Search Results - "Qiu, Wei‐Lin"

A single‐cell transcriptomic analysis reveals precise pathways and regulatory mechanisms underlying hepatoblast differentiation by Yang, Li, Wang, Wei‐Hua, Qiu, Wei‐Lin, Guo, Zhen, Bi, Erfei, Xu, Cheng‐Ran

“…How bipotential hepatoblasts differentiate into hepatocytes and cholangiocytes remains unclear. Here, using single‐cell transcriptomic analysis of…”
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Defining multistep cell fate decision pathways during pancreatic development at single‐cell resolution by Yu, Xin‐Xin, Qiu, Wei‐Lin, Yang, Liu, Zhang, Yu, He, Mao‐Yang, Li, Lin‐Chen, Xu, Cheng‐Ran

“…The generation of terminally differentiated cell lineages during organogenesis requires multiple, coordinated cell fate choice steps. However, this process has…”
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Sequential progenitor states mark the generation of pancreatic endocrine lineages in mice and humans by Yu, Xin-Xin, Qiu, Wei-Lin, Yang, Liu, Wang, Yan-Chun, He, Mao-Yang, Wang, Dan, Zhang, Yu, Li, Lin-Chen, Zhang, Jing, Wang, Yi, Xu, Cheng-Ran

“…The pancreatic islet contains multiple hormone + endocrine lineages (α, β, δ, PP and ε cells), but the developmental processes that underlie endocrinogenesis…”
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Dynamics of chromatin marks and the role of JMJD3 during pancreatic endocrine cell fate commitment by Yu, Xin-Xin, Qiu, Wei-Lin, Yang, Liu, Li, Lin-Chen, Zhang, Yu-Wei, Xu, Cheng-Ran

“…Pancreatic endocrine lineages are derived from pancreatic progenitors that undergo a cell fate transition requiring a switch from low to high Ngn3 expression…”
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Single‐cell transcriptomic analyses reveal distinct dorsal/ventral pancreatic programs by Li, Lin‐Chen, Qiu, Wei‐Lin, Zhang, Yu‐Wei, Xu, Zi‐Ran, Xiao, Yi‐Ni, Hou, Caiying, Yu, Peng, Cheng, Xin, Xu, Cheng‐Ran

“…The pancreas of vertebrates is separately derived from both the dorsal and ventral endodermal domains. However, the difference between these two programs has…”
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Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells by Feng, Sisi, Wu, Jiaying, Qiu, Wei-Lin, Yang, Li, Deng, Xiaogang, Zhou, Ying, Chen, Yabin, Li, Xiao, Yu, Lei, Li, Hongsheng, Xu, Zi-Ran, Xiao, Yini, Ren, Xiongzhao, Zhang, Ludi, Wang, Chenhua, Sun, Zhen, Wang, Jinglin, Ding, Xiaoyan, Chen, Yuelei, Gadue, Paul, Pan, Guoyu, Ogawa, Mina, Ogawa, Shinichiro, Na, Jie, Zhang, Peilin, Hui, Lijian, Yin, Hao, Chen, Luonan, Xu, Cheng-Ran, Cheng, Xin

“…The ever-increasing therapeutic and pharmaceutical demand for liver cells calls for systems that enable mass production of hepatic cells. Here we describe a…”
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Characterizing pancreatic β-cell heterogeneity in the streptozotocin model by single-cell transcriptomic analysis by Feng, Ye, Qiu, Wei-Lin, Yu, Xin-Xin, Zhang, Yu, He, Mao-Yang, Li, Lin-Chen, Yang, Li, Zhang, Weiyi, Franti, Michael, Ye, Junqing, Hoeck, Joerg D., Xu, Cheng-Ran

“…The streptozotocin (STZ) model is widely used in diabetes research. However, the cellular and molecular states of pancreatic endocrine cells in this model…”
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Deciphering Pancreatic Islet β Cell and α Cell Maturation Pathways and Characteristic Features at the Single-Cell Level by Qiu, Wei-Lin, Zhang, Yu-Wei, Feng, Ye, Li, Lin-Chen, Yang, Liu, Xu, Cheng-Ran

“…Pancreatic β and α cells play essential roles in maintaining glucose homeostasis. However, the mechanisms by which these distinct cell populations are…”
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Structure optimization of high indium content InGaAs/InP heterostructure for the growth of In0.82Ga0.18As buffer layer by Wei, Qiu-lin, Guo, Zuo-xing, Zhao, Lei, Zhao, Liang, Yuan, De-zeng, Miao, Guo-qing, Xia, Mao-sheng

“…Microstructure and misfit dislocation behavior in In x Ga 1- x As/InP heteroepitaxial materials grown by low pressure metal organic chemical vapor deposition…”
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TEM study of dislocations structure in In0.82Ga0.18As/InP heterostructure with InGaAs as buffer layer by Zhao, Liang, Guo, Zuo-xing, Yuan, De-zeng, Wei, Qiu-lin, Zhao, Lei

“…In order to improve the quality of detector, In x Ga 1− x As ( x =0.82) buffer layer has been introduced in In 0.82 Ga 0.18 As/InP heterostructure. Dislocation…”
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Single-cell patterning and axis characterization in the murine and human definitive endoderm by Li, Lin-Chen, Wang, Xin, Xu, Zi-Ran, Wang, Yan-Chun, Feng, Ye, Yang, Liu, Qiu, Wei-Lin, Yang, Li, Yu, Xin-Xin, Gu, Jun, Xu, Cheng-Ran

“…Defining the precise regionalization of specified definitive endoderm progenitors is critical for understanding the mechanisms underlying the generation and…”
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Single-cell Transcriptomic Analyses of Mouse Pancreatic Endocrine Cells by Li, Lin-Chen, Yu, Xin-Xin, Zhang, Yu-Wei, Feng, Ye, Qiu, Wei-Lin, Xu, Cheng-Ran

“…Pancreatic endocrine cells, which are clustered in islets, regulate blood glucose stability and energy metabolism. The distinct cell types in islets, including…”
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Deciphering Pancreatic Islet β Cell and α Cell Maturation Pathways and Characteristic Features at the Single-Cell Level by Qiu, Wei-Lin, Zhang, Yu-Wei, Feng, Ye, Li, Lin-Chen, Yang, Liu, Xu, Cheng-Ran

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Single-cell Transcriptomic Analyses of Mouse Pancreatic Endocrine Cells by Li, Lin-Chen, Yu, Xin-Xin, Zhang, Yu-Wei, Feng, Ye, Qiu, Wei-Lin, Xu, Cheng-Ran

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Genetic instability of BRCA1 gene at locus D17S855 is related to clinicopathological behaviors of gastric cancer from Chinese population by Chen, Xue-Rong, Zhang, Wei-Zhong, Lin, Xing-Qiu, Wang, Jin-Wei

“…AIM： To investigate genetic instability of gene BRCA1 at locus D17S855, and their relationship with clinicopathological characteristics of gastric cancer in…”
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Dynamic mechanical behavior of ultra-high strength steel 30CrMnSiNi2A at high strain rates and elevated temperatures by Niu, Qiu-lin, Ming, Wei-wei, Chen, Ming, Tang, Si-wen, Li, Peng-nan

“…During high speed machining in the field of manufacture,chip formation is a severe plastic deformation process including large strain,high strain rate and high…”
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Dynamic mechanical behavior of ultra-high strength steel 30CrMnSiNi2A at high strain rates and elevated temperatures by Qiu-lin Niu Wei-wei Ming Ming Chen Si-wen Tang Peng-nan Li

“…During high speed machining in the field of manufacture,chip formation is a severe plastic deformation process including large strain,high strain rate and high…”
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Modulation of Na_v1.8 by Lysophosphatidic Acid in the Induction of Bone Cancer Pain by Hai-Li Pan Ben-Long Liu Wei Lin Yu-Qiu Zhang

“…Given that lysophosphatidic acid（LPA） and the tetrodotoxin-resistant sodium channel Nav1.8 are both involved in bone cancer pain, the present study was…”
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Stochastic averaging of quasi partially integrable Hamiltonian systems under fractional Gaussian noise by Lü, Qiang-feng, Deng, Mao-lin, Zhu, Wei-qiu

“…A stochastic averaging method for predicting the response of quasi partially integrable and non-resonant Hamiltoniansystems to fractional Gaussian noise （fGla）…”
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Regional brain structural abnormality in ischemic stroke patients： a voxel-based morphometry study by Wu, Ping, Zhou, Yu-mei, Zeng, Fang, Li, Zheng-jie, Luo, Lu, Li, Yong-xin, Fan, Wei, Qiu, Li-hua, Qin, Wei, Chen, Lin, Bai, Lin, Nie, Juan, Zhang, San, Xiong, Yan, Bai, Yu, Yin, Can-xin, Liang, Fan-rong

“…Our previous study used regional homogeneity analysis and found that activity in some brain areas of patients with ischemic stroke changed significantly. In…”
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