Search Results - "Qin, Shu‐Kui"

Icaritin‐induced immunomodulatory efficacy in advanced hepatitis B virus‐related hepatocellular carcinoma: Immunodynamic biomarkers and overall survival by Qin, Shu‐Kui, Li, Qing, Ming Xu, Jian, Liang, Jun, Cheng, Ying, Fan, Ying, Jiang, Jun, Ye, Hao, Tao, Huimin, Li, Lian, Zheng, Limin, Wei, Zhaohui, Li, Shu, Meng, Kun, Ye, Bin, Sun, Yan

“…Advanced hepatitis B virus (HBV)‐related hepatocellular carcinoma HCC with poor prognosis is often associated with chronic inflammation, immune tolerance, and…”
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Randomized Phase III KEYNOTE-181 Study of Pembrolizumab Versus Chemotherapy in Advanced Esophageal Cancer by Kojima, Takashi, Shah, Manish A, Muro, Kei, Francois, Eric, Adenis, Antoine, Hsu, Chih-Hung, Doi, Toshihiko, Moriwaki, Toshikazu, Kim, Sung-Bae, Lee, Se-Hoon, Bennouna, Jaafar, Kato, Ken, Shen, Lin, Enzinger, Peter, Qin, Shu-Kui, Ferreira, Paula, Chen, Jia, Girotto, Gustavo, de la Fouchardiere, Christelle, Senellart, Helene, Al-Rajabi, Raed, Lordick, Florian, Wang, Ruixue, Suryawanshi, Shailaja, Bhagia, Pooja, Kang, S Peter, Metges, Jean-Philippe

“…Patients with advanced esophageal cancer have a poor prognosis and limited treatment options after first-line chemotherapy. In this open-label, phase III…”
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Pembrolizumab plus trastuzumab and chemotherapy for HER2-positive gastric or gastro-oesophageal junction adenocarcinoma: interim analyses from the phase 3 KEYNOTE-811 randomised placebo-controlled trial by Janjigian, Yelena Y, Kawazoe, Akihito, Bai, Yuxian, Xu, Jianming, Lonardi, Sara, Metges, Jean Phillipe, Yanez, Patricio, Wyrwicz, Lucjan S, Shen, Lin, Ostapenko, Yuriy, Bilici, Mehmet, Chung, Hyun Cheol, Shitara, Kohei, Qin, Shu-Kui, Van Cutsem, Eric, Tabernero, Josep, Li, Kan, Shih, Chie-Schin, Bhagia, Pooja, Rha, Sun Young

“…Evidence for the efficacy of combined PD-1 and HER2 blockade with chemotherapy on progression-free and overall survival in HER2-positive gastro-oesophageal…”
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Progress in systemic therapy of advanced hepatocellular carcinoma by Gong, Xin-Lei, Qin, Shu-Kui

“…Primary liver cancer, mainly consisting of hepatocellular carcinoma(HCC), is one of common malignancies worldwide, and prevalent among the Chinese population…”
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Lapatinib Plus Paclitaxel Versus Paclitaxel Alone in the Second-Line Treatment of HER2-Amplified Advanced Gastric Cancer in Asian Populations: TyTAN— A Randomized, Phase III Study by SATOH, Taroh, XU, Rui-Hua, MIWA, Hiroto, QIN, Shu-Kui, CHUNG, Ik-Joo, YEH, Kun-Huei, FENG, Ji-Feng, MUKAIYAMA, Akihira, KOBAYASHI, Mikiro, OHTSU, Atsushi, BANG, Yung-Jue, HYUN CHEOL CHUNG, SUN, Guo-Ping, DOI, Toshihiko, XU, Jian-Ming, TSUJI, Akihito, OMURO, Yasushi, JIN LI, WANG, Jin-Wan

“…In Asian countries, paclitaxel once per week is used as second-line treatment in advanced gastric cancer, including human epidermal growth factor receptor 2…”
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Pembrolizumab versus paclitaxel for previously treated advanced gastric or gastroesophageal junction cancer (KEYNOTE‐063): A randomized, open‐label, phase 3 trial in Asian patients by Chung, Hyun Cheol, Kang, Yoon‐Koo, Chen, Zhendong, Bai, Yuxian, Wan Ishak, Wan Zamaniah, Shim, Byoung Yong, Park, Young Lee, Koo, Dong‐Hoe, Lu, Jianwei, Xu, Jianming, Chon, Hong Jae, Bai, Li‐Yuan, Zeng, Shan, Yuan, Ying, Chen, Yen‐Yang, Gu, Kangsheng, Zhong, Wen Yan, Kuang, Shu, Shih, Chie‐Schin, Qin, Shu‐Kui

“…Background KEYNOTE‐063 (NCT03019588) investigated pembrolizumab versus paclitaxel as second‐line therapy in Asian patients with advanced programmed death…”
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Guidelines for Diagnosis and Treatment of Primary Liver Cancer in China (2017 Edition) by Zhou, Jian, Sun, Hui-Chuan, Wang, Zheng, Cong, Wen-Ming , Wang, Jian-Hua, Zeng, Meng-Su, Yang, Jia-Mei, Bie, Ping, Liu, Lian-Xin, Wen, Tian-Fu, Han, Guo-Hong, Wang, Mao-Qiang, Liu, Rui-Bao, Lu, Li-Gong, Ren, Zheng-Gang, Chen, Min-Shan, Zeng, Zhao-Chong, Liang, Ping, Liang, Chang-Hong, Chen, Min, Yan, Fu-Hua, Wang, Wen-Ping, Ji, Yuan, Cheng, Wen-Wu, Dai, Chao-Liu, Jia, Wei-Dong, Li, Ya-Ming, Li, Ye-Xiong, Liang, Jun, Liu, Tian-Shu, Lv, Guo-Yue, Mao, Yi-Lei, Ren, Wei-Xin, Shi, Hong-Cheng, Wang, Wen-Tao, Wang, Xiao-Ying, Xing, Bao-Cai, Xu, Jian-Ming, Yang, Jian-Yong, Yang, Ye-Fa, Ye, Sheng-Long, Yin, Zheng-Yu, Zhang, Bo-Heng, Zhang, Shui-Jun, Zhou, Wei-Ping, Zhu, Ji-Ye, Liu, Rong, Shi, Ying-Hong, Xiao, Yong-Sheng, Dai, Zhi, Teng, Gao-Jun, Cai, Jian-Qiang, Wang, Wei-Lin, Dong, Jia-Hong, Li, Qiang, Shen, Feng, Qin, Shu-Kui, Fan, Jia

“…Background: Hepatocellular carcinoma (HCC) (about 85–90% of primary liver cancer) is particularly prevalent in China because of the high prevalence of chronic…”
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HER2 Status in Advanced or Metastatic Gastric, Esophageal, or Gastroesophageal Adenocarcinoma for Entry to the TRIO-013/LOGiC Trial of Lapatinib by Press, Michael F, Ellis, Catherine E, Gagnon, Robert C, Grob, Tobias J, Buyse, Marc, Villalobos, Ivonne, Liang, Zhiyong, Wu, Shafei, Bang, Yung-Jue, Qin, Shu-Kui, Chung, Hyun Cheol, Xu, Jianming, Park, Joon Oh, Jeziorski, Krzysztof, Afenjar, Karen, Ma, Yanling, Estrada, Monica C, Robinson, Douglas M, Scherer, Stefan J, Sauter, Guido, Hecht, J Randolph, Slamon, Dennis J

“…HER2/ERBB2 status is used to select patients for HER2-targeted therapy. HER2/ERBB2 amplification/overexpression of upper gastrointestinal (UGI) adenocarcinomas…”
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A multicenter clinical study: personalized medication for advanced gastrointestinal carcinomas with the guidance of patient-derived tumor xenograft (PDTX) by Cheng, Yuan, Qin, Shu-kui, Li, Jin, Dai, Guang-hai, Shen, Bai-yong, Ying, Jie-er, Ba, Yi, Liang, Han, Wang, Xin-bo, Xu, Ye, Zhou, Lin, Ding, Ke-feng, Qin, Yan-ru, Yang, Shu-jun, Guan, Wen-xian, Zheng, Hui, Wang, Qian, Song, Hang, Zhu, Yan-ping

“…Background Establish patient-derived tumor xenograft (PDTX) from advanced GICs and assess the clinical value and applicability of PDTX for the treatment of…”
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Impaired gap junctions in human hepatocellular carcinoma limit intrinsic oxaliplatin chemosensitivity: A key role of connexin 26 by YANG, YAN, ZHU, JIAN, ZHANG, NA, ZHAO, YU, LI, WAN-YUN, ZHAO, FU-YOU, OU, YU-RONG, QIN, SHU-KUI, WU, QIONG

“…Hepatocellular carcinoma (HCC) is generally believed to have low sensitivity to chemotherapeutic agents including oxaliplatin (OXA). Studies have demonstrated…”
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Efficacy and safety of first-line sunitinib in Chinese patients with metastatic renal cell carcinoma by Qin, Shu-Kui, Jin, Jie, Guo, Jun, Wang, Jin-Wan, Zhou, Fang-Jian, Huang, Yi-Ran, Ren, Xiu-Bao, Ye, Ding-Wei, Pan, Sharon, Sajben, Peter, Wang, Qiao

“…We report the first prospective study of sunitinib for metastatic renal cell carcinoma (mRCC) in China. Chinese mRCC patients received first-line sunitinib 50…”
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Lobaplatin arrests cell cycle progression in human hepatocellular carcinoma cells by Wu, Qiong, Qin, Shu-Kui, Teng, Feng-Meng, Chen, Chang-Jie, Wang, Rui

“…Hepatocellular carcinoma (HCC) still is a big burden for China. In recent years, the third-generation platinum compounds have been proposed as potential active…”
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First-line pembrolizumab/placebo plus trastuzumab and chemotherapy in HER2-positive advanced gastric cancer: KEYNOTE-811 by Chung, Hyun Cheol, Bang, Yung-Jue, S Fuchs, Charles, Qin, Shu-Kui, Satoh, Taroh, Shitara, Kohei, Tabernero, Josep, Van Cutsem, Eric, Alsina, Maria, Cao, Zhu Alexander, Lu, Jia, Bhagia, Pooja, Shih, Chie-Schin, Janjigian, Yelena Y

“…Treatment options for patients with HER2-positive advanced gastric cancer are limited, and the prognosis for these patients is poor. Pembrolizumab has…”
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Efficacy and safety of the oxaliplatin-based chemotherapy in the treatment of advanced primary hepatocellular carcinoma: A meta-analysis of prospective studies by Liu, Lin, Zheng, Ying-hui, Han, Li, Qin, Shu-Kui

“…Many clinical studies have demonstrated the survival benefits of oxaliplatin-based chemotherapy for advanced hepatocellular carcinoma patients. Therefore, we…”
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A Phase Ib Study of Lucitanib (AL3810) in a Cohort of Patients with Recurrent and Metastatic Nasopharyngeal Carcinoma by Zhang, Yang, Luo, Fan, Ma, Yu-Xiang, Liu, Qian-Wen, Yang, Yun-Peng, Fang, Wen-Feng, Huang, Yan, Zhou, Ting, Li, Jin, Pan, Hong-Ming, Yang, Lei, Qin, Shu-Kui, Zhao, Hong-Yun, Zhang, Li

“…Lucitanib is a novel multi-target inhibitor of FGFR1-3, VEGFR 1-3, and PDGFR α/β. Here, we evaluated the safety, tolerability, and preliminary efficacy of…”
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XPC Lys939Gln polymorphism is associated with the decreased response to platinum based chemotherapy in advanced non-small-cell lung cancer by Zhu, Xiao-Li, Sun, Xin-Chen, Chen, Bao-An, Sun, Ning, Cheng, Hong-Yan, Li, Fan, Zhang, Hong-Ming, Feng, Ji-Feng, Qin, Shu-Kui, Cheng, Lu, Lu, Zu-Hong

“…Background Platinum-based chemotherapeutics are the most common regimens for advanced non-small-cell lung cancer （NSCLC） patients, and genetic factors are…”
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Safety and efficacy of first-line bevacizumab combined with taxane therapy in Chinese patients with HER2-negative locally recurrent or metastatic breast cancer： findings from the ATHENA study by Xu, Bing-he, Jiang, Ze-fei, Shen, Zhen-zhou, Guan, Zhong-zhen, Chen, Zheng-dong, Cheng, Ying, Zheng, Hong, Jiang, Jun, Wang, Xiao-jia, Tong, Zhong-sheng, Qin, Shu-kui, Luo, Yi, Yao, Min, Wang, Li-wei, He, Jing

“…Background Three randomised trials have demonstrated that combining bevacizumab with first-line chemotherapy significantly improves progression-free survival…”
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Silencing of high mobility group A1 enhances gemcitabine chemosensitivity of lung adenocarcinoma cells by Cao, Yuan-Dong, Huang, Pei-Lin, Sun, Xin-Chen, Ma, Jun, Jin, Zhi-Liang, Cheng, Hong-Yan, Xu, Rui-Zhi, Li, Fan, Qin, Shu-Kui, Deng, Yu-Xia, Ge, Xiao-Lin

“…Background The high mobility group A1 （HMGA1） proteins are architectural transcription factors found to be overexpressed in iung adenocarcinoma…”
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Identification of sphingosine kinase 1 (SphK1) as a primary target of icaritin in hepatocellular carcinoma cells by Lu, Pei-Hua, Chen, Min-Bin, Liu, Yuan-Yuan, Wu, Mian-Hua, Li, Wen-Ting, Wei, Mu-Xin, Liu, Chao-Ying, Qin, Shu-Kui

“…Hepatocellular carcinoma (HCC) is a highly aggressive neoplasm. We aim to explore the anti-HCC activity by a natural prenylflavonoid icaritin. Icaritin was…”
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Clinical practice guidelines for the treatment of primary liver cancer with integrative traditional Chinese and Western medicine by Ling, Chang-quan, Fan, Jia, Lin, Hong-sheng, Shen, Feng, Xu, Zhen-ye, Lin, Li-zhu, Qin, Shu-kui, Zhou, Wei-ping, Zhai, Xiao-feng, Li, Bai, Zhou, Qing-hui

“…Traditional Chinese medicine (TCM) is an important part of the treatment of primary liver cancer (PLC) in China; however, the current instructions for the…”
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