaling deficiency by Quach, Tam D, Huang, Weiqing, Sahu, Ranjit, Diadhiou, Catherine Mm, Raparia, Chirag, Johnson, Roshawn, Leung, Tung Ming, Malkiel, Susan, Ricketts, Peta Gay, Gallucci, Stefania, Tükel, Çagla, Jacob, Chaim O, Lesser, Martin L, Zou, Yong-Rui, Davidson, Anne

“…TNF inhibitors are widely used to treat inflammatory diseases; however, 30%-50% of treated patients develop new autoantibodies, and 0.5%-1% develop secondary…”
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Mapping CRMP3 domains involved in dendrite morphogenesis and voltage-gated calcium channel regulation by Quach, Tam T, Wilson, Sarah M, Rogemond, Veronique, Chounlamountri, Naura, Kolattukudy, Pappachan E, Martinez, Stephanie, Khanna, May, Belin, Marie-Francoise, Khanna, Rajesh, Honnorat, Jerome, Duchemin, Anne-Marie

“…Although hippocampal neurons are well-distinguished by the morphological characteristics of their dendrites and their structural plasticity, the mechanisms…”
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Stress Increases Peripheral Axon Growth and Regeneration through Glucocorticoid Receptor-Dependent Transcriptional Programs by Lerch, Jessica K, Alexander, Jessica K, Madalena, Kathryn M, Motti, Dario, Quach, Tam, Dhamija, Akhil, Zha, Alicia, Gensel, John C, Webster Marketon, Jeanette, Lemmon, Vance P, Bixby, John L, Popovich, Phillip G

“…Stress and glucocorticoid (GC) release are common behavioral and hormonal responses to injury or disease. In the brain, stress/GCs can alter neuron structure…”
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CRMP3 is required for hippocampal CA1 dendritic organization and plasticity by Quach, Tam T, Massicotte, Guy, Belin, Marie-Françoise, Honnorat, Jérome, Glasper, Erica R, Devries, Anne C, Jakeman, Lyn B, Baudry, Michel, Duchemin, Anne-Marie, Kolattukudy, Pappachan E

“…In vitro studies have pointed to the collapsin response mediator proteins (CRMPs) as key regulators of neurite outgrowth and axonal differentiation. CRMP3 is…”
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Neuronal networks in mental diseases and neuropathic pain: Beyond brain derived neurotrophic factor and collapsin response mediator proteins by Quach, Tam T, Lerch, Jessica K, Honnorat, Jerome, Khanna, Rajesh, Duchemin, Anne-Marie

“…The brain is a complex network system that has the capacity to support emotion, thought, action, learning and memory, and is characterized by constant…”
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