Search Results - "Qu, A"

Applications of Connectivity Map in drug discovery and development by Qu, Xiaoyan A., Rajpal, Deepak K.

“…► CMap approach offers alternative ways to drug discovery. ► CMap enables efficient hypothesis generation for mechanism understanding and drug repurposing. ►…”
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Individualized dynamic latent factor model for multi-resolutional data with application to mobile health by Zhang, J, Xue, F, Xu, Q, Lee, J, Qu, A

“…Summary Mobile health has emerged as a major success for tracking individual health status, due to the popularity and power of smartphones and wearable…”
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Systematic prediction of drug combinations based on clinical side-effects by Huang, Hui, Zhang, Ping, Qu, Xiaoyan A., Sanseau, Philippe, Yang, Lun

“…Drug co-prescription (or drug combination) is a therapeutic strategy widely used as it may improve efficacy and reduce side-effect (SE). Since it is…”
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Circulating miR‐210 as a diagnostic and prognostic biomarker for colorectal cancer by Wang, W., Qu, A., Liu, W., Liu, Y., Zheng, G., Du, L., Zhang, X., Yang, Y., Wang, C., Chen, X.

“…microRNA‐210 (miR‐210), the master hypoxamir, is overexpressed and generally exhibits oncogenic properties in most human solid tumours, including colorectal…”
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Room temperature strain-induced Landau levels in graphene on a wafer-scale platform by Nigge, P, Qu, A C, Lantagne-Hurtubise, É, Mårsell, E, Link, S, Tom, G, Zonno, M, Michiardi, M, Schneider, M, Zhdanovich, S, Levy, G, Starke, U, Gutiérrez, C, Bonn, D, Burke, S A, Franz, M, Damascelli, A

“…Graphene is a powerful playground for studying a plethora of quantum phenomena. One of the remarkable properties of graphene arises when it is strained in…”
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Characterization of a novel capsaicin/heat ongoing pain model by Price, R.C., Gandhi, W., Nadeau, C., Tarnavskiy, R., Qu, A., Fahey, E., Stone, L., Schweinhardt, P.

“…Background Human experimental pain models provide an important translational link between pre‐clinical models and clinical pain. Using topical capsaicin and…”
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Illuminating the biosynthesis pathway genes involved in bioactive specific monoterpene glycosides in Paeonia veitchii Lynch by a combination of sequencing platforms by Zhang, Shaoshan, Qu-Bie, Jun-Zhang, Feng, Ming-Kang, Qu-Bie, A-Xiang, Huang, Yanfei, Zhang, Zhi-Feng, Yan, Xin-Jia, Liu, Yuan

“…Paeonia veitchii Lynch, a well-known herb from the Qinghai-Tibet Plateau south of the Himalayas, can synthesize specific monoterpene glycosides (PMGs) with…”
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Ubiquitous defect-induced density wave instability in monolayer graphene by Qu, A C, Nigge, P, Link, S, Levy, G, Michiardi, M, Spandar, P L, Matthé, T, Schneider, M, Zhdanovich, S, Starke, U, Gutiérrez, C, Damascelli, A

“…Quantum materials are notoriously sensitive to their environments, where small perturbations can tip a system toward one of several competing ground states…”
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Expression level of miRNA-210-3p in cervical cancer and its prognostic potential by Shao, M-X, Qu, A-Z, Wang, Y-Q, Zhong, Y-Y

“…The purpose of this study was to detect the expression level of microRNA-210-3p (miRNA-210-3p) in cervical cancer (CC) tissues and its clinical significance…”
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Sex differences in global mRNA content of human skeletal muscle by Maher, Amy C, Fu, Minghua H, Isfort, Robert J, Varbanov, Alex R, Qu, Xiaoyan A, Tarnopolsky, Mark A

“…Women oxidize more fat as compared to men during endurance exercise and several groups have shown that the mRNA content of selected genes related to fat…”
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EP-1328: Phase I study of weekly PTX/DDP, and postoperative radiotherapy for early cervical cancer in Chinese by Zhu, L, Jiang, W, Tian, S, Qu, A, Wang, H, Li, X, Wang, J

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Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress by Qin, Pu, Arabacilar, Pelin, Bernard, Roberta E, Bao, Weike, Olzinski, Alan R, Guo, Yuanjun, Lal, Hind, Eisennagel, Stephen H, Platchek, Michael C, Xie, Wensheng, Del Rosario, Julius, Nayal, Mohamad, Lu, Quinn, Roethke, Theresa, Schnackenberg, Christine G, Wright, Fe, Quaile, Michael P, Halsey, Wendy S, Hughes, Ashley M, Sathe, Ganesh M, Livi, George P, Kirkpatrick, Robert B, Qu, Xiaoyan A, Rajpal, Deepak K, Faelth Savitski, Maria, Bantscheff, Marcus, Joberty, Gerard, Bergamini, Giovanna, Force, Thomas L, Gatto, Jr, Gregory J, Hu, Erding, Willette, Robert N

“…The amino acid response (AAR) is an evolutionarily conserved protective mechanism activated by amino acid deficiency through a key kinase, general control…”
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On the Destabilization of Metastable Solid \( pound sterling \) He by Souris, F, Qu, A, Dupont-Roc, J, Grucker, J, Jacquier, Ph

“…Recently, a metastable state of solid \( pound sterling \) He has been produced by locally lowering the density of the solid below the melting density using a…”
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EP-1325: Phase I/II study of weekly cisplatin plus paclitaxel and radiotherapy for primary cervical cancer by Zhu, L, Jiang, W, Tian, S, Qu, A, Wang, H, Li, X, Liao, A, Jiang, Y, Wang, J

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EP-1332: Clinical results of Nimotuzumab Plus DDP and concurrent radiotherapy for primary cervix cancer by Zhu, L, Tian, S, Qu, A, Wang, H, Li, X, Jiang, Y, Sun, H, Lin, L, Wang, J

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Improving generalised estimating equations using quadratic inference functions by Qu, Annie, Lindsay, Bruce G., Li, Bing

“…Generalised estimating equations enable one to estimate regression parameters consistently in longitudinal data analysis even when the correlation structure is…”
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Incorporating Correlation for Multivariate Failure Time Data When Cluster Size Is Large by Xue, L., Wang, L., Qu, A.

“…We propose a new estimation method for multivariate failure time data using the quadratic inference function (QIF) approach. The proposed method efficiently…”
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Crystal Structure of the I-Domain from the CD11a/CD18 (LFA-1, αLβ2) Integrin by Qu, Aidong, Leahy, Daniel J.

“…We report the 1.8-Å crystal structure of the CD11a I-domain with bound manganese ion. The CD11a I-domain contains binding sites for intercellular adhesion…”
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Simultaneous stimulation of Fas-mediated apoptosis and blockade of costimulation prevent autoimmune diabetes in mice induced by multiple low-dose streptozotocin by JIN, Y, QU, A, WANG, G. M, HAO, J, GAO, X, XIE, S

“…Type I diabetes is the result of a selective destruction of insulin-producing beta cells in pancreatic islets by autoreactive T cells. Depletion of…”
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Assessing robustness of generalised estimating equations and quadratic inference functions by Qu, Annie, Song, Peter X.‐K.

“…In the presence of data contamination or outliers, some empirical studies have indicated that the two methods of generalised estimating equations and quadratic…”
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