Search Results - "Qing, Guangchao"
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Thermo-responsive triple-function nanotransporter for efficient chemo-photothermal therapy of multidrug-resistant bacterial infection
Published in Nature communications (24-09-2019)“…New strategies with high antimicrobial efficacy against multidrug-resistant bacteria are urgently desired. Herein, we describe a smart triple-functional…”
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Proton-driven transformable nanovaccine for cancer immunotherapy
Published in Nature nanotechnology (01-12-2020)“…Cancer vaccines hold great promise for improved cancer treatment. However, endosomal trapping and low immunogenicity of tumour antigens usually limit the…”
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An amphiphilic dendrimer as a light-activable immunological adjuvant for in situ cancer vaccination
Published in Nature communications (16-08-2021)“…Immunological adjuvants are essential for successful cancer vaccination. However, traditional adjuvants have some limitations, such as lack of controllability…”
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High‐Fidelity Determination and Tracing of Small Extracellular Vesicle Cargoes
Published in Small (Weinheim an der Bergstrasse, Germany) (01-10-2020)“…Direct tracing of small extracellular vesicle (sEV) cargoes holds unprecedented importance for elucidating the mechanisms involved in intercellular…”
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A natural killer T cell nanoagonist-initiated immune cascade for hepatocellular carcinoma synergistic immunotherapy
Published in Nanoscale (13-06-2024)“…Natural killer T (NKT) cell-mediated immunotherapy shows great promise in hepatocellular carcinoma featuring an inherent immunosuppressive microenvironment…”
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Effect of physicochemical properties on in vivo fate of nanoparticle-based cancer immunotherapies
Published in Acta pharmaceutica Sinica. B (01-04-2021)“…Current advances of immunotherapy have greatly changed the way of cancer treatment. At the same time, a great number of nanoparticle-based cancer…”
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Functionalized Macrophage Exosomes with Panobinostat and PPM1D‐siRNA for Diffuse Intrinsic Pontine Gliomas Therapy
Published in Advanced science (01-07-2022)“…Diffuse intrinsic pontine glioma (DIPG) is a rare and fatal pediatric brain tumor. Mutation of p53‐induced protein phosphatase 1 (PPM1D) in DIPG cells promotes…”
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DNA Damage Inducer Mitoxantrone Amplifies Synergistic Mild‐Photothermal Chemotherapy for TNBC via Decreasing Heat Shock Protein 70 Expression
Published in Advanced science (01-06-2023)“…Patients with triple‐negative breast cancer (TNBC) have the worst clinical outcomes when compared to other subtypes of breast cancer. Nanotechnology‐assisted…”
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Conformation Dependent Architectures of Assembled Antimicrobial Peptides with Enhanced Antimicrobial Ability
Published in Advanced healthcare materials (01-11-2023)“…Antimicrobial peptides (AMPs) are a developing class of natural and synthetic oligopeptides with host defense mechanisms against a broad spectrum of…”
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Traditional Chinese Medicine Formulae QY305 Reducing Cutaneous Adverse Reaction and Diarrhea by its Nanostructure
Published in Advanced science (01-02-2024)“…Traditional Chinese medicine (TCM) is widely used in clinical practice, including skin and gastrointestinal diseases. Here, a potential TCM QY305 (T‐QY305) is…”
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Natural and engineered bacterial outer membrane vesicles
Published in Biophysics reports (01-08-2019)“…Bacterial outer membrane vesicle (OMV) is a kind of spherical lipid bilayer nanostructure naturally secreted by bacteria, which has diverse functions such as…”
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Rolling Circular Amplification (RCA)-Assisted CRISPR/Cas9 Cleavage (RACE) for Highly Specific Detection of Multiple Extracellular Vesicle MicroRNAs
Published in Analytical chemistry (Washington) (21-01-2020)“…Multiplexed detection of extracellular vesicle (EV)-derived microRNAs (miRNAs) plays a critical role in facilitating disease diagnosis and prognosis…”
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Sulfur-Doped NiFe Hydroxide Nanobowls with Wrinkling Patterns for Photothermal Cancer Therapy
Published in ACS nano (24-10-2023)“…Hierarchical multiscale wrinkling nanostructures have shown great promise for many biomedical applications, such as cancer diagnosis and therapy. However,…”
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Nanomaterials with changeable physicochemical property for boosting cancer immunotherapy
Published in Journal of controlled release (01-02-2022)“…The past decade has witnessed a great progress in cancer immunotherapy with the sequential approvals of therapeutic cancer vaccine, immune checkpoint inhibitor…”
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De novo design of highly efficient type-I photosensitizer based on π-conjugated oligomer for photodynamic eradication of multidrug-resistant bacterial infections
Published in Chinese chemical letters (01-03-2024)“…Traditional photosensitizers show limited singlet oxygen generation in hypoxic infection lesions, which greatly suppress their performance in antibacterial…”
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Bioorthogonal Chemistry-Guided Inhalable Nanoprodrug to Circumvent Cisplatin Resistance in Orthotopic Nonsmall Cell Lung Cancer
Published in ACS nano (09-11-2024)“…Pulmonary delivery of anticancer therapeutics has shown encouraging performance in treating nonsmall cell lung cancer (NSCLC), which is characterized by high…”
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Engineered Exosomes with Ouabain for H3K27M‐Mutated DIPG Therapy
Published in Advanced functional materials (15-10-2024)“…Abstract Diffuse intrinsic pontine glioma (DIPG) is a highly lethal tumor that occurs in the brain stem. At present, there is no effective drug for DIPG. In…”
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Structure transformable nanoparticles for photoacoustic imaging-guided photothermal ablation of tumors via enzyme-induced multistage delivery
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (01-10-2021)“…•Transformable CuS@GNPs realized enzyme-induced multistage delivery to tumor.•The multistage delivery behavior of CuS@GNPs enhances the photothermal…”
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Flipped Quick-Response Code Enables Reliable Blood Grouping
Published in ACS nano (27-04-2021)“…Accurate and rapid blood typing plays a vital role in a variety of biomedical and forensic scenarios, but recognizing weak agglutination remains challenging…”
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Small Extracellular Vesicles: High‐Fidelity Determination and Tracing of Small Extracellular Vesicle Cargoes (Small 40/2020)
Published in Small (Weinheim an der Bergstrasse, Germany) (08-10-2020)“…In article number 2002800, Guixue Wang, Yang Luo, and co‐workers introduce a DNA origami nanoprobe “fLIGHT” for high‐fidelity visualization of small…”
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