Search Results - "Qu, Yajin"

From SARS to MERS, Thrusting Coronaviruses into the Spotlight by Song, Zhiqi, Xu, Yanfeng, Bao, Linlin, Zhang, Ling, Yu, Pin, Qu, Yajin, Zhu, Hua, Zhao, Wenjie, Han, Yunlin, Qin, Chuan

“…Coronaviruses (CoVs) have formerly been regarded as relatively harmless respiratory pathogens to humans. However, two outbreaks of severe respiratory tract…”
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Ocular conjunctival inoculation of SARS-CoV-2 can cause mild COVID-19 in rhesus macaques by Deng, Wei, Bao, Linlin, Gao, Hong, Xiang, Zhiguang, Qu, Yajin, Song, Zhiqi, Gong, Shuran, Liu, Jiayi, Liu, Jiangning, Yu, Pin, Qi, Feifei, Xu, Yanfeng, Li, Fengli, Xiao, Chong, Lv, Qi, Xue, Jing, Wei, Qiang, Liu, Mingya, Wang, Guanpeng, Wang, Shunyi, Yu, Haisheng, Chen, Ting, Liu, Xing, Zhao, Wenjie, Han, Yunlin, Qin, Chuan

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly transmitted through the respiratory route, but potential extra-respiratory routes of…”
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Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques by Deng, Wei, Bao, Linlin, Liu, Jiangning, Xiao, Chong, Liu, Jiayi, Xue, Jing, Lv, Qi, Qi, Feifei, Gao, Hong, Yu, Pin, Xu, Yanfeng, Qu, Yajin, Li, Fengdi, Xiang, Zhiguang, Yu, Haisheng, Gong, Shuran, Liu, Mingya, Wang, Guanpeng, Wang, Shunyi, Song, Zhiqi, Liu, Ying, Zhao, Wenjie, Han, Yunlin, Zhao, Linna, Liu, Xing, Wei, Qiang, Qin, Chuan

“…Coronavirus disease 2019 (COVID-19), which is caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global…”
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The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice by Bao, Linlin, Deng, Wei, Huang, Baoying, Gao, Hong, Liu, Jiangning, Ren, Lili, Wei, Qiang, Yu, Pin, Xu, Yanfeng, Qi, Feifei, Qu, Yajin, Li, Fengdi, Lv, Qi, Wang, Wenling, Xue, Jing, Gong, Shuran, Liu, Mingya, Wang, Guanpeng, Wang, Shunyi, Song, Zhiqi, Zhao, Linna, Liu, Peipei, Zhao, Li, Ye, Fei, Wang, Huijuan, Zhou, Weimin, Zhu, Na, Zhen, Wei, Yu, Haisheng, Zhang, Xiaojuan, Guo, Li, Chen, Lan, Wang, Conghui, Wang, Ying, Wang, Xinming, Xiao, Yan, Sun, Qiangming, Liu, Hongqi, Zhu, Fanli, Ma, Chunxia, Yan, Lingmei, Yang, Mengli, Han, Jun, Xu, Wenbo, Tan, Wenjie, Peng, Xiaozhong, Jin, Qi, Wu, Guizhen, Qin, Chuan

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19), which has become a public health emergency of…”
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Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy by Du, Shuo, Cao, Yunlong, Zhu, Qinyu, Yu, Pin, Qi, Feifei, Wang, Guopeng, Du, Xiaoxia, Bao, Linlin, Deng, Wei, Zhu, Hua, Liu, Jiangning, Nie, Jianhui, Zheng, Yinghui, Liang, Haoyu, Liu, Ruixue, Gong, Shuran, Xu, Hua, Yisimayi, Ayijiang, Lv, Qi, Wang, Bo, He, Runsheng, Han, Yunlin, Zhao, Wenjie, Bai, Yali, Qu, Yajin, Gao, Xiang, Ji, Chenggong, Wang, Qisheng, Gao, Ning, Huang, Weijin, Wang, Youchun, Xie, X. Sunney, Su, Xiao-dong, Xiao, Junyu, Qin, Chuan

“…Understanding how potent neutralizing antibodies (NAbs) inhibit SARS-CoV-2 is critical for effective therapeutic development. We previously described BD-368-2,…”
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Distinct uptake, amplification, and release of SARS-CoV-2 by M1 and M2 alveolar macrophages by Lv, Jiadi, Wang, Zhenfeng, Qu, Yajin, Zhu, Hua, Zhu, Qiangqiang, Tong, Wei, Bao, Linlin, Lv, Qi, Cong, Ji, Li, Dan, Deng, Wei, Yu, Pin, Song, Jiangping, Tong, Wei-Min, Liu, Jiangning, Liu, Yuying, Qin, Chuan, Huang, Bo

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades the alveoli, where abundant alveolar macrophages (AMs) reside. How AMs respond to…”
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Brain Derived Exosomes Are a Double-Edged Sword in Alzheimer's Disease by Song, Zhiqi, Xu, Yanfeng, Deng, Wei, Zhang, Ling, Zhu, Hua, Yu, Pin, Qu, Yajin, Zhao, Wenjie, Han, Yunlin, Qin, Chuan

“…Brain derived exosomes (BDEs) are extracellular nanovesicles that are collectively released by all cell lineages of the central nervous system and contain…”
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Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 via Close Contact and Respiratory Droplets Among Human Angiotensin-Converting Enzyme 2 Mice by Bao, Linlin, Gao, Hong, Deng, Wei, Lv, Qi, Yu, Haisheng, Liu, Mingya, Yu, Pin, Liu, Jiangning, Qu, Yajin, Gong, Shuran, Lin, Kaili, Qi, Feifei, Xu, Yanfeng, Li, Fengli, Xiao, Chong, Xue, Jing, Song, Zhiqi, Xiang, Zhiguang, Wang, Guanpeng, Wang, Shunyi, Liu, Xing, Zhao, Wenjie, Han, Yunlin, Wei, Qiang, Qin, Chuan

“…Abstract We simulated 3 transmission modes, including close-contact, respiratory droplets and aerosol routes, in the laboratory. Severe acute respiratory…”
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Age‐related rhesus macaque models of COVID‐19 by Yu, Pin, Qi, Feifei, Xu, Yanfeng, Li, Fengdi, Liu, Peipei, Liu, Jiayi, Bao, Linlin, Deng, Wei, Gao, Hong, Xiang, Zhiguang, Xiao, Chong, Lv, Qi, Gong, Shuran, Liu, Jiangning, Song, Zhiqi, Qu, Yajin, Xue, Jing, Wei, Qiang, Liu, Mingya, Wang, Guanpeng, Wang, Shunyi, Yu, Haisheng, Liu, Xing, Huang, Baoying, Wang, Wenling, Zhao, Li, Wang, Huijuan, Ye, Fei, Zhou, Weimin, Zhen, Wei, Han, Jun, Wu, Guizhen, Jin, Qi, Wang, Jianwei, Tan, Wenjie, Qin, Chuan

“…Background Since December 2019, an outbreak of the Corona Virus disease 2019 (COVID‐19) caused by severe acute respiratory syndrome coronavirus (SARS‐CoV‐2) in…”
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Sequential infection with H1N1 and SARS-CoV-2 aggravated COVID-19 pathogenesis in a mammalian model, and co-vaccination as an effective method of prevention of COVID-19 and influenza by Bao, Linlin, Deng, Wei, Qi, Feifei, Lv, Qi, Song, Zhiqi, Liu, Jiangning, Gao, Hong, Wei, Qiang, Yu, Pin, Xu, Yanfeng, Qu, Yajin, Li, Fengdi, Xue, Jing, Gong, Shuran, Liu, Mingya, Wang, Guanpeng, Wang, Shunyi, Zhao, Binbin, Cong, Bin, Qin, Chuan

“…Influenza A virus may circulate simultaneously with the SARS-CoV-2 virus, leading to more serious respiratory diseases during this winter. However, the…”
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SARS-CoV-2 treatment effects induced by ACE2-expressing microparticles are explained by the oxidized cholesterol-increased endosomal pH of alveolar macrophages by Wang, Zhenfeng, Lv, Jiadi, Yu, Pin, Qu, Yajin, Zhou, Yabo, Zhou, Li, Zhu, Qiangqiang, Li, Shunshun, Song, Jiangping, Deng, Wei, Gao, Ran, Liu, Yuying, Liu, Jiangning, Tong, Wei-Min, Qin, Chuan, Huang, Bo

“…Exploring the cross-talk between the immune system and advanced biomaterials to treat SARS-CoV-2 infection is a promising strategy. Here, we show that…”
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Modulation of Autophagy-Lysosome Axis by African Swine Fever Virus and Its Encoded Protein pEP153R by Bai, Si-Yu, Weng, Wenlian, Wang, Hua, Cui, Zhiying, Wu, Jiajun, Qu, Yajin, Hao, Yuxin, Gao, Peng, Zhang, Yongning, Zhou, Lei, Ge, Xinna, Guo, Xin, Han, Jun, Yang, Hanchun

“…The autophagy-lysosome axis is an evolutionarily conserved intracellular degradation pathway which constitutes an important component of host innate immunity…”
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Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer's Disease in 5XFAD Mouse Model by Song, Zhiqi, Xu, Yanfeng, Zhang, Ling, Zhou, Li, Zhang, Yu, Han, Yunlin, Li, Xianglei, Yu, Pin, Qu, Yajin, Zhao, Wenjie, Qin, Chuan

“…Alzheimer's disease (AD) is an incurable neurodegenerative disease characterized by irreversible progressive cognitive deficits. Identification of candidate…”
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Outbreak of variant pseudorabies virus in Bartha-K61–vaccinated piglets in central Shandong Province, China by Hu, Dongfang, Zhang, Zhendong, Lv, Lin, Xiao, Yihong, Qu, Yajin, Ma, Haiying, Niu, Yujuan, Wang, Guangwen, Liu, Sidang

“…An epidemic that mainly endangered 3–7-day-old piglets struck many farms in Shandong Province, China in 2013 and caused heavy losses. To identify the…”
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The comprehensive diagnosis and prevention of duck plague in northwest Shandong province of China by Wang, Guangwen, Qu, Yajin, Wang, Fangkun, Hu, Dongfang, Liu, Litao, Li, Ning, Yue, Ruichao, Li, Chao, Liu, Sidang

“…Here, we report the first outbreak of duck plague (DP) confirmed in 4 tissue samples that were collected since August 2012 from the northwestern region of…”
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BNT162b2 Vaccine Encoding the SARS-CoV-2 P2 S Protects Transgenic hACE2 Mice against COVID-19 by Ji, Rui-Ru, Qu, Yajin, Zhu, Hua, Yang, Yumei, Vogel, Annette B, Sahin, Ugur, Qin, Chuan, Hui, Aimin

“…BNT162b2 is a highly efficacious mRNA vaccine approved to prevent COVID-19. This brief report describes the immunogenicity and anti-viral protective effect of…”
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Microarray microRNA profiling of urinary exosomes in a 5XFAD mouse model of Alzheimer’s disease by Song, Zhiqi, Qu, Yajin, Xu, Yanfeng, Zhang, Ling, Zhou, Li, Han, Yunlin, Zhao, Wenjie, Yu, Pin, Zhang, Yu, Li, Xianglei, Qin, Chuan

“…Background Alzheimer's disease (AD) is an incurable and irreversible neurodegenerative disease, without a clear pathogenesis. Therefore, identification of…”
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SARS‐CoV‐2 infection aggravates chronic comorbidities of cardiovascular diseases and diabetes in mice by Ma, Yuanwu, Lu, Dan, Bao, Linlin, Qu, Yajin, Liu, Jiangning, Qi, Xiaolong, Yu, Lei, Zhang, Xu, Qi, Feifei, Lv, Qi, Liu, Yunpeng, Shi, Xudong, Sun, Caixian, Li, Jing, Wang, Jie, Han, Yunlin, Gao, Kai, Dong, Wei, Liu, Ning, Gao, Shan, Xue, Jing, Wei, Qiang, Pan, Sidan, Gao, Hong, Zhang, Lianfeng, Qin, Chuan

“…Background Cardiovascular diseases (CVDs) and diabetes mellitus (DM) are top two chronic comorbidities that increase the severity and mortality of COVID‐19…”
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A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity by Yang, Jingyun, Wang, Wei, Chen, Zimin, Lu, Shuaiyao, Yang, Fanli, Bi, Zhenfei, Bao, Linlin, Mo, Fei, Li, Xue, Huang, Yong, Hong, Weiqi, Yang, Yun, Zhao, Yuan, Ye, Fei, Lin, Sheng, Deng, Wei, Chen, Hua, Lei, Hong, Zhang, Ziqi, Luo, Min, Gao, Hong, Zheng, Yue, Gong, Yanqiu, Jiang, Xiaohua, Xu, Yanfeng, Lv, Qi, Li, Dan, Wang, Manni, Li, Fengdi, Wang, Shunyi, Wang, Guanpeng, Yu, Pin, Qu, Yajin, Yang, Li, Deng, Hongxin, Tong, Aiping, Li, Jiong, Wang, Zhenling, Yang, Jinliang, Shen, Guobo, Zhao, Zhiwei, Li, Yuhua, Luo, Jingwen, Liu, Hongqi, Yu, Wenhai, Yang, Mengli, Xu, Jingwen, Wang, Junbin, Li, Haiyan, Wang, Haixuan, Kuang, Dexuan, Lin, Panpan, Hu, Zhengtao, Guo, Wei, Cheng, Wei, He, Yanlin, Song, Xiangrong, Chen, Chong, Xue, Zhihong, Yao, Shaohua, Chen, Lu, Ma, Xuelei, Chen, Siyuan, Gou, Maling, Huang, Weijin, Wang, Youchun, Fan, Changfa, Tian, Zhixin, Shi, Ming, Wang, Fu-Sheng, Dai, Lunzhi, Wu, Min, Li, Gen, Wang, Guangyu, Peng, Yong, Qian, Zhiyong, Huang, Canhua, Lau, Johnson Yiu-Nam, Yang, Zhenglin, Wei, Yuquan, Cen, Xiaobo, Peng, Xiaozhong, Qin, Chuan, Zhang, Kang, Lu, Guangwen, Wei, Xiawei

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a respiratory disease called coronavirus disease 2019 (COVID-19), the spread of which has…”
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Riding apoptotic bodies for cell-cell transmission by African swine fever virus by Gao, Peng, Zhou, Lei, Wu, Jiajun, Weng, Wenlian, Wang, Hua, Ye, Miaomiao, Qu, Yajin, Hao, Yuxin, Zhang, Yongning, Ge, Xinna, Guo, Xin, Han, Jun, Yang, Hanchun

“…African swine fever virus (ASFV), a devastating pathogen to the worldwide swine industry, mainly targets macrophage/monocyte lineage, but how the virus enters…”
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