Search Results - "Qiu, Zhaojun"

Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors by Wang, Xiaoling, Wang, Yebo, Wu, Xiwei, Wang, Jinhui, Wang, Yingjia, Qiu, Zhaojun, Chang, Tammy, Huang, He, Lin, Ren-Jang, Yee, Jiing-Kuan

“…Off-target cleavage by CAS9 or TALEN genome editing tools is detected by integrase-defective lentiviral vectors. The utility of CRISPR-Cas9 and TALENs for…”
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RNF126 as a Biomarker of a Poor Prognosis in Invasive Breast Cancer and CHEK1 Inhibitor Efficacy in Breast Cancer Cells by Yang, Xiaosong, Pan, You, Qiu, Zhaojun, Du, Zhanwen, Zhang, Yao, Fa, Pengyan, Gorityala, Shashank, Ma, Shanhuai, Li, Shunqiang, Chen, Ceshi, Wang, Hongbing, Xu, Yan, Yan, Chunhong, Ruth, Keri, Ma, Zhefu, Zhang, Junran

“…(i) To investigate the expression of the E3 ligase, RNF126, in human invasive breast cancer and its links with breast cancer outcomes; and (ii) to test the…”
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The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity by Prasad, Chandra Bhushan, Oo, Adrian, Liu, Yujie, Qiu, Zhaojun, Zhong, Yaogang, Li, Na, Singh, Deepika, Xin, Xiwen, Cho, Young-Jae, Li, Zaibo, Zhang, Xiaoli, Yan, Chunhong, Zheng, Qingfei, Wang, Qi-En, Guo, Deliang, Kim, Baek, Zhang, Junran

“…Checkpoint kinase 1 (CHK1) is critical for cell survival under replication stress (RS). CHK1 inhibitors (CHK1i’s) in combination with chemotherapy have shown…”
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A Genome-Wide Pooled shRNA Screen Identifies PPP2R2A as a Predictive Biomarker for the Response to ATR and CHK1 Inhibitors by Qiu, Zhaojun, Fa, Pengyan, Liu, Tao, Prasad, Chandra B, Ma, Shanhuai, Hong, Zhipeng, Chan, Ernest R, Wang, Hongbing, Li, Zaibo, He, Kai, Wang, Qi-En, Williams, Terence M, Yan, Chunhong, Sizemore, Steven T, Narla, Goutham, Zhang, Junran

“…There is currently a lack of precise predictive biomarkers for patient selection in clinical trials of inhibitors targeting replication stress (RS) response…”
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Influencing factors of sleep disorders and sleep quality in healthcare workers during the COVID‐19 pandemic: A systematic review and meta‐analysis by Lv, Qian, Zhou, Wenguang, Kong, Yue, Chen, Silu, Xu, Baoling, Zhu, Fangfang, Shen, Xianying, Qiu, Zhaojun

“…Aim The aim of this study was to identify the influencing factors of sleep disorders and sleep quality in healthcare workers during the COVID‐19 pandemic…”
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ATR/CHK1 inhibitors and cancer therapy by Qiu, Zhaojun, Oleinick, Nancy L., Zhang, Junran

“…The cell cycle checkpoint proteins ataxia-telangiectasia-mutated-and-Rad3-related kinase (ATR) and its major downstream effector checkpoint kinase 1 (CHK1)…”
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Cloning and Characterization of a Calcium-Activated Chloride Channel in Rat Uterus by Song, Junfang, Zhang, Xiaojuan, Qi, Zhi, Sun, Gang, Chi, Shaopeng, Zhu, Zhaohui, Ren, Jiangong, Qiu, Zhaojun, Liu, Ka, Myatt, Leslie, Ma, Runlin Z

“…In a search for genes involved in regulation of uterine contractility, we cloned a novel calcium-activated chloride channel gene, named rat Clca4, from…”
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Cloning and Characterization of a Calcium-Activated Chloride Channel in Rat Uterus1 by Song, Junfang, Zhang, Xiaojuan, Qi, Zhi, Sun, Gang, Chi, Shaopeng, Zhu, Zhaohui, Ren, Jiangong, Qiu, Zhaojun, Liu, Ka, Myatt, Leslie, Ma, Runlin Z

“…In a search for genes involved in regulation of uterine contractility, we cloned a novel calcium-activated chloride channel gene, named rat Clca4, from…”
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A Novel Role for RNF126 in the Promotion of G2 Arrest via Interaction With 14-3-3σ by Fa, Pengyan, Qiu, Zhaojun, Wang, Qi-En, Yan, Chunhong, Zhang, Junran

“…Cell cycle checkpoints and DNA repair are important for cell survival after exogenous DNA damage. Both rapid blockage of G2 to M phase transition in the cell…”
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Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy by Hong, Zhipeng, Liu, Tao, Wan, Lingfeng, Fa, Pengyan, Kumar, Pankaj, Cao, Yanan, Prasad, Chandra Bhushan, Qiu, Zhaojun, Liu, Joseph, Wang, Hongbing, Li, Zaibo, Wang, Qi-En, Guo, Peixuan, Guo, Deliang, Yilmaz, Ayse S, Lu, Lanchun, Papandreou, Ioanna, Jacob, Naduparambil K, Yan, Chunhong, Zhang, Xiaoli, She, Qing-Bai, Ma, Zhefu, Zhang, Junran

“…Over 50% of all patients with cancer are treated with radiotherapy. However, radiotherapy is often insufficient as a monotherapy and requires a nontoxic…”
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The effect of abdominal massage on enteral nutrition tolerance in patients on mechanical ventilation: A Randomized Controlled Study by Zhang, Weiqin, Zhou, Wenguang, Kong, Yue, Li, Qi, Huang, Xiaoqiong, Zhao, Binbin, Su, Honghong, Chen, Silu, Shen, Xianying, Qiu, Zhaojun

“…To assess whether abdominal massage impacts enteral feeding tolerance in mechanically ventilated patients. Patients were randomized to receive standard or…”
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PP2A B55α inhibits epithelial-mesenchymal transition via regulation of Slug expression in non-small cell lung cancer by Singh, Deepika, Qiu, Zhaojun, Jonathan, Spehar M., Fa, Pengyan, Thomas, Hannah, Prasad, Chandra Bhushan, Cai, Shurui, Wang, Jing J., Yan, Chunhong, Zhang, Xiaoli, Venere, Monica, Li, Zaibo, Sizemore, Steven T., Wang, Qi-En, Zhang, Junran

“…PP2A B55α, encoded by PPP2R2A, acts as a regulatory subunit of the serine/threonine phosphatase PP2A. Despite a frequent loss of heterozygosity of PPP2R2A in…”
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Abstract B024: The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity by Prasad, Chandra Bhushan, Oo, Adrian, Qiu, Zhaojun, Li, Na, Singh, Deepika, Xin, Xiwen, Cho, Young-Jae, Li, Zaibo, Zhang, Xiaoli, Yan, Chunhong, Zheng, Qingfei, Shao, Jimin, Wang, Qi-En, Kim, Baek, Zhang, Junran

“…Abstract The replication stress (RS) response protein ataxia telangiectasia and Rad3-related protein (ATR) and its main downstream factor, checkpoint kinase 1…”
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RNF126 as a biomarker of a poor prognosis in invasive breast cancer and CHK1 inhibitor efficacy in breast cancer cells by Yang, Xiaosong, Pan, You, Qiu, Zhaojun, Du, Zhanwen, Zhang, Yao, Fa, Pengyan, Gorityala, Shashank, Ma, Shanhuai, Li, Shunqiang, Chen, Ceshi, Wang, Hongbing, Xu, Yan, Yan, Chunhong, Ruth, Keri, Ma, Zhefu, Zhang, Junran

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