Search Results - "Qin, Pengxia"

RNA nanotherapeutics with fibrosis overexpression and retention for MASH treatment by Shan, Xinzhu, Zhao, Zhiqiang, Lai, Pingping, Liu, Yuxiu, Li, Buyao, Ke, Yubin, Jiang, Hanqiu, Zhou, Yilong, Li, Wenzhe, Wang, Qian, Qin, Pengxia, Xue, Yizhe, Zhang, Zihan, Wei, Chenlong, Ma, Bin, Liu, Wei, Luo, Cong, Lu, Xueguang, Lin, Jiaqi, Shu, Li, Jie, Yin, Xian, Xunde, Delcassian, Derfogail, Ge, Yifan, Miao, Lei

“…Metabolic dysfunction-associated steatohepatitis (MASH) poses challenges for targeted delivery and retention of therapeutic proteins due to excess…”
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Design, synthesis, and biological evaluation of novel N-Benzyl piperidine derivatives as potent HDAC/AChE inhibitors for Alzheimer’s disease by Qin, Pengxia, Ran, Yingying, Xie, Fei, Liu, Yujing, Wei, Chao, Luan, Xiaoyi, Wu, Jingde

“…[Display omitted] •Thirty-one compounds were designed and synthesized as HDAC/AChE inhibitors for AD.•d5 and d10 exhibited balanced dual enzyme inhibitions…”
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Recent development of selective inhibitors targeting the HDAC6 as anti-cancer drugs: Structure, function and design by Peng, Jie, Xie, Fei, Qin, Pengxia, Liu, Yujing, Niu, Haoqian, Sun, Jie, Xue, Haoyu, Zhao, Qianlong, Liu, Jingqian, Wu, Jingde

“…[Display omitted] •HDAC6 has emerged as a potential target for cancer treatment.•The use of benzene as linker is essential to improve HDAC6…”
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Recent advances of small molecule JNK3 inhibitors for Alzheimer’s disease by Qin, Pengxia, Ran, Yingying, Liu, Yujing, Wei, Chao, Luan, Xiaoyi, Niu, Haoqian, Peng, Jie, Sun, Jie, Wu, Jingde

“…[Display omitted] •JNK3 has become a promising drug target for Alzheimer’s disease.•Recent progress has been made in treating Alzheimer’s disease with JNK3…”
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