Search Results - "Quach, Alex"
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The Application of Dextran Sedimentation as an Initial Step in Neutrophil Purification Promotes Their Stimulation, due to the Presence of Monocytes
Published in Journal of immunology research (01-01-2017)“…The purification of human neutrophils for in vitro studies is challenging as they are easily activated through ex vivo manipulations. The technique of…”
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Small tumor necrosis factor receptor biologics inhibit the tumor necrosis factor-p38 signalling axis and inflammation
Published in Nature communications (10-04-2018)“…Despite anti-TNF therapy advancements for inflammatory diseases such as rheumatoid arthritis, the burden of diseases remains high. An 11-mer TNF peptide, TNF…”
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Characterization of the Transient Deficiency of PKC Isozyme Levels in Immature Cord Blood T Cells and Its Connection to Anti-Allergic Cytokine Profiles of the Matured Cells
Published in International journal of molecular sciences (23-11-2021)“…Cord blood T cells (CBTC) from a proportion of newborns express low/deficient levels of some protein kinase C (PKC) isozymes, with low levels of PKCζ…”
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Cord Blood T Cells Expressing High and Low PKCζ Levels Develop into Cells with a Propensity to Display Th1 and Th9 Cytokine Profiles, Respectively
Published in International journal of molecular sciences (01-05-2021)“…Low Protein Kinase C zeta (PKCζ) levels in cord blood T cells (CBTC) have been shown to correlate with the development of allergic sensitization in childhood…”
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Cytokines regulate complement receptor immunoglobulin expression and phagocytosis of Candida albicans in human macrophages: A control point in anti-microbial immunity
Published in Scientific reports (22-06-2017)“…Complement Receptor Immunoglobulin (CRIg), selectively expressed by macrophages, plays an important role in innate immunity by promoting phagocytosis of…”
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Neutrophils Require Activation to Express Functional Cell-Surface Complement Receptor Immunoglobulin
Published in Frontiers in immunology (04-03-2022)“…The phagocytosis-promoting complement receptor, Complement Receptor Immunoglobulin (CRIg), is exclusively expressed on macrophages. It has been demonstrated…”
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Human Dendritic Cells Express the Complement Receptor Immunoglobulin Which Regulates T Cell Responses
Published in Frontiers in immunology (10-12-2019)“…The B7 family-related protein V-set and Ig containing 4 (VSIG4), also known as Z39Ig and Complement Immunoglobulin Receptor (CRIg), is the most recent of the…”
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Vitamin D upregulates the macrophage complement receptor immunoglobulin in innate immunity to microbial pathogens
Published in Communications biology (25-03-2021)“…Vitamin D deficiency remains a global concern. This ‘sunshine’ vitamin is converted through a multistep process to active 1,25-dihydroxyvitamin D 3 (1,25D),…”
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Investigations on the mechanism of NLRP3 inflammasome gain-of-function through molecular dynamics simulation
Published in Pathology (01-02-2024)Get full text
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Complement receptor immunoglobulin: a control point in infection and immunity, inflammation and cancer
Published in Swiss medical weekly (05-04-2016)Get full text
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Effects of blood sample storage time, temperature, anti-coagulants and blood stabiliser on lymphocyte phenotyping
Published in Pathology (01-06-2024)“…Medical diagnostic laboratories have come under further scrutiny to ensure quality standards of their service and external quality assurance (EQA) programs…”
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Effects of blood sample storage time, temperature, anti-coagulants and blood stabiliser on lymphocyte phenotyping
Published in Pathology (01-02-2024)Get full text
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Rapid functional assessment of a suspected pathogenic NLRP3 gene variant in a family with a CAPS phenotype
Published in Pathology (01-03-2022)Get full text
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Current perspectives on serum cytokine testing in immunopathology
Published in Pathology (01-02-2024)Get full text
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An immunodeficiency tale: same mutation, different phenotype
Published in Pathology (01-02-2023)Get full text
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PKCζ activation promotes maturation of cord blood T cells towards a Th1 IFN-γ propensity
Published in Immunology (01-11-2023)“…A significant number of babies present transiently with low protein kinase C zeta (PKCζ) levels in cord blood T cells (CBTC), associated with reduced ability…”
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Delayed Blood Processing Leads to Rapid Deterioration in the Measurement of the Neutrophil Respiratory Burst by the Dihydrorhodamine‐123 Reduction Assay
Published in Cytometry. Part B, Clinical cytometry (01-09-2019)“…Background Neutrophils ex vivo in whole blood specimens are widely understood to decay rapidly when compared to other leukocytes, requiring assessment of…”
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Vitamin D promotes anti-microbial activity of macrophages via Complement Receptor Immunoglobulin
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract Vitamin D deficiency remains of major global concern, affecting up to half of the population at some stage of life. Although the use of vitamin D to…”
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Facilitating THP-1 macrophage studies by differentiating and investigating cell functions in polystyrene test tubes
Published in Journal of immunological methods (01-10-2018)“…Macrophage cell lines are a useful model to explore the properties of primary macrophages. However, a major limitation in the use of these cells is that when…”
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Socioeconomic Status, Ethnicity, Culture, and Immigration: Examining the Potential Mechanisms Underlying Mexican-Origin Adolescents' Organized Activity Participation
Published in Developmental psychology (01-04-2013)“…The integrative model for child development and ecodevelopmental theory suggest that macro factors, such as socioeconomic status, ethnicity, culture, and…”
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