Search Results - "Qu, Fanqi"
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An Amphiphilic Dendrimer for Effective Delivery of Small Interfering RNA and Gene Silencing In Vitro and In Vivo
Published in Angewandte Chemie International Edition (20-08-2012)“…An amphiphilic dendrimer bearing a hydrophobic alkyl chain and hydrophilic poly(amidoamine) dendrons is able to combine the advantageous features of lipid and…”
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2
Mastering Dendrimer Self-Assembly for Efficient siRNA Delivery: From Conceptual Design to In Vivo Efficient Gene Silencing
Published in Small (Weinheim an der Bergstrasse, Germany) (01-07-2016)“…Self‐assembly is a fundamental concept and a powerful approach in molecular science. However, creating functional materials with the desired properties through…”
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3
Efficient Delivery of Sticky siRNA and Potent Gene Silencing in a Prostate Cancer Model Using a Generation 5 Triethanolamine-Core PAMAM Dendrimer
Published in Molecular pharmaceutics (05-03-2012)“…Successful achievement of RNA interference in therapeutic applications requires safe and efficient vectors for siRNA delivery. In the present study, we…”
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4
Novel Triazole Ribonucleoside Down-Regulates Heat Shock Protein 27 and Induces Potent Anticancer Activity on Drug-Resistant Pancreatic Cancer
Published in Journal of medicinal chemistry (08-10-2009)“…A series of novel 3-arylethynyltriazolyl ribonucleosides were synthesized and assessed for their anticancer activity on the drug-resistant pancreatic cancer…”
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Discovery of Novel Arylethynyltriazole Ribonucleosides with Selective and Effective Antiviral and Antiproliferative Activity
Published in Journal of medicinal chemistry (26-02-2009)“…Novel ethynyltriazole ribonucleosides were synthesized using a simple and efficient two-step procedure involving Sonogashira coupling and subsequent…”
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6
Arylethynyltriazole acyclonucleosides inhibit hepatitis C virus replication
Published in Bioorganic & medicinal chemistry (01-06-2008)“…Novel ethynyltriazole acyclonucleosides were synthesized efficiently via a one-step Sonogashira reaction in aqueous solution and under microwave irradiation…”
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7
An Efficient Mixed-Ligand Pd Catalytic System to Promote CN Coupling for the Synthesis of N-Arylaminotriazole Nucleosides
Published in Chemistry : a European journal (20-02-2012)“…Make it unique! A mixed‐ligand system of Pd/Synphos/Xantphos promotes effective CN coupling in the synthesis of various N‐arylaminotriazole and…”
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8
Synthesis of bitriazolyl nucleosides and unexpectedly different reactivity of azidotriazole nucleoside isomers in the Huisgen reaction
Published in Organic & biomolecular chemistry (01-01-2007)“…Novel bitriazolyl nucleosides were synthesized via the Huisgen reaction, starting with 3-azidotriazole nucleoside (1). Surprisingly, its isomer,…”
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9
Direct synthesis of 5-aryltriazole acyclonucleosides via Suzuki coupling in aqueous solution
Published in Tetrahedron letters (26-03-2007)“…5-Aryltriazole acyclonucleosides with various aromatic groups on the triazole ring were synthesized via the Suzuki coupling reaction in aqueous solution and…”
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10
A novel arylethynyltriazole acyclonucleoside inhibits proliferation of drug-resistant pancreatic cancer cells
Published in Bioorganic & medicinal chemistry letters (15-10-2010)“…A novel ethynyltriazole acyclonucleoside showed superior antiproliferative effect to and different mechanism from gemcitabine, the current reference treatment…”
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11
N-Aryltriazole ribonucleosides with potent antiproliferative activity against drug-resistant pancreatic cancer
Published in Bioorganic & medicinal chemistry letters (15-04-2010)“…Novel N-aryltriazole nucleosides were synthesized via Cu-mediated C–N cross-coupling reaction starting with 3-aminotriazole ribonucleoside and various boronic…”
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12
Discovery of bitriazolyl compounds as novel antiviral candidates for combating the tobacco mosaic virus
Published in Bioorganic & medicinal chemistry letters (15-05-2006)“…Bitriazolyl compounds have been discovered to show promising antiviral activity against tobacco mosaic virus and may constitute interesting leads for the…”
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13
Bitriazolyl acyclonucleosides synthesized via Huisgen reaction using internal alkynes show antiviral activity against tobacco mosaic virus
Published in Bioorganic & medicinal chemistry letters (01-01-2011)“…A family of novel bitriazolyl acyclonucleosides were synthesized via the Huisgen reaction by addition of NaN3 onto the triazole nucleosides bearing internal…”
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14
S-Aryltriazole acyclonucleosides: Synthesis and biological evaluation against hepatitis C virus
Published in Bioorganic & medicinal chemistry letters (15-06-2010)“…Novel S-aryltriazole acyclonucleosides were designed as structural analogs based on the previously identified antiviral aryltriazole acyclonucleosides in our…”
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15
2-Chloro-4-iodoaniline
Published in Acta crystallographica. Section E, Structure reports online (01-12-2008)“…The title dihaloaniline, C6H5ClIN, shows no significant hydrogen bonds nor the commonly observed I...I interactions in the crystal structure, although an amino…”
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16
4-Nitrophenyl methacrylate
Published in Acta crystallographica. Section E, Structure reports online (01-09-2008)“…The title compound, C 10 H 9 NO 4 , was obtained serendipitously during the preparation of benzyl cyclohexylcarbamate. The molecule consists of two…”
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4-Nitrophenyl N -phenylcarbamate
Published in Acta crystallographica. Section E, Structure reports online (01-02-2008)“…The title compound, C13H10N2O4, was synthesized as an intermediate for the preparation of ureas. The two aromatic rings are twisted about the central carbamate…”
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18
Integrated municipal wastewater treatment and lipid accumulation by a self-flocculating/floating microalga Limnothrix sp
Published in Bioresource technology (01-02-2024)“…[Display omitted] •A novel self-flocculating blue-green microalga Limnothrix sp. was isolated.•High self-flocculating efficiency (>90 %) was obtained in…”
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Enhancement of productivity of Chlorella pyrenoidosa lipids for biodiesel using co-culture with ammonia-oxidizing bacteria in municipal wastewater
Published in Renewable energy (01-05-2020)“…As one of the most promising renewable energy, microalgal biodiesel has been widely studied worldwide. However, the low-efficiency of conventional microalgae…”
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20
Promoting siRNA delivery via enhanced cellular uptake using an arginine-decorated amphiphilic dendrimer
Published in Nanoscale (07-03-2015)“…RNA interference (RNAi) with small interfering RNA (siRNA) is expected to offer an attractive means to specifically and efficiently silence disease-associated…”
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