Search Results - "Qingfeng He"
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Sulforaphane ameliorates cadmium induced hepatotoxicity through the up-regulation of /Nrf2/ARE pathway and the inactivation of NF-κB
Published in Journal of functional foods (01-02-2021)“…[Display omitted] •SFN effectivelly scavenges free radicals and ROS induced by cadmium.•Antioxidation and anti-inflammation contribute to the hepatoprotection…”
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2
Foretinib Is Effective against Triple-Negative Breast Cancer Cells MDA-MB-231 In Vitro and In Vivo by Down-Regulating p-MET/HGF Signaling
Published in International journal of molecular sciences (01-01-2023)“…This study investigated the antitumor effects of foretinib on triple-negative breast cancer cells MDA-MB-231 xenograft tumors in vivo underlying phosphorylated…”
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Study on a new air-gap membrane distillation module for desalination
Published in Desalination (03-02-2014)“…A new air-gap membrane distillation (AGMD) module for desalination with internal latent-heat-recovery which consisted of parallel hollow fiber membranes and…”
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4
Research and development of Chinese anti-COVID-19 drugs
Published in Acta pharmaceutica Sinica. B (01-12-2022)“…The outbreak and spread of coronavirus disease 2019 (COVID-19) highlighted the importance and urgency of the research and development of therapeutic drugs…”
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5
Novel Entropy and Rotation Forest-Based Credal Decision Tree Classifier for Landslide Susceptibility Modeling
Published in Entropy (Basel, Switzerland) (23-01-2019)“…Landslides are a major geological hazard worldwide. Landslide susceptibility assessments are useful to mitigate human casualties, loss of property, and damage…”
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Modeling and optimization of air gap membrane distillation system for desalination
Published in Desalination (01-12-2014)“…In this paper, the experiments of desalinating the NaCl aqueous solution were carried out using an air gap membrane distillation module with energy recovery…”
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Utilization of Physiologically Based Pharmacokinetic Modeling in Pharmacokinetic Study of Natural Medicine: An Overview
Published in Molecules (Basel, Switzerland) (01-12-2022)“…Natural medicine has been widely used for clinical treatment and health care in many countries and regions. Additionally, extracting active ingredients from…”
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Real-world safety of PCSK9 inhibitors: A pharmacovigilance study based on spontaneous reports in FAERS
Published in Frontiers in pharmacology (24-11-2022)“…We aimed to evaluate alirocumab- and evolocumab-related adverse events (AEs) in real-world compared with all other drugs, overall and by gender and age…”
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Examination of the Impact of CYP3A4/5 on Drug-Drug Interaction between Schizandrol A/Schizandrol B and Tacrolimus (FK-506): A Physiologically Based Pharmacokinetic Modeling Approach
Published in International journal of molecular sciences (19-04-2022)“…Schizandrol A (SZA) and schizandrol B (SZB) are two active ingredients of Wuzhi capsule (WZC), a Chinese proprietary medicine commonly prescribed to alleviate…”
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10
Validation of the Simplified Chinese Version of the Brief Diabetes Quality of Life (DQoL) Questionnaire Based on a Cross-Sectional Study
Published in International journal of environmental research and public health (26-11-2020)“…(1) Objective: To assess the reliability and validity of the simplified Chinese version of the brief Diabetes Quality of Life (DQoL) questionnaire in measuring…”
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Pharmacokinetics of Novel Furoxan/Coumarin Hybrids in Rats Using LC-MS/MS Method and Physiologically Based Pharmacokinetic Model
Published in Molecules (Basel, Switzerland) (13-01-2023)“…Novel furoxan/coumarin hybrids were synthesized, and pharmacologic studies showed that the compounds displayed potent antiproliferation activities via…”
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Establishment and Evaluation of a Parametric Population Pharmacokinetic Model Repository for Ganciclovir and Valganciclovir
Published in Pharmaceutics (23-06-2023)“…Ganciclovir and valganciclovir are used for prophylaxis and treatment of cytomegalovirus infection. However, there is great interindividual variability in…”
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13
Experimental study of hollow fiber AGMD modules with energy recovery for high saline water desalination
Published in Desalination (01-07-2014)“…Hollow fiber AGMD modules with energy recovery for high saline water desalination were successfully developed by using parallel hollow fiber membranes and…”
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14
Simultaneous Quantitation of S(+)- and R(-)-Baclofen and Its Metabolite in Human Plasma and Cerebrospinal Fluid using LC-APCI-MS/MS: An Application for Clinical Studies
Published in Molecules (Basel, Switzerland) (08-01-2020)“…Baclofen is a racemic mixture that is commonly used for the treatment for spasticity. However, the optimal dose and dosing interval to achieve effective…”
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Application of Physiologically Based Pharmacokinetic Modeling in Preclinical Studies: A Feasible Strategy to Practice the Principles of 3Rs
Published in Frontiers in pharmacology (12-05-2022)“…Pharmacokinetic characterization plays a vital role in drug discovery and development. Although involving numerous laboratory animals with error-prone,…”
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Investigation of the Impact of CYP3A5 Polymorphism on Drug-Drug Interaction between Tacrolimus and Schisantherin A/Schisandrin A Based on Physiologically-Based Pharmacokinetic Modeling
Published in Pharmaceuticals (Basel, Switzerland) (27-02-2021)“…Wuzhi capsule (WZC) is commonly prescribed with tacrolimus in China to ease drug-induced hepatotoxicity. Two abundant active ingredients, schisantherin A (STA)…”
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17
Numerical Simulation on Impact Test of CFRP Strengthened Reinforced Concrete Beams
Published in Frontiers in materials (04-08-2020)“…As the main horizontal load-bearing member, the research on the impact resistance of reinforced concrete beams is an important part of the design of building…”
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Population pharmacokinetics of Amisulpride in Chinese patients with schizophrenia with external validation: the impact of renal function
Published in Frontiers in pharmacology (04-09-2023)“…Introduction: Amisulpride is primarily eliminated via the kidneys. Given the clear influence of renal clearance on plasma concentration, we aimed to explicitly…”
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Study on the Effect of Bond Strength on the Failure Mode of Coarse-Grained Sandstone in Weakly Cemented Stratum
Published in Minerals (Basel) (01-01-2022)“…Bond strength is one of the most important parameters and can affect the macroscopic mechanical properties and the damage state of rock to some degree…”
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Simultaneous Quantification of Propylthiouracil and Its N -β-d Glucuronide by HPLC-MS/MS: Application to a Metabolic Study
Published in Pharmaceuticals (Basel, Switzerland) (20-11-2021)“…Propylthiouracil (PTU) is commonly prescribed for the management of hyperthyroidism and thyrotoxicosis. Although the exact mechanism of action is not fully…”
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