Search Results - "Qu, Yuan‐Yuan"

LncRNA H19 promotes triple-negative breast cancer cells invasion and metastasis through the p53/TNFAIP8 pathway by Li, Yang, Ma, Hong-Yu, Hu, Xiao-Wei, Qu, Yuan-Yuan, Wen, Xin, Zhang, Yu, Xu, Qing-Yong

“…Long non-coding RNA H19 (lncRNA H19) has been implicated in tumorigenesis and metastasis of breast cancer through regulating epithelial to mesenchymal…”
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Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation by Zhang, Xuan, Qu, Yuan-Yuan, Liu, Lian, Qiao, Ya-Nan, Geng, Hao-Ran, Lin, Yan, Xu, Wei, Cao, Jing, Zhao, Jian-Yuan

“…Elevation in homocysteine (Hcy) level is associated with insulin resistance; however, the causality between them and the underlying mechanism remain elusive…”
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Large‐scale transcriptome profiles reveal robust 20‐signatures metabolic prediction models and novel role of G6PC in clear cell renal cell carcinoma by Xu, Wen‐Hao, Xu, Yue, Tian, Xi, Anwaier, Aihetaimujiang, Liu, Wang‐Rui, Wang, Jun, Zhu, Wen‐Kai, Cao, Da‐Long, Wang, Hong‐Kai, Shi, Guo‐Hai, Qu, Yuan‐Yuan, Zhang, Hai‐Liang, Ye, Ding‐Wei

“…Clear cell renal cell carcinoma (ccRCC) is the most common and highly malignant pathological type of kidney cancer. We sought to establish a metabolic…”
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Research on Large-Scale Bi-Level Particle Swarm Optimization Algorithm by Jiang, Jia-Jia, Wei, Wen-Xue, Shao, Wan-Lu, Liang, Yu-Feng, Qu, Yuan-Yuan

“…Targeting at the slow convergence and the local optimum problems of particle swarm optimization (PSO), a large-scale bi-level particle swarm optimization…”
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Construction of a robust prognostic model for adult adrenocortical carcinoma: Results from bioinformatics and real‐world data by Tian, Xi, Xu, Wen‐Hao, Anwaier, Aihetaimujiang, Wang, Hong‐Kai, Wan, Fang‐Ning, Cao, Da‐Long, Luo, Wen‐Jie, Shi, Guo‐Hai, Qu, Yuan‐Yuan, Zhang, Hai‐Liang, Ye, Ding‐Wei

“…This study aims to construct a robust prognostic model for adult adrenocortical carcinoma (ACC) by large‐scale multiomics analysis and real‐world data. The…”
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Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients by Zhang, Ya-Kun, Qu, Yuan-Yuan, Lin, Yan, Wu, Xiao-Hui, Chen, Hou-Zao, Wang, Xu, Zhou, Kai-Qiang, Wei, Yun, Guo, Fushen, Yao, Cui-Fang, He, Xia-Di, Liu, Li-Xia, Yang, Chen, Guan, Zong-Yuan, Wang, Shi-Dong, Zhao, Jianyuan, Liu, De-Pei, Zhao, Shi-Min, Xu, Wei

“…The oncogenic mechanisms of overnutrition, a confirmed independent cancer risk factor, remain poorly understood. Herein, we report that enoyl-CoA hydratase-1…”
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Heterogeneity in tertiary lymphoid structures predicts distinct prognosis and immune microenvironment characterizations of clear cell renal cell carcinoma by Xu, Wenhao, Lu, Jiahe, Liu, Wang-Rui, Anwaier, Aihetaimujiang, Wu, Yuhao, Tian, Xi, Su, Jia-Qi, Qu, Yuan-Yuan, Yang, Jianfeng, Zhang, Hailiang, Ye, Dingwei

“…BackgroundTertiary lymphoid structures (TLS) are organized aggregates of immune cells that develop postnatally in non-lymphoid tissues and are associated with…”
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Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer by Wang, Shuo, Qu, Yuan, Xia, Pengyan, Chen, Yi, Zhu, Xiaoxiao, Zhang, Jing, Wang, Guan, Tian, Yong, Ying, Jianming, Fan, Zusen

“…Innate lymphoid cells (ILCs) reside in mucosal surfaces to potentiate immune responses, sustain mucosal integrity and maintain tissue homeostasis. However, how…”
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Camrelizumab plus famitinib for advanced or metastatic urothelial carcinoma after platinum-based therapy: data from a multicohort phase 2 study by Qu, Yuan-Yuan, Sun, Zhongquan, Han, Weiqing, Zou, Qing, Xing, Nianzeng, Luo, Hong, Zhang, Xuepei, He, Chaohong, Bian, Xiao-Jie, Cai, Jinling, Chen, Chunxia, Wang, Quanren, Ye, Ding-Wei

“…BackgroundDual blockade of immune checkpoint and angiogenesis is an effective strategy for multiple cancers. Camrelizumab is a monoclonal antibody against…”
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Construction of an immune‐related LncRNA signature with prognostic significance for bladder cancer by Luo, Wen‐Jie, Tian, Xi, Xu, Wen‐Hao, Qu, Yuan‐Yuan, Zhu, Wen‐Kai, Wu, Jie, Ma, Chun‐Guang, Zhang, Hai‐Liang, Ye, Ding‐Wei, Zhu, Yi‐Ping

“…Bladder cancer (BLCA) is one of the most common urological cancer with increasing cases and deaths every year. In the present study, we aim to construct an…”
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Identification of prognostic and therapeutic biomarkers in type 2 papillary renal cell carcinoma by Wang, Yue, Tian, Xi, Zhu, Shu-Xuan, Xu, Wen-Hao, Anwaier, Aihetaimujiang, Su, Jia-Qi, Gan, Hua-Lei, Qu, Yuan-Yuan, Zhao, Jian-Yuan, Zhang, Hai-Liang, Ye, Ding-Wei

“…Papillary renal cell carcinoma (PRCC) can be divided into type 1 (PRCC1) and type 2 (PRCC2) and PRCC2 share a more invasive phenotype and worse prognosis. This…”
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A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion by Xia, Pengyan, Wang, Shuo, Ye, Buqing, Du, Ying, Li, Chong, Xiong, Zhen, Qu, Yuan, Fan, Zusen

“…Disrupting the balance between self-renewal and differentiation of hematopoietic stem cells (HSCs) leads to bone marrow failure or hematologic malignancy…”
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Colonic Lysine Homocysteinylation Induced by High-Fat Diet Suppresses DNA Damage Repair by Wang, Dan, Zhao, Rui, Qu, Yuan-Yuan, Mei, Xin-Yu, Zhang, Xuan, Zhou, Qian, Li, Yang, Yang, Shao-Bo, Zuo, Zhi-Gui, Chen, Yi-Ming, Lin, Yan, Xu, Wei, Chen, Chao, Zhao, Shi-Min, Zhao, Jian-Yuan

“…Colorectal cancer (CRC) onset is profoundly affected by Western diet. Here, we report that high-fat (HF) diet-induced, organ-specific colonic lysine…”
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Reduced Expression of the Extracellular Calcium-Sensing Receptor (CaSR) Is Associated with Activation of the Renin-Angiotensin System (RAS) to Promote Vascular Remodeling in the Pathogenesis of Essential Hypertension by Qu, Yuan-Yuan, Hui, Jing, Wang, La-Mei, Tang, Na, Zhong, Hua, Liu, Yong-Min, Li, Zhen, Feng, Qian, He, Fang

“…The proliferation of vascular smooth muscle cells (VSMCs), remodeling of the vasculature, and the renin-angiotensin system (RAS) play important roles in the…”
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Prognostic implications of Aquaporin 9 expression in clear cell renal cell carcinoma by Xu, Wen-Hao, Shi, Shen-Nan, Xu, Yue, Wang, Jun, Wang, Hong-Kai, Cao, Da-Long, Shi, Guo-Hai, Qu, Yuan-Yuan, Zhang, Hai-Liang, Ye, Ding-Wei

“…Growing evidence has demonstrated immune reactivity as a confirmed important carcinogenesis and therapy efficacy for clear cell renal cell carcinoma (ccRCC)…”
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Decreased SPTLC1 expression predicts worse outcomes in ccRCC patients by Zhu, Wen‐Kai, Xu, Wen‐Hao, Wang, Jun, Huang, Yong‐Qiang, Abudurexiti, Mierxiati, Qu, Yuan‐Yuan, Zhu, Yi‐Ping, Zhang, Hai‐Liang, Ye, Ding‐Wei

“…Objective Serine palmitoyltransferase, long chain base subunit 1 (SPTLC1) catalyzes the first step in sphingolipid synthesis and has been implicated in the…”
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Nimotuzumab enhances the radiosensitivity of cancer cells in vitro by inhibiting radiation-induced DNA damage repair by Qu, Yuan-yuan, Hu, Song-liu, Xu, Xiang-ying, Wang, Rui-zhi, Yu, Hong-yang, Xu, Jian-yu, Chen, Lin, Dong, Guang-lu

“…Nimotuzumab is a humanized IgG1 monoclonal antibody specifically targeting EGFR. In this study, we aimed to investigate the molecular mechanisms of nimotuzumab…”
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Evaluation of clinicopathological profiles and development of a risk model in renal epithelioid angiomyolipoma patients: a large-scale retrospective cohort study by Anwaier, Aihetaimujiang, Xu, Wen-Hao, Tian, Xi, Ding, Tao, Su, Jia-Qi, Wang, Yue, Qu, Yuan-Yuan, Zhang, Hai-Liang, Ye, Ding-Wei

“…Abstract Background To identify the malignant potential and prognostic indicators of renal epithelioid angiomyolipoma (eAML), clinicopathological and molecular…”
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Prostate cancer in East Asia: evolving trend over the last decade by Zhu, Yao, Wang, Hong-Kai, Qu, Yuan-Yuan, Ye, Ding-Wei

“…Prostate cancer is now becoming an emerging health priority in East Asia. Most of our current knowledge on Prostate cancer has been generated from studies…”
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Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation by Wang, Shuo, Xia, Pengyan, Chen, Yi, Qu, Yuan, Xiong, Zhen, Ye, Buqing, Du, Ying, Tian, Yong, Yin, Zhinan, Xu, Zhiheng, Fan, Zusen

“…An emerging family of innate lymphoid cells (termed ILCs) has an essential role in the initiation and regulation of inflammation. However, it is still unclear…”
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