Search Results - "Qiu, Liru"
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FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity
Published in Journal of the American Society of Nephrology (01-01-2018)“…Bile acids are ligands for the nuclear hormone receptor farnesoid X receptor (FXR) and the G protein-coupled receptor TGR5. We have shown that FXR and TGR5…”
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2
G Protein-Coupled Bile Acid Receptor TGR5 Activation Inhibits Kidney Disease in Obesity and Diabetes
Published in Journal of the American Society of Nephrology (01-05-2016)“…Obesity and diabetes mellitus are the leading causes of renal disease. In this study, we determined the regulation and role of the G protein-coupled bile acid…”
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3
Endocytosis of albumin by podocytes elicits an inflammatory response and induces apoptotic cell death
Published in PloS one (28-01-2013)“…The presence of albuminuria is strongly associated with progression of chronic kidney disease. While albuminuria has been shown to injure renal proximal…”
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4
CCL2 regulation of MST1-mTOR-STAT1 signaling axis controls BCR signaling and B-cell differentiation
Published in Cell death and differentiation (01-09-2021)“…Chemokines are important regulators of the immune system, inducing specific cellular responses by binding to receptors on immune cells. In SLE patients,…”
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5
CUBN gene mutations may cause focal segmental glomerulosclerosis (FSGS) in children
Published in BMC nephrology (03-01-2022)“…Imerslund-Gräsbeck Syndrome (IGS) is mainly caused by CUBN gene biallelic mutations. Proteinuria accompanies IGS specific symptoms in about half of the…”
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Mutations in the NUP93, NUP107 and NUP160 genes cause steroid-resistant nephrotic syndrome in Chinese children
Published in Italian journal of pediatrics (22-04-2024)“…The variants of nucleoporins are extremely rare in hereditary steroid-resistant nephrotic syndrome (SRNS). Most of the patients carrying such variants progress…”
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Steroid-resistant nephrotic syndrome associated with certain SGPL1 variants in a family: Case report and literature review
Published in Frontiers in pediatrics (16-02-2023)“…Steroid-resistant nephrotic syndrome (SRNS) is a clinical syndrome characterized by the lack of response to standard steroid therapy, usually progressing to…”
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Long-Term Clinical and Immunological Impact of Severe COVID-19 on a Living Kidney Transplant Recipient – A Case Report
Published in Frontiers in immunology (08-09-2021)“…The long-term impact of COVID-19 on transplant recipients remains unknown. We describe the case of a 30-year-old male kidney transplant recipient from Wuhan,…”
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Liver X receptors preserve renal glomerular integrity under normoglycaemia and in diabetes in mice
Published in Diabetologia (01-02-2014)“…Aims/hypothesis Liver X receptors (LXRs) α and β are nuclear hormone receptors that are widely expressed in the kidney. They promote cholesterol efflux from…”
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Clinical and Renal Histology Findings and Different Responses to Induction Treatment Affecting the Long-Term Renal Outcomes of Children With ANCA-Associated Vasculitis: a Single-Center Cohort Analysis
Published in Frontiers in immunology (14-04-2022)“…Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is relatively rare in children. This article aimed to analyze clinical and renal…”
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Global Existence and Uniform Energy Decay Rates for the Semilinear Parabolic Equation with a Memory Term and Mixed Boundary Condition
Published in Abstract and Applied Analysis (01-01-2013)“…This work is concerned with a mixed boundary value problem for the semilinear parabolic equation with a memory term and generalized Lewis functions which…”
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Recommendations for the Diagnosis, Prevention, and Control of Coronavirus Disease-19 in Children—The Chinese Perspectives
Published in Frontiers in pediatrics (05-11-2020)“…Ever since SARS-CoV-2 began infecting people by the end of 2019, of whom some developed severe pneumonia (about 5%), which could be fatal (case fatality…”
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13
SGLT2 Protein Expression Is Increased in Human Diabetic Nephropathy
Published in The Journal of biological chemistry (01-03-2017)“…There is very limited human renal sodium gradient-dependent glucose transporter protein (SGLT2) mRNA and protein expression data reported in the literature…”
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14
Are They Just Two Children COVID-19 Cases Confused With Flu?
Published in Frontiers in pediatrics (05-06-2020)“…COVID-19, an emerging infectious disease, has quickly spread all over the world. All human populations are susceptible to this disease. Here we present two…”
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Simultaneous mutations of LAMB2 and NPHP1genes in a Chinese girl with isolated congenital nephrotic syndrome: a case report
Published in BMC pediatrics (22-03-2016)“…LAMB2 mutations cause Pierson syndrome (OMIM 609049), an autosomal recessive genetic disease typically characterized by congenital nephrotic syndrome (CNS) and…”
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SGLT2 Protein Expression Is Increased in Human Diabetic Nephropathy: SGLT2 PROTEIN INHIBITION DECREASES RENAL LIPID ACCUMULATION, INFLAMMATION, AND THE DEVELOPMENT OF NEPHROPATHY IN DIABETIC MICE
Published in The Journal of biological chemistry (31-03-2017)“…There is very limited human renal sodium gradient-dependent glucose transporter protein (SGLT2) mRNA and protein expression data reported in the literature…”
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17
Zero‐contrast PTRA and stenting for child with TRAS: A case report
Published in Pediatric transplantation (01-03-2022)“…Background Kidney transplantation is often complicated by TRAS, and PTRA can effectively treat it. However, PTRA is not appropriate for patients with CKD…”
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18
Early onset stage III diabetic nephropathy in a child with Prader-Willi syndrome treated with dulaglutide: a case report
Published in Translational pediatrics (31-05-2024)“…Prader-Willi syndrome (PWS) is a multisystem genetic disorder caused by chromosomal imprinting gene defects, with approximately 70% of cases resulting from…”
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SUCCESSFUL PREEMPTIVE KIDNEY TRANSPLANTATION WITH SIMULTANEOUS BILATERAL NEPHRECTOMY IN YOUNG INFANTS WITH CONGENITAL NEPHROTIC SYNDROME
Published in Transplantation (01-09-2020)Get full text
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Clinical, histological and molecular characteristics of Alport syndrome in Chinese children
Published in Journal of nephrology (01-06-2023)“…Background Alport syndrome is caused by COL4A3, COL4A4, or COL4A5 gene mutations. The present study aims to compare the clinicopathological features, gene…”
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