Search Results - "Qin, Chu"

SVM-Prot 2016: A Web-Server for Machine Learning Prediction of Protein Functional Families from Sequence Irrespective of Similarity by Li, Ying Hong, Xu, Jing Yu, Tao, Lin, Li, Xiao Feng, Li, Shuang, Zeng, Xian, Chen, Shang Ying, Zhang, Peng, Qin, Chu, Zhang, Cheng, Chen, Zhe, Zhu, Feng, Chen, Yu Zong

“…Knowledge of protein function is important for biological, medical and therapeutic studies, but many proteins are still unknown in function. There is a need…”
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Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics by Li, Ying Hong, Yu, Chun Yan, Li, Xiao Xu, Zhang, Peng, Tang, Jing, Yang, Qingxia, Fu, Tingting, Zhang, Xiaoyu, Cui, Xuejiao, Tu, Gao, Zhang, Yang, Li, Shuang, Yang, Fengyuan, Sun, Qiu, Qin, Chu, Zeng, Xian, Chen, Zhe, Chen, Yu Zong, Zhu, Feng

“…Abstract Extensive efforts have been directed at the discovery, investigation and clinical monitoring of targeted therapeutics. These efforts may be…”
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NPASS: natural product activity and species source database for natural product research, discovery and tool development by Zeng, Xian, Zhang, Peng, He, Weidong, Qin, Chu, Chen, Shangying, Tao, Lin, Wang, Yali, Tan, Ying, Gao, Dan, Wang, Bohua, Chen, Zhe, Chen, Weiping, Jiang, Yu Yang, Chen, Yu Zong

“…Abstract There has been renewed interests in the exploration of natural products (NPs) for drug discovery, and continuous investigations of the therapeutic…”
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Microstructured Polyelectrolyte Elastomer‐Based Ionotronic Sensors with High Sensitivities and Excellent Stability for Artificial Skins by Yuan, Yi‐ming, Liu, Binhong, Adibeig, Mohammad Reza, Xue, Qiqi, Qin, Chu, Sun, Qing‐yin, Jin, Ying, Wang, Min, Yang, Canhui

“…High‐performance flexible pressure sensors are highly demanded for artificial tactile sensing. Using ionic conductors as the dielectric layer has enabled…”
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Boron-Doped g‑C6N6 Layer as a Metal-Free Photoelectrocatalyst for N2 Reduction Reaction by Chu, Zhao-Qin, Stampfl, Catherine, Duan, Xiang-Mei

“…Ammonia is one of the most important industrial chemicals due to its wide application in various fields. However, its synthesis requires heavy energy…”
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Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information by Yang, Hong, Qin, Chu, Li, Ying Hong, Tao, Lin, Zhou, Jin, Yu, Chun Yan, Xu, Feng, Chen, Zhe, Zhu, Feng, Chen, Yu Zong

“…Extensive drug discovery efforts have yielded many approved and candidate drugs targeting various targets in different biological pathways. Several freely…”
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LncRNA-MEG3 functions as a competing endogenous RNA to regulate Treg/Th17 balance in patients with asthma by targeting microRNA-17/ RORγt by Qiu, Yu-ying, Wu, Yan, Lin, Min-jie, Bian, Tao, Xiao, Yong-long, Qin, Chu

“…Treg/Th17 imbalance plays an essential role in the pathogenesis of asthma. Disordered LncRNAs were observed in asthma, however, whether LncRNAs can regulate…”
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Ar/NH3 Radio‐Frequency Plasma Etching and N‐doping to Stabilize Metallic Phase 1T‐MoS2 for Fast and Durable Sodium‐Ion Storage by Tian, Shijun, Chen, Weiheng, Wang, Ruoxing, Qin, Chu, Jiang, Zhong‐Jie, Jiang, Zhongqing

“…Metallic phase 1T‐MoS2 is considered a prospective anode material for sodium‐ion batteries (SIBs) due to its remarkable electrical conductivity and unique…”
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CMAUP: a database of collective molecular activities of useful plants by Zeng, Xian, Zhang, Peng, Wang, Yali, Qin, Chu, Chen, Shangying, He, Weidong, Tao, Lin, Tan, Ying, Gao, Dan, Wang, Bohua, Chen, Zhe, Chen, Weiping, Jiang, Yu Yang, Chen, Yu Zong

“…Abstract The beneficial effects of functionally useful plants (e.g. medicinal and food plants) arise from the multi-target activities of multiple ingredients…”
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Comprehensive Evaluation of End-Point Free Energy Techniques in Carboxylated-Pillar[6]arene Host-Guest Binding: III. Force-Field Comparison, Three-Trajectory Realization and Further Dielectric Augmentation by Liu, Xiao, Zheng, Lei, Qin, Chu, Cong, Yalong, Zhang, John Z H, Sun, Zhaoxi

“…Host-guest binding, despite the relatively simple structural and chemical features of individual components, still poses a challenge in computational…”
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Downregulation of PTEN mediates bleomycin-induced premature senescence in lung cancer cells by suppressing autophagy by Sai, Xiaoyan, Qin, Chu, Wu, Yan, Zhao, Yinying, Bian, Tao

“…Objective Bleomycin is an important chemotherapeutic drug that activates premature senescence to decrease the tumorigenic process. We aimed to investigate the…”
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The effect of protease inhibitors‐based antiretroviral therapy on serum/plasma interleukin‐6 levels among PLHIV: a systematic review and meta‐analysis by Ashuro, Akililu Alemu, Zhang, Si‐Chen, Wang, Ting, Chu, Qin‐Shu, Fu, Yuan‐Sheng, Fan, Yin‐Guang, Ye, Dong‐Qing

“…Recommended treatment regimen for human immune deficiency virus (HIV) infection includes protease inhibitors/ritonavir (PIs/r) combined with two‐nucleoside…”
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Let‐7 mediated airway remodelling in chronic obstructive pulmonary disease via the regulation of IL‐6 by Di, Tingting, Yang, Yue, Fu, Congli, Zhang, Zixiao, Qin, Chu, Sai, Xiaoyan, Liu, Jiaxin, Hu, Caixia, Zheng, Mingfeng, Wu, Yan, Bian, Tao

“…Background Myofibroblast differentiation and extracellular matrix (ECM) deposition are observed in chronic obstructive pulmonary disease (COPD). However, the…”
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Rational Design of Hollow Structural Materials for Sodium‐Ion Battery Anodes by Qin, Chu, Jiang, Zhong‐Jie, Maiyalagan, Thandavarayan, Jiang, Zhongqing

“…The development of sodium‐ion battery (SIB) anodes is still hindered by their rapid capacity decay and poor rate capabilities. Although there have been some…”
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Towards Understanding Attention-Based Speech Recognition Models by Qin, Chu-Xiong, Qu, Dan

“…Although the attention-based speech recognition has achieved promising performances, the specific explanation of the intermediate representations remains a…”
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Out-of-the-box deep learning prediction of pharmaceutical properties by broadly learned knowledge-based molecular representations by Shen, Wan Xiang, Zeng, Xian, Zhu, Feng, Wang, Ya li, Qin, Chu, Tan, Ying, Jiang, Yu Yang, Chen, Yu Zong

“…Successful deep learning critically depends on the representation of the learned objects. Recent state-of-the-art pharmaceutical deep learning models…”
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SENP6 induces microglial polarization and neuroinflammation through de-SUMOylation of Annexin-A1 after cerebral ischaemia–reperfusion injury by Mao, Meng, Xia, Qian, Zhan, Gao-Feng, Chu, Qin-Jun, Li, Xing, Lian, Hong-Kai

“…Abstract Background Previous data have reported that Sentrin/SUMO-specific protease 6 (SENP6) is involved in ischaemic brain injury and induces neuronal…”
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Clustered patterns of species origins of nature-derived drugs and clues for future bioprospecting by Zhu, Feng, Qin, Chu, Tao, Lin, Liu, Xin, Shi, Zhe, Ma, Xiaohua, Jia, Jia, Tan, Ying, Cui, Cheng, Lin, Jinshun, Tan, Chunyan, Jiang, Yuyang, Chen, Yuzong

“…Many drugs are nature derived. Low drug productivity has renewed interest in natural products as drug-discovery sources. Nature-derived drugs are composed of…”
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Therapeutic target database update 2014: a resource for targeted therapeutics by Qin, Chu, Zhang, Cheng, Zhu, Feng, Xu, Feng, Chen, Shang Ying, Zhang, Peng, Li, Ying Hong, Yang, Sheng Yong, Wei, Yu Quan, Tao, Lin, Chen, Yu Zong

“…Here we describe an update of the Therapeutic Target Database (http://bidd.nus.edu.sg/group/ttd/ttd.asp) for better serving the bench-to-clinic communities and…”
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Towards end-to-end speech recognition with transfer learning by Qin, Chu-Xiong, Qu, Dan, Zhang, Lian-Hai

“…A transfer learning-based end-to-end speech recognition approach is presented in two levels in our framework. Firstly, a feature extraction approach combining…”
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