Search Results - "Qin, Shurong"
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The Gut-Microglia Connection: Implications for Central Nervous System Diseases
Published in Frontiers in immunology (05-10-2018)“…The importance of the gut microbiome in central nervous system (CNS) diseases has long been recognized; however, research into this connection is limited, in…”
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Herpes Simplex Virus 1 Induces Microglia Gasdermin D-Dependent Pyroptosis Through Activating the NLR Family Pyrin Domain Containing 3 Inflammasome
Published in Frontiers in microbiology (21-03-2022)“…Herpes simplex virus type 1 (HSV-1) is a highly prevalent virus in humans and causes severe forms of inflammation, such as herpes simplex encephalitis (HSE)…”
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Intestinal Microbiota-Associated Metabolites: Crucial Factors in the Effectiveness of Herbal Medicines and Diet Therapies
Published in Frontiers in physiology (29-10-2019)“…Although the efficacy of herbal medicines (HMs) and traditional Chinese medicines (TCMs) in human diseases has long been recognized, their development has been…”
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Hsp90 Inhibitors Prevent HSV-1 Replication by Directly Targeting UL42-Hsp90 Complex
Published in Frontiers in microbiology (03-02-2022)“…Herpes simplex virus type I (HSV-1) is a member of the Alphaherpesvirinae family, which could initiate labial herpes caused by the reactivation of HSV-1…”
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Artemvulactone E isolated from Artemisia vulgaris L. ameliorates lipopolysaccharide-induced inflammation in both RAW264.7 and zebrafish model
Published in Frontiers in pharmacology (18-07-2024)“…Natural plants are valuable resources for exploring new bioactive compounds. L. is a traditional Chinese medicinal herb that has been historically used for…”
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Hsp90 Inhibitors Inhibit the Entry of Herpes Simplex Virus 1 Into Neuron Cells by Regulating Cofilin-Mediated F-Actin Reorganization
Published in Frontiers in microbiology (10-01-2022)“…Herpes simplex virus 1 (HSV-1) is a common neurotropic virus, the herpes simplex encephalitis (HSE) caused by which is considered to be the most common…”
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Anti-HSV-1 activity of Aspergillipeptide D, a cyclic pentapepetide isolated from fungus Aspergillus sp. SCSIO 41501
Published in Virology journal (19-03-2020)“…Herpes simplex virus 1, an enveloped DNA virus belonging to the Herpesviridae family, spreads to neurons and causes pathological changes in the central nervous…”
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Oleanolic Acid Derivative AXX-18 Exerts Antiviral Activity by Inhibiting the Expression of HSV-1 Viral Genes UL8 and UL52
Published in Viruses (13-06-2022)“…Two-thirds of the world’s population is infected with HSV-1, which is closely associated with many diseases, such as Gingival stomatitis and viral…”
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Logic-gated tumor-microenvironment nanoamplifier enables targeted delivery of CRISPR/Cas9 for multimodal cancer therapy
Published in Acta pharmaceutica Sinica. B (01-02-2024)“…Recent innovations in nanomaterials inspire abundant novel tumor-targeting CRISPR-based gene therapies. However, the therapeutic efficiency of traditional…”
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Correction to: Anti-HSV-1 activity of Aspergillipeptide D, a cyclic pentapeptide isolated from fungus Aspergillus sp. SCSIO 41501
Published in Virology journal (01-04-2020)“…Following publication of the original article [1], we have been notified that there is a typo in the title of this article…”
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The Curcumin Analogs 2-Pyridyl Cyclohexanone Induce Apoptosis via Inhibition of the JAK2-STAT3 Pathway in Human Esophageal Squamous Cell Carcinoma Cells
Published in Frontiers in pharmacology (21-08-2018)“…Multiple modifications to the structure of curcumin have been investigated with an aim to improve its potency and biochemical properties. Previously, we have…”
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A comprehensive investigation of the mRNA and protein level of ACE2, the putative receptor of SARS-CoV-2, in human tissues and blood cells
Published in International journal of medical sciences (01-01-2020)“…The outbreak of pneumonia caused by SARS-CoV-2 posed a great threat to global human health, which urgently requires us to understand comprehensively the…”
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Bacteria proliferation-mediated cascade amplification for visually ultrasensitive detection of extracellular vesicles
Published in Sensors and actuators. B, Chemical (01-06-2024)“…In molecular diagnostics, there exist challenges in effectively isolating and sensitively detecting biomarkers such as extracellular vesicles…”
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Spatiotemporal Delivery of Dual Nanobodies by Engineered Probiotics to Reverse Tumor Immunosuppression via Targeting Tumor-Derived Exosomes
Published in ACS nano (01-10-2024)“…The anti-PD-L1 and its bispecific antibodies have exhibited durable antitumor immunity but still elicit immunosuppression mainly caused by tumor-derived…”
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Microfluidic Synthesis of CuH Nanoparticles for Antitumor Therapy through Hydrogen-Enhanced Apoptosis and Cuproptosis
Published in ACS nano (26-03-2024)“…Cuproptosis has drawn enormous attention in antitumor material fields; however, the responsive activation of cuproptosis against tumors using nanomaterials…”
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A bioorthogonal probiotic platform spatiotemporally releases nanobodies in deep tumor for cancer chemoimmunotherapy
Published in Materials today (Kidlington, England) (01-09-2024)Get full text
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Self-Metallized Whole Cell Vaccines Prepared by Microfluidics for Bioorthogonally Catalyzed Antitumor Immunotherapy
Published in ACS nano (19-03-2024)“…Tumor whole cell, carrying a complete set of tumor-associated antigens and tumor-specific antigens, has shown great potential in the construction of tumor…”
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Roles of HSV-1 infection-induced microglial immune responses in CNS diseases: friends or foes?
Published in Critical reviews in microbiology (02-11-2019)“…Microglia, as brain-resident macrophages, are the first line of defense against brain invading pathogens. Further, their dysfunction has been recognized to be…”
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Self‐Generating Gold Nanocatalysts in Autologous Tumor Cells for Targeted Catalytic Immunotherapy
Published in Advanced healthcare materials (01-06-2024)“…Employing tumor whole cells for tumor immunotherapy is a promising tumor therapy proposed in the early stage, but its therapeutic efficacy is weakened by the…”
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Single-cell RNA-sequencing analysis identifies host long noncoding RNA MAMDC2-AS1 as a co-factor for HSV-1 nuclear transport
Published in International journal of biological sciences (01-01-2020)“…Herpes simplex virus (HSV) type 1 (HSV-1) infection exhibited high heterogeneity at individual cells level, including the different gene expression patterns…”
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