Search Results - "Qin, Mengtao"

234 Metabolic enhancement of alternately co-stimulated CART cells through AMPK creates functionally distinct phenotypes by Braverman, Erica, Qin, Mengtao, Schuler, Herbert, Byersdorfer, Craig

“…BackgroundChimeric antigen receptor (CAR) T cells have significantly improved our ability to treat cancer. However, these therapies suffer from metabolic and…”
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Graphene Oxide Hybridised TiO2 for Visible Light Photocatalytic Degradation of Phenol by Wang, Guanyu, Guo, Weijie, Xu, Deping, Liu, Di, Qin, Mengtao

“…In industrial pollutants, phenol is a kind of degradation-resistant hazardous compound. It is generated during industrial processes in factories and treatment…”
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CD19-CAR T Cytotoxicity Is Improved By AMPKγ2 Overexpression, Which Is Further Enhanced By Metformin Treatment by Qin, Mengtao, Braverman, Erica, Schuler, Herbert, Ramsey, Manda, Wittmann, Christopher, Byersdorfer, Craig

“…Background Acute lymphoblastic leukemia (ALL) is the most common leukemia found in children. Chimeric Antigen Receptor (CAR) T cells induce high response rates…”
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Abstract 45: Driving AMPK signaling in CD4+ CART cells enhances metabolic capacity, memory formation, and anti-leukemia activity by Braverman, Erica, Schuler, Herbert, Qin, Mengtao, Byersdorfer, Craig

“…Abstract Background: While Chimeric Antigen Receptor (CAR)T cell therapy has seen great success in pediatric and young adult acute lymphoblastic leukemia, up…”
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Overexpression of AMPKγ2 increases AMPK signaling to augment human T cell metabolism and function by Braverman, Erica L, McQuaid, Margaret A, Schuler, Herbert, Qin, Mengtao, Hani, Sophia, Hippen, Keli, Monlish, Darlene A, Dobbs, Andrea K, Ramsey, Manda J, Kemp, Felicia, Wittmann, Christopher, Ramgopal, Archana, Brown, Harrison, Blazar, Bruce, Byersdorfer, Craig A

“…Cellular therapies are currently employed to treat a variety of disease processes. For T cell-based therapies, success often relies on the metabolic fitness of…”
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AMPK drives both glycolytic and oxidative metabolism in murine and human T cells during graft-versus-host disease by Ramgopal, Archana, Braverman, Erica L., Sun, Lee-Kai, Monlish, Darlene, Wittmann, Christopher, Kemp, Felicia, Qin, Mengtao, Ramsey, Manda J., Cattley, Richard, Hawse, William, Byersdorfer, Craig A.

“…•AMPK plays a key role in driving both and oxidative and glycolytic metabolism in T cells during GVHD.•Absence of AMPK simultaneously impairs both glycolytic…”
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