Search Results - "Qiushu Chen"

Turbidimetric inhibition immunoassay revisited to enhance its sensitivity via an optofluidic laser by Yang, Xi, Shu, Wenxiong, Wang, Yanqiong, Gong, Yuan, Gong, Chaoyang, Chen, Qiushu, Tan, Xiaotian, Peng, Gang-Ding, Fan, Xudong, Rao, Yun-Jiang

“…Turbidimetric inhibition immunoassay (TIIA) is a classic immunodiagnostic method that has been extensively used for biomarker detection. However, the low…”
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On-chip, high-sensitivity temperature sensors based on dye-doped solid-state polymer microring lasers by Wan, Lei, Chandrahalim, Hengky, Chen, Cong, Chen, Qiushu, Mei, Ting, Oki, Yuji, Nishimura, Naoya, Guo, L. Jay, Fan, Xudong

“…We developed a chip-scale temperature sensor with a high sensitivity of 228.6 pm/°C based on a rhodamine 6G (R6G)-doped SU-8 whispering gallery mode microring…”
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Optofluidic FRET Lasers and Their Applications in Novel Photonic Devices and Biochemical Sensing by Aas, Mehdi, Qiushu Chen, Jonas, Alexandr, Kiraz, Alper, Xudong Fan

“…Incorporating fluorescence resonance energy transfer (FRET) into a laser cavity can increase the sensitivity of FRET-based biochemical sensors due to the…”
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Laser-emission imaging of nuclear biomarkers for high-contrast cancer screening and immunodiagnosis by Chen, Yu-Cheng, Tan, Xiaotian, Sun, Qihan, Chen, Qiushu, Wang, Wenjie, Fan, Xudong

“…Detection of nuclear biomarkers, such as nucleic acids and nuclear proteins, is critical for early-stage cancer diagnosis and prognosis. Conventional methods…”
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Refractive index sensing based on semiconductor nanowire lasers by Wu, Xiaoqin, Chen, Qiushu, Xu, Peizhen, Tong, Limin, Fan, Xudong

“…We demonstrate a refractive index (RI) sensor based on semiconductor nanowire lasers. It is shown that the TE01 mode is responsible for lasing and sensing with…”
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Design of an ellipsoidal mirror assisted oblique plane microscopy by Liu, Yuzhe, Chen, Qiushu, Fei, Yiyan, Mi, Lan, Ma, Jiong

“…Using one objective for excitation and detection simultaneously, oblique plane microscopy (OPM) provides a mounting-friendly approach for optical sectioning…”
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Rapid and precise multifocal cutaneous tumor margin assessment using fluorescence lifetime detection and machine learning by Su, Wenhua, Zheng, Dachao, Zhou, Jiacheng, Chen, Qiushu, Chen, Liwen, Yang, Yuwei, Fei, Yiyan, Yao, Haijun, Ma, Jiong, Mi, Lan

“…The precise determination of surgical margins is essential for the management of multifocal cutaneous cancers, including extramammary Paget’s disease. This…”
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Evaluating Differentiation Status of Mesenchymal Stem Cells by Label-Free Microscopy System and Machine Learning by Kong, Yawei, Ao, Jianpeng, Chen, Qiushu, Su, Wenhua, Zhao, Yinping, Fei, Yiyan, Ma, Jiong, Ji, Minbiao, Mi, Lan

“…Mesenchymal stem cells (MSCs) play a crucial role in tissue engineering, as their differentiation status directly affects the quality of the final cultured…”
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A digital microfluidic single-cell manipulation system optimized by extending-depth-of-field device by Chen, Qiushu, Meng, Qi, Liu, Yuzhe, Long, Xiangan, Kong, Yawei, Yao, Longfang, Chen, Liwen, Wu, Chuanyong, Chu, Kaiqin, Mi, Lan, Ma, Jiong

“…Microfluidic systems have been widely utilized in high-throughput biology analysis, but the difficulties in liquid manipulation and cell cultivation limit its…”
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Highly sensitive optofluidic FRET lasers with genetically encoded fluorescent protein pairs by Qiushu Chen, Xingwang Zhang, Sun, Yuze, Ritt, Mike, Sivaramakrishnan, Sivaraj, Xudong Fan

“…We achieved optofluidic FRET lasers using genetically encoded fluorescent protein pairs linked by length-tunable peptides. 10-fold enhancement in the FRET…”
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Optofluidic FRET lasers using aqueous quantum dots as donors by Chen, Qiushu, Kiraz, Alper, Fan, Xudong

“…An optofluidic FRET (fluorescence resonance energy transfer) laser is formed by putting FRET pairs inside a microcavity acting as a gain medium. This…”
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Digital DNA detection based on a compact optofluidic laser with ultra-low sample consumption by Lee, Wonsuk, Chen, Qiushu, Fan, Xudong, Yoon, Dong Ki

“…DNA lasers self-amplify optical signals from a DNA analyte as well as thermodynamic differences between sequences, allowing quasi-digital DNA detection…”
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Optofluidic lasers with a single molecular layer of gain by Chen, Qiushu, Ritt, Michael, Sivaramakrishnan, Sivaraj, Sun, Yuze, Fan, Xudong

“…We achieve optofluidic lasers with a single molecular layer of gain, in which green fluorescent protein, dye-labeled bovine serum albumin, and dye-labeled DNA,…”
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Lasing in blood by Chen, Yu-Cheng, Chen, Qiushu, Fan, Xudong

“…Indocyanine green (ICG) is the near-infrared dye approved by the U.S. Food and Drug Administration for clinical use. When injected in blood, ICG binds…”
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Gain controlled optofluidic lasers with self-assembled DNA tetrahedron by Qiushu Chen, Huajie Liu, Wonsuk Lee, Yuze Sun, Dan Zhu, Hao Pei, Chunhai Fan, Xudong Fan

“…Using self-assembled DNA tetrahedron, we were able to precisely control the gain in optofluidic FRET lasers. 3.8 times reduction in the lasing threshold and…”
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Domain adaptation of time series via contrastive learning with task-specific consistency by Wu, Tao, Chen, Qiushu, Zhao, Dongfang, Wang, Jinhua, Jiang, Linhua

“…Unsupervised domain adaptation (UDA) for time series analysis remains challenging due to the lack of labeled data in target domains. Existing methods rely…”
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Optofluidic laser for dual-mode sensitive biomolecular detection with a large dynamic range by Wu, Xiang, Oo, Maung Kyaw Khaing, Reddy, Karthik, Chen, Qiushu, Sun, Yuze, Fan, Xudong

“…Enzyme-linked immunosorbent assay (ELISA) is a powerful method for biomolecular analysis. The traditional ELISA employing light intensity as the sensing signal…”
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Highly sensitive fluorescent protein FRET detection using optofluidic lasers by Chen, Qiushu, Zhang, Xingwang, Sun, Yuze, Ritt, Michael, Sivaramakrishnan, Sivaraj, Fan, Xudong

“…We achieved optofluidic protein lasing using genetically encoded fluorescent protein FRET pairs linked by length-tunable peptides. Up to 25-fold reduction in…”
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Bio-inspired optofluidic lasers with luciferin by Wu, Xiang, Chen, Qiushu, Sun, Yuze, Fan, Xudong

“…The authors demonstrate a bio-inspired optofluidic laser with luciferin, a class of light-emitting compounds synthesized by many different organisms, as the…”
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CoNiCoNC tumor therapy by two-ways producing H2O2 to aggravate energy metabolism, chemokinetics, and ferroptosis by Sun, Mengmeng, Chen, Qiushu, Ren, Yingying, Zhuo, Yong, Xu, Shengyu, Rao, Hanbing, Wu, De, Feng, Bin, Wang, Yanying

“…[Display omitted] •CoNiCoNC can catalyze the self-supply of H2O2 from glucose and lactate, alleviating low H2O2 levels in the tumor TME.•CoNiCoNC has the…”
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