Search Results - "Qu, Aidong"

Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies by Yi, Chunyan, Sun, Xiaoyu, Ye, Jing, Ding, Longfei, Liu, Meiqin, Yang, Zhuo, Lu, Xiao, Zhang, Yaguang, Ma, Liyang, Gu, Wangpeng, Qu, Aidong, Xu, Jianqing, Shi, Zhengli, Ling, Zhiyang, Sun, Bing

“…Coronavirus disease 2019 (COVID-19), caused by the novel human coronavirus SARS-CoV-2, is currently a major threat to public health worldwide. The viral spike…”
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Comprehensive mapping of binding hot spots of SARS-CoV-2 RBD-specific neutralizing antibodies for tracking immune escape variants by Yi, Chunyan, Sun, Xiaoyu, Lin, Yixiao, Gu, Chenjian, Ding, Longfei, Lu, Xiao, Yang, Zhuo, Zhang, Yaguang, Ma, Liyan, Gu, Wangpeng, Qu, Aidong, Zhou, Xu, Li, Xiuling, Xu, Jianqing, Ling, Zhiyang, Xie, Youhua, Lu, Hongzhou, Sun, Bing

“…Abstract Background The receptor-binding domain (RBD) variants of SARS-CoV-2 could impair antibody-mediated neutralization of the virus by host immunity; thus,…”
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The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin by Qu, Aidong, Leahy, Daniel J

“…Background The integrin family of cell-surface receptors mediates a wide variety of cell–cell and cell–extracellular matrix interactions. Integrin–ligand…”
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TFAB002s, novel CD20-targeting T cell-dependent bispecific Fab-FabCH3 antibodies, exhibit potent antitumor efficacy against malignant B-cell lymphoma by Li, Qinghong, Zhang, Kunming, Yu, Yao, Yu, Zeng, Xu, Jingyi, Shen, Wenyan, Zhang, Lin, Qu, Aidong, Liang, Hongyuan

“…B-cell lymphoma, clinically, comprises a heterogeneous group of malignancies that encompass various subtypes. CD20 is an optimal target for therapeutic…”
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Outcome benefits of bevacizumab biosimilar (SIBP04) combined with carboplatin and paclitaxel in advanced non-squamous non-small-cell lung cancer patients with EGFR mutation: subgroup analysis of a prospective, randomized phase III clinical trial by Qu, Aidong, Zhang, Shiying, Zou, Hongxia, Li, Sixiu, Chen, Dandan, Zhang, Yaowen, Li, Songsong, Zhang, Huijun, Yang, Ji, Yang, Yunkai, Huang, Yubao, Li, Xiuling, Zhang, Yuntao

“…Purpose SIBP04 is a bevacizumab biosimilar, and bevacizumab combined with carboplatin and paclitaxel in advanced non-squamous non-small-cell lung cancer…”
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Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2 by Sun, Xiaoyu, Yi, Chunyan, Zhu, Yuanfei, Ding, Longfei, Xia, Shuai, Chen, Xingchen, Liu, Mu, Gu, Chenjian, Lu, Xiao, Fu, Yadong, Chen, Shuangfeng, Zhang, Tianlong, Zhang, Yaguang, Yang, Zhuo, Ma, Liyan, Gu, Wangpeng, Hu, Gaowei, Du, Shujuan, Yan, Renhong, Fu, Weihui, Yuan, Songhua, Qiu, Chenli, Zhao, Chen, Zhang, Xiaoyan, He, Yonghui, Qu, Aidong, Zhou, Xu, Li, Xiuling, Wong, Gary, Deng, Qiang, Zhou, Qiang, Lu, Hongzhou, Ling, Zhiyang, Ding, Jianping, Lu, Lu, Xu, Jianqing, Xie, Youhua, Sun, Bing

“…Frequent outbreaks of coronaviruses underscore the need for antivirals and vaccines that can counter a broad range of coronavirus types. We isolated a human…”
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Modified response evaluation criteria in solid tumors: A better response evaluation criteria for patients with non-squamous non-small cell lung cancer after bevacizumab treatment by Huang, Yubao, Yang, Yunkai, Qu, Aidong, Li, Sixiu, Chen, Dandan, Zou, Hongxia, Li, Songsong, Zhang, Yaowen, Zhuang, Wei, Su, Jing, Zhou, Xu, Zhang, Yuntao

“…Cavitation of lesions is common in non-squamous non-small cell lung cancer (non-squamous-NSCLC) patients treated with vascular endothelial growth factor…”
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Abstract 6435: BCG008, a human Siglec-15 blocking antibody, displays potent anti-tumor activity in Siglec-15-humanized mice by Yang, Yongfei, Qu, Aidong, Yao, Fengping, Song, Pan, Liang, Hongyuan, Tian, Maopeng, Yang, Fang, Yu, Zhaoxue, Zhou, Xu, Li, Xiuling

“…Abstract Sialic acid-binding Ig-like lectin 15, or Siglec-15, is identified as a critical immune suppressor. Siglec-15 expression is normally limited to…”
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Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha sub(L) beta 2) integrin by Qu, Aidong, Leahy, D J

“…We report the 1.8-angstrom crystal structure of the CD11a I-domain with bound manganese ion. The CD11a I-domain contains binding sites for intercellular…”
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Crystal Structure of the I-Domain from the CD11a/CD18 (LFA-1, αLβ2) Integrin by Qu, Aidong, Leahy, Daniel J.

“…We report the 1.8-Å crystal structure of the CD11a I-domain with bound manganese ion. The CD11a I-domain contains binding sites for intercellular adhesion…”
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